Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Muraleedharan K. Manheri"'
Autor:
Jais Kurian, Muraleedharan K. Manheri, Ashan Manhas, Ramshad Kalluruttimmal, Mohammad Anas, Saheer V. Chaluvalappil, Varsha Kumari, Niti Kumar
Publikováno v:
ChemMedChem. 17(2)
Although many quinolones have shown promise as potent antimalarials, their clinical development has been slow due to poor performance in vivo. Insights into structural modifications that can improve their therapeutic potential will be very valuable i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5407775fe5c42ba38c8a1e624a5398
https://pubmed.ncbi.nlm.nih.gov/34717044
https://pubmed.ncbi.nlm.nih.gov/34717044
Autor:
Archana Panthalattu Parambil, Muraleedharan K. Manheri, Lakshmi Chakkumkumarath, Divya Thekke Thattariyil, Ramshad Kalluruttimmal, Ashis Kumar Sen
Publikováno v:
The Analyst. 144:4210-4218
A sensor for the detection and quantification of H2S in biological samples should ideally meet a set of criteria such as fast detection, high sensitivity in the desired concentration range, high selectivity, non-interference from biomolecules like pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0adee75eed5101658a0cfbf5d20ffcbe
https://doi.org/10.1039/c9an00522f
https://doi.org/10.1039/c9an00522f
Autor:
Karunagaran Devarajan, Nalini Venkatesan, Soumya Saroj, Muraleedharan K. Manheri, Sateeshkumar Kumbhakonam
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(22)
New cisplatin analogs in which the diamminedichloro-Pt(II) unit is conjugated to dihydroquinoline- or tetrahydroquinoline frameworks were synthesized and subjected to biological evaluation in order to understand their effects on cellular redox homeos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e5b24516c3ad68ee93b7af824080f2
https://pubmed.ncbi.nlm.nih.gov/33010449
https://pubmed.ncbi.nlm.nih.gov/33010449
Autor:
Muraleedharan K. Manheri, Devarajan Karunagaran, Nalini Venkatesan, Sateeshkumar Kumbhakonam, Soumya Saroj, Kasipandi Vellaisamy
Publikováno v:
New Journal of Chemistry. 42:2450-2458
A modular strategy that allows introduction of one or more reactive platinum units at chosen locations along a peptide sequence is presented. This makes use of diazides generated from serine and threonine as diamine equivalents which can be conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e83e8d3f1892f43cfb218aadbf41c4e0
https://doi.org/10.1039/c7nj03999a
https://doi.org/10.1039/c7nj03999a
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 112
A new group of non-ionic amphiphiles with short alkyl chains and functionalizable oxanorbornane-based head group for drug delivery application are presented. They can be prepared through a sequence that starts with cycloaddition of Boc-protected furf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdd2c9ec860840adb876b43f6ffc6c8
https://pubmed.ncbi.nlm.nih.gov/32409031
https://pubmed.ncbi.nlm.nih.gov/32409031
Publikováno v:
RSC Advances. 6:29197-29201
Fine-tuning the gelation ability of aryl triazolyl peptide 1 by C-terminal modification led to the identification of 2 with the remarkable ability to form highly transparent gels in a wide range of solvents including oils. Good rheological properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb136c500e74b353886ab8ac2a305cb
https://doi.org/10.1039/c6ra01282e
https://doi.org/10.1039/c6ra01282e
Publikováno v:
Chirality. 31(4)
Lipase-catalysed enantioselective acetylation and deacetylation routes were investigated to prepare 1,5,6-trisubstituted 7-oxabicyclo[2.2.1]hept-2-ene skeleton in enantio-pure form. The racemic alcohol (6) used in acetylation reaction was accessed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7dd444d8529312d2ac468653f9954e9
https://pubmed.ncbi.nlm.nih.gov/30753757
https://pubmed.ncbi.nlm.nih.gov/30753757
Publikováno v:
Chemical communications (Cambridge, England). 53(32)
A simple replacement of a H atom by Br transformed non-gelating aryl triazolyl amino acid benzyl ester into a versatile gelator, which formed shape-persistent, self-healing and mouldable gels. The ‘bromo-aryl benzyl ester’ fragment was then trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb500dbb2a67a1f7cb1023e4144c5bd
https://pubmed.ncbi.nlm.nih.gov/28382364
https://pubmed.ncbi.nlm.nih.gov/28382364
Autor:
Sridevi Duggirala, V. Senu Adeeba, Muraleedharan K. Manheri, Mukesh Doble, John Victor Napoleon, Rakesh P. Nankar
Publikováno v:
European journal of medicinal chemistry. 123
The dual effect of FtsZ inhibition and oxidative stress by a group of 1,2-dihydroquinolines that culminate in bactericidal effect on mycobacterium strains is demonstrated. They inhibited the non-pathogenic Mycobacterium smegmatis mc2 155 with MIC as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa17be8683db2c604295892372b68d1
https://pubmed.ncbi.nlm.nih.gov/27517804
https://pubmed.ncbi.nlm.nih.gov/27517804
Publikováno v:
Synthesis. 2011:3379-3388
When subjected to tandem SN2-SNAr cyclization in the presence of alkyl or aralkyl amines, Baylis-Hillman acetates gave the corresponding 1,2-dihydroquinolines, which on simple exposure to light and oxygen afforded the corresponding 4- and 2-quinolone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18a7bdbac1c92bceb04b6dc9630fbe4
https://doi.org/10.1055/s-0030-1260189
https://doi.org/10.1055/s-0030-1260189