Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Murali Dharan Bashyam"'
Autor:
Raju S R Adduri, Rajender Katamoni, Ramaswamy Pandilla, Sandeep N Madana, Arun Kumar Paripati, Viswakalyan Kotapalli, Murali Dharan Bashyam
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114002 (2014)
PURPOSE:The tumor suppressor p53 is known to be inactivated frequently in various cancers. In addition, germline polymorphisms in TP53 are known to affect protein function and influence risk of developing different types of cancers. In this study, we
Externí odkaz:
https://doaj.org/article/e4fb1a4412fe45d39862df488780aeff
Despite seminal advances towards understanding the infection mechanism of SARS-CoV-2, it continues to cause significant morbidity and mortality worldwide. Though mass immunization programs have been implemented in several countries, the viral transmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524ba1df5b1dc95255bfaabad05e7f13
https://doi.org/10.1099/acmi.0.000513.v1
https://doi.org/10.1099/acmi.0.000513.v1
Colorectal cancer (CRC) appears to arise from sequential genetic lesions in tumor suppressor genes (APC, SMAD4 and TP53) and oncogenes (KRAS) leading to the classical adenoma to carcinoma progression. Biallelic APC inactivating genetic aberrations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbeb11002f23e2cd56b541c970b3c6f
https://doi.org/10.1101/2022.05.24.493182
https://doi.org/10.1101/2022.05.24.493182
Despite seminal advances towards understanding its infection mechanism, SARS-CoV-2 continues to cause significant morbidity and mortality worldwide. Though mass immunization programs have been implemented in several countries, the viral transmission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3758b1244d89000603c8c225d19774a9
https://doi.org/10.1101/2022.01.19.22269572
https://doi.org/10.1101/2022.01.19.22269572
Autor:
Sanket Desai, Bhasker Dharavath, Sujith Manavalan, Aishwarya Rane, Archana Kumari Redhu, Roma Sunder, Ashwin Butle, Rohit Mishra, Asim Joshi, Trupti Togar, Shruti Apte, Pratyusha Bala, Pratik Chandrani, Supriya Chopra, Murali Dharan Bashyam, Anirban Banerjee, Kumar Prabhash, Sudhir Nair, Amit Dutt
Publikováno v:
NAR Cancer. 4
Persistent pathogen infection is a known cause of malignancy, although with sparse systematic evaluation across tumor types. We present a comprehensive landscape of 1060 infectious pathogens across 239 whole exomes and 1168 transcriptomes of breast,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2229900c900d25a319035a589b2881a5
https://doi.org/10.1093/narcan/zcac006
https://doi.org/10.1093/narcan/zcac006
Publikováno v:
Cancer Research. 82:751-751
Implementation of regular screening and adoption of a healthier lifestyle has resulted in a steady decline of colorectal cancer (CRC) incidence in the USA over the past few decades. On the contrary, early-onset sporadic rectal cancer (EOSRC) has exhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bee46c9d49fc40e32f2b78459cd18d6
https://doi.org/10.1158/1538-7445.am2022-751
https://doi.org/10.1158/1538-7445.am2022-751
Autor:
Pratyusha, Bala, Anurag Kumar, Singh, Padmavathi, Kavadipula, Viswakalyan, Kotapalli, Radhakrishnan, Sabarinathan, Murali Dharan, Bashyam
Publikováno v:
Oncogene. 40(4)
Early-onset sporadic rectal cancer (EOSRC) is a unique and predominant colorectal cancer (CRC) subtype in India. In order to understand the tumorigenic process in EOSRC, we performed whole-exome sequencing of 47 microsatellite stable EOSRC samples. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ef9998093f21485805825358a83708c
https://pubmed.ncbi.nlm.nih.gov/33262464
https://pubmed.ncbi.nlm.nih.gov/33262464
Publikováno v:
Cancer Research. 79:3490-3490
Background: CRC is the 3rd most commonly diagnosed malignancy and 4th leading cause of cancer related deaths worldwide. Over two decades of extensive research from the West has revealed three major tumorigenesis pathways responsible for CRC viz. a) C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05f95b72150323e18c8709eca15ff45
https://doi.org/10.1158/1538-7445.am2019-3490
https://doi.org/10.1158/1538-7445.am2019-3490