Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Munir R. Tanas"'
Autor:
Amira Zaher, Kranti A. Mapuskar, Michael S. Petronek, Munir R. Tanas, Alexandra L. Isaacson, Rebecca D. Dodd, Mohammed Milhem, Muhammad Furqan, Douglas R. Spitz, Benjamin J. Miller, Robert A. Beardsley, Bryan G. Allen
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 587 (2024)
Soft tissue sarcomas (STSs) are mesenchymal malignant lesions that develop in soft tissues. Despite current treatments, including radiation therapy (RT) and surgery, STSs can be associated with poor patient outcomes and metastatic recurrences. Neoadj
Externí odkaz:
https://doaj.org/article/b0197ae339824cb0bd61d1901b655ed0
Autor:
Melissa A. Marchal, Devon L. Moose, Afshin Varzavand, Nicole E. Jordan, Destiney Taylor, Munir R. Tanas, James A. Brown, Michael D. Henry, Christopher S. Stipp
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAbl family kinases function as proto-oncogenes in various leukemias, and pro-tumor functions have been discovered for Abl kinases in many solid tumors as well. However, a growing body of evidence indicates that Abl kinases can function to
Externí odkaz:
https://doaj.org/article/3f74f3b22e7d4202910ff27fb642931d
Autor:
Qierra R. Brockman, Amanda Scherer, Gavin R. McGivney, Wade R. Gutierrez, Andrew P. Voigt, Alexandra L. Isaacson, Emily A. Laverty, Grace Roughton, Vickie Knepper-Adrian, Benjamin Darbro, Munir R. Tanas, Christopher S. Stipp, Rebecca D. Dodd
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
The histone methyltransferase PRC2 plays a complex role in cancer. Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas with frequent loss-of-function mutations in PRC2 that are associated with poor outcome. Here, we identify a c
Externí odkaz:
https://doaj.org/article/72aae0cfd35e4271a50d462f47391a87
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 20, Iss , Pp 100955- (2020)
Purpose: Myofibromas are benign soft tissue tumors commonly encountered in infancy and childhood. Developing usually within the first two years of life, they can be multicentric and involve deep visceral organs. Observations: We present the rare occu
Externí odkaz:
https://doaj.org/article/f2782450891743d3a7d6a5492e768ba6
Autor:
Brian P. Rubin, Munir R. Tanas
Publikováno v:
Rare Tumors, Vol 1, Iss 2, Pp e26-e26 (2009)
Malignant melanoma can metastasize widely and vary significantly in its histological appearance; it rarely presents as a deep-seated mass without an obvious primary site elsewhere. Malignant peripheral nerve sheath tumor (MPNST) is a high-grade sarco
Externí odkaz:
https://doaj.org/article/3e55fa37af6c489f94ca6d2c702512cf
Autor:
Dawn E. Quelle, Munir R. Tanas, Benjamin W. Darbro, Rebecca D. Dodd, Jill M. Weimer, K.D. Zamba, David K. Meyerholz, Mariah R. Leidinger, Jessica C. Sieren, Rajesh Khanna, Vickie Knepper-Adrian, Kendall E. Cornick, Heather J. Major, Allison Moreno Samayoa, Chandra K. Maharjan, Casey Pulliam, Courtney A. Kaemmer, Jordan L. Kohlmeyer
RNA-Seq Gene Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920ee80e1af2be68a88f0ab59c9465b2
https://doi.org/10.1158/1078-0432.22475733
https://doi.org/10.1158/1078-0432.22475733
Autor:
Dawn E. Quelle, Munir R. Tanas, Benjamin W. Darbro, Rebecca D. Dodd, Jill M. Weimer, K.D. Zamba, David K. Meyerholz, Mariah R. Leidinger, Jessica C. Sieren, Rajesh Khanna, Vickie Knepper-Adrian, Kendall E. Cornick, Heather J. Major, Allison Moreno Samayoa, Chandra K. Maharjan, Casey Pulliam, Courtney A. Kaemmer, Jordan L. Kohlmeyer
Purpose:Malignant peripheral nerve sheath tumors (MPNST) are deadly sarcomas that lack effective therapies. In most MPNSTs, the retinoblastoma (RB1) tumor suppressor is disabled by hyperactivation of cyclin-dependent kinases (CDK), commonly through l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dd56d880240716d96cf8ae8c86d42c
https://doi.org/10.1158/1078-0432.c.6529155
https://doi.org/10.1158/1078-0432.c.6529155
Autor:
Dawn E. Quelle, Munir R. Tanas, Benjamin W. Darbro, Rebecca D. Dodd, Jill M. Weimer, K.D. Zamba, David K. Meyerholz, Mariah R. Leidinger, Jessica C. Sieren, Rajesh Khanna, Vickie Knepper-Adrian, Kendall E. Cornick, Heather J. Major, Allison Moreno Samayoa, Chandra K. Maharjan, Casey Pulliam, Courtney A. Kaemmer, Jordan L. Kohlmeyer
Antibody Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1847e45ac5123d2616c4dc83595c77c3
https://doi.org/10.1158/1078-0432.22475736.v1
https://doi.org/10.1158/1078-0432.22475736.v1
Autor:
Anna C. Reisetter, Sadanandan E. Velu, Jordan L. Kohlmeyer, Mariah R. Leidinger, Georgina K. Ofori-Amanfo, Dawn E. Quelle, Parmanand Ahirwar, Chandni Desai, Khadijeh Jahanseir, Jon Thomason, Patrick Breheny, Karen J. Fritchie, Munir R. Tanas
Publikováno v:
Oncotarget
Additional prognostic and therapeutic biomarkers effective across different histological types of sarcoma are needed. Herein we evaluate expression of TAZ and YAP, the p53-MDM2 axis, and RABL6A, a novel oncoprotein with potential ties to both pathway
Autor:
Varun Monga, Munir R. Tanas, Rebecca D. Dodd, David Gordon, Jordan L. Kohlmeyer, Benjamin W. Darbro, Dawn E. Quelle
Publikováno v:
Oncotarget
Precision medicine relies on a detailed molecular understanding of disease pathogenesis. Here, we consider urgently needed therapeutic options for malignant peripheral nerve sheath tumors (MPNSTs) based on emerging insights into druggable pathway alt