Antitubercular Bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and in Vivo Studies.

Autor: Spain M; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Wong JK; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Nagalingam G; Microbial Immunity and Pathogenesis Group, Department of Infectious Diseases and Immunology, Sydney Medical School , The University of Sydney , Sydney , NSW 2006 , Australia., Batten JM; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Hortle E; Tuberculosis Research Program , Centenary Institute, Royal Prince Alfred Hospital , Missenden Road , Camperdown, Sydney , NSW 2050 , Australia., Oehlers SH; Central Clinical School, Sydney Medical School , The University of Sydney , Sydney , NSW 2006 , Australia., Jiang XF; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Murage HE; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Orford JT; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Crisologo P; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Triccas JA; Microbial Immunity and Pathogenesis Group, Department of Infectious Diseases and Immunology, Sydney Medical School , The University of Sydney , Sydney , NSW 2006 , Australia., Rutledge PJ; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia., Todd MH; School of Chemistry , The University of Sydney , Sydney , NSW 2006 , Australia.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Apr 26; Vol. 61 (8), pp. 3595-3608. Date of Electronic Publication: 2018 Apr 05.