Microglial contribution to the pathology of neurodevelopmental disorders in humans.

Autor: Matuleviciute R; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Akinluyi ET; Division of Medical Sciences, University of Victoria, Victoria, Canada.; Department of Pharmacology and Therapeutics, Afe Babalola University, Ado Ekiti, Nigeria., Muntslag TAO; Princess Maxima Centre for Paediatric Oncology, Utrecht, The Netherlands., Dewing JM; Faculty of Medicine, University of Southampton, Southampton, UK., Long KR; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.; Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Vernon AC; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK.; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Tremblay ME; Division of Medical Sciences, University of Victoria, Victoria, Canada., Menassa DA; Department of Neuropathology & The Queen's College, University of Oxford, Oxford, UK. david.menassa@clneuro.ox.ac.uk.; Department of Women's and Children's Health, Karolinska Institutet, Solna, Sweden. david.menassa@clneuro.ox.ac.uk.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2023 Nov; Vol. 146 (5), pp. 663-683. Date of Electronic Publication: 2023 Sep 01.

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology.

Autor: Hu Y; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Fryatt GL; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Ghorbani M; Antibody and Vaccine Group, Centre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK., Obst J; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Menassa DA; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Martin-Estebane M; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Muntslag TAO; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Olmos-Alonso A; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Guerrero-Carrasco M; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Thomas D; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK., Cragg MS; Antibody and Vaccine Group, Centre for Cancer Immunology, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK., Gomez-Nicola D; School of Biological Sciences, University of Southampton, Southampton General Hospital, Southampton, UK. Electronic address: d.gomez-nicola@soton.ac.uk.

Publikováno v: Cell reports [Cell Rep] 2021 Jun 08; Vol. 35 (10), pp. 109228.