Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model.

Autor: Megane Penalva YC; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H3G 0B1.; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada H3A 2B4.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montréal H3G 0B1, Québec, Canada., Paschkowsky S; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H3G 0B1.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1., Yang J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA., Recinto SJ; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H3G 0B1.; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada H3A 2B4.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1., Cinkorpumin J; Department of Biochemistry, McGill University, Montreal, QC, Canada H3G 0B1., Hernandez MR; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H3G 0B1.; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada H3A 2B4.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montréal H3G 0B1, Québec, Canada., Xiao B; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada H3A 2B4.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montréal H3G 0B1, Québec, Canada., Nitu A; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada H3A 2B4.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montréal H3G 0B1, Québec, Canada., Yee-Li Wu H; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H3G 0B1.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1., Munter HM; Department of Human Genetics, McGill University, Montreal, QC, Canada H3A 0C7., Michalski B; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada., Fahnestock M; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada., Pastor W; Department of Biochemistry, McGill University, Montreal, QC, Canada H3G 0B1., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA., Munter LM; Department of Pharmacology & Therapeutics, McGill University, Montreal, QC, Canada H3G 0B1.; Cell Information Systems group, Bellini Life Sciences Complex, McGill University, Montreal, QC, Canada H3G 0B1.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montréal H3G 0B1, Québec, Canada.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 08. Date of Electronic Publication: 2024 Sep 08.

Circulating plasma fibronectin affects tissue insulin sensitivity, adipocyte differentiation, and transcriptional landscape of adipose tissue in mice.

Autor: Mahmoodi M; Faculty of Dental Medicine and Oral Health Sciences (Biomedical Sciences), McGill University, Montreal, Quebec, Canada., Mirzarazi Dahagi E; Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada., Nabavi MH; Faculty of Dental Medicine and Oral Health Sciences (Biomedical Sciences), McGill University, Montreal, Quebec, Canada., Penalva YCM; Department of Pharmacology & Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montreal, Quebec, Canada., Gosaine A; Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada., Murshed M; Faculty of Dental Medicine and Oral Health Sciences (Biomedical Sciences), McGill University, Montreal, Quebec, Canada.; Shriners Hospital for Children, Montreal, Quebec, Canada., Couldwell S; Faculty of Dental Medicine and Oral Health Sciences (Biomedical Sciences), McGill University, Montreal, Quebec, Canada., Munter LM; Department of Pharmacology & Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada.; Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montreal, Quebec, Canada., Kaartinen MT; Faculty of Dental Medicine and Oral Health Sciences (Biomedical Sciences), McGill University, Montreal, Quebec, Canada.; Department of Anatomy and Cell Biology, Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada.; Department of Medicine (Division of Experimental Medicine), Faculty of Medicine and Health Sciences, McGill University, Montreal, Quebec, Canada.

Publikováno v: Physiological reports [Physiol Rep] 2024 Jul; Vol. 12 (14), pp. e16152.

Putative Protein Interactome of the Rhomboid Protease RHBDL4.

Autor: Hsiao JM; Department of Biochemistry, McGill University, Montreal H3G 0B1, Québec, Canada., Penalva YCM; Department of Pharmacology & Therapeutics, McGill University, Montreal H3G 0B1, Québec, Canada.; Integrated Program in Neuroscience, McGill University, Montreal H3A 2B4, Québec, Canada.; Cell Information Systems Group, Bellini Life Sciences Complex, McGill University, Montreal H3G 0B1, Québec, Canada., Wu HY; Department of Pharmacology & Therapeutics, McGill University, Montreal H3G 0B1, Québec, Canada.; Cell Information Systems Group, Bellini Life Sciences Complex, McGill University, Montreal H3G 0B1, Québec, Canada., Xiao B; Department of Pharmacology & Therapeutics, McGill University, Montreal H3G 0B1, Québec, Canada.; Cell Information Systems Group, Bellini Life Sciences Complex, McGill University, Montreal H3G 0B1, Québec, Canada., Jansen G; Department of Biochemistry, McGill University, Montreal H3G 0B1, Québec, Canada., Dejgaard K; Department of Biochemistry, McGill University, Montreal H3G 0B1, Québec, Canada., Young JC; Department of Biochemistry, McGill University, Montreal H3G 0B1, Québec, Canada., Munter LM; Department of Pharmacology & Therapeutics, McGill University, Montreal H3G 0B1, Québec, Canada.; Cell Information Systems Group, Bellini Life Sciences Complex, McGill University, Montreal H3G 0B1, Québec, Canada.

Publikováno v: Biochemistry [Biochemistry] 2023 Mar 21; Vol. 62 (6), pp. 1209-1218. Date of Electronic Publication: 2023 Mar 01.

The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain.

Autor: Oestereich F; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada; Cell Information Systems Group, Bellini Life Sciences Complex, Montreal, Québec, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Québec, Canada., Yousefpour N; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada., Yang E; Department of Chemistry, Université de Montréal, Montreal, Québec, Canada., Phénix J; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada; Cell Information Systems Group, Bellini Life Sciences Complex, Montreal, Québec, Canada., Nezhad ZS; Department of Chemistry, Université de Montréal, Montreal, Québec, Canada., Nitu A; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada; Cell Information Systems Group, Bellini Life Sciences Complex, Montreal, Québec, Canada., Vázquez Cobá A; Cell Information Systems Group, Bellini Life Sciences Complex, Montreal, Québec, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Québec, Canada., Ribeiro-da-Silva A; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada., Chaurand P; Department of Chemistry, Université de Montréal, Montreal, Québec, Canada., Munter LM; Department of Pharmacology and Therapeutics, McGill University, Montreal, Québec, Canada; Cell Information Systems Group, Bellini Life Sciences Complex, Montreal, Québec, Canada. Electronic address: lisa.munter@mcgill.ca.

Publikováno v: Journal of lipid research [J Lipid Res] 2022 Sep; Vol. 63 (9), pp. 100260. Date of Electronic Publication: 2022 Jul 31.