Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents.

Autor: Thiabaud G; Department of Chemistry, University of Texas at Austin, Austin, TX 78712-1224., He G; Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX 77030., Sen S; Department of Chemistry, University of Texas at Austin, Austin, TX 78712-1224., Shelton KA; Department of Comparative Medicine, MD Anderson Cancer Center, Bastrop, TX 78602., Baze WB; Department of Comparative Medicine, MD Anderson Cancer Center, Bastrop, TX 78602., Segura L; Department of Comparative Medicine, MD Anderson Cancer Center, Bastrop, TX 78602., Alaniz J; Department of Chemistry, University of Texas at Austin, Austin, TX 78712-1224., Munoz Macias R; Department of Chemistry, University of Texas at Austin, Austin, TX 78712-1224., Lyness G; Drug Dynamics Institute, College of Pharmacy, University of Texas at Austin, Austin, TX 78712-1224., Watts AB; Drug Dynamics Institute, College of Pharmacy, University of Texas at Austin, Austin, TX 78712-1224., Kim HM; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Korea., Lee H; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Korea., Cho MY; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Korea., Hong KS; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Korea., Finch R; Department of Comparative Medicine, MD Anderson Cancer Center, Bastrop, TX 78602; rafinch@mdanderson.org zsiddik@mdanderson.org jfarambula@cm.utexas.edu sessler@cm.utexas.edu., Siddik ZH; Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX 77030; rafinch@mdanderson.org zsiddik@mdanderson.org jfarambula@cm.utexas.edu sessler@cm.utexas.edu., Arambula JF; Department of Chemistry, University of Texas at Austin, Austin, TX 78712-1224; rafinch@mdanderson.org zsiddik@mdanderson.org jfarambula@cm.utexas.edu sessler@cm.utexas.edu.; OncoTEX Inc., Austin, TX 78701., Sessler JL; Department of Chemistry, University of Texas at Austin, Austin, TX 78712-1224; rafinch@mdanderson.org zsiddik@mdanderson.org jfarambula@cm.utexas.edu sessler@cm.utexas.edu.; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Korea.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Mar 31; Vol. 117 (13), pp. 7021-7029. Date of Electronic Publication: 2020 Mar 16.