Zobrazeno 1 - 10
of 819
pro vyhledávání: '"Munir Pirmohamed"'
Autor:
Joshua Gardner, Simon Timothy Abrams, Cheng-Hock Toh, Alan L. Parker, Charlotte Lovatt, Phillip L. R. Nicolson, Steve P. Watson, Sophie Grice, Luisa Hering, Munir Pirmohamed, Dean J. Naisbitt
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Vaccination has proven to be a valuable tool to combat SARS-CoV-2. However, reports of rare adverse reactions such as thrombosis/thrombocytopenia syndrome after ChAdOx1 nCoV-19 vaccination have caused scientific, public and media concern. Ch
Externí odkaz:
https://doaj.org/article/be965df4a61b41da8cb7ac9187ad011c
Autor:
Dung T. Tran, Yulu Chen, Yi Zheng, Julian Hecker, Daniel B. Hawcutt, Munir Pirmohamed, Jessica Lasky‐Su, Ann C. Wu, Kelan G. Tantisira, Michael J. McGeachie, Scott T. Weiss, Amber Dahlin
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Background Asthma is routinely treated with inhaled corticosteroids (ICS). Asthma patients on ICS are at increased risk of adrenal suppression, a potentially serious effect of long‐term glucocorticoid exposure; however, this relationship i
Externí odkaz:
https://doaj.org/article/60b2a9ad4aa34a2195c7359ad42f4016
Autor:
Munir Pirmohamed, Ronald Kiguba, Helen Byomire Ndagije, Phil Tregunno, Kendal Harrison, Gerald Isabirye, Julius Mayengo, Jonathan Owiny
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objectives Pharmacovigilance databases play a critical role in monitoring drug safety. The duplication of reports in pharmacovigilance databases, however, undermines their data integrity. This scoping review sought to provide a comprehensive understa
Externí odkaz:
https://doaj.org/article/b73d8e7a506d4f7888e02c25468cccfb
Autor:
Sylvia Hartmann, Summaira Yasmeen, Benjamin M. Jacobs, Spiros Denaxas, Munir Pirmohamed, Eric R. Gamazon, Mark J. Caulfield, Genes & Health Research Team, Harry Hemingway, Maik Pietzner, Claudia Langenberg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Raynaud’s phenomenon (RP) is a common vasospastic disorder that causes severe pain and ulcers, but despite its high reported heritability, no causal genes have been robustly identified. We conducted a genome-wide association study includin
Externí odkaz:
https://doaj.org/article/afa46f3656294092abb905cb5110852c
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100896- (2023)
Background & Aims: Population screening for non-alcoholic fatty liver disease (NAFLD) and associated comorbidities remains an unaddressed clinical need. We aimed to assess the utility of the fatty liver index (FLI) for risk stratification of NAFLD an
Externí odkaz:
https://doaj.org/article/0858a8ffa8144ffa8d1c9923d9707b8c
Autor:
Madeline E. Marks, Ramya Krishna Botta, Riichiro Abe, Thomas M. Beachkofsky, Isabelle Boothman, Bruce C. Carleton, Wen-Hung Chung, Ricardo R. Cibotti, Roni P. Dodiuk-Gad, Christian Grimstein, Akito Hasegawa, Jay H. Hoofnagle, Shuen-Iu Hung, Benjamin Kaffenberger, Daniela Kroshinsky, Rannakoe J. Lehloenya, Michelle Martin-Pozo, Robert G. Micheletti, Maja Mockenhaupt, Keisuke Nagao, Suman Pakala, Amy Palubinsky, Helena B. Pasieka, Jonathan Peter, Munir Pirmohamed, Melissa Reyes, Hajirah N. Saeed, Jeffery Shupp, Chonlaphat Sukasem, Jhih Yu Syu, Mayumi Ueta, Li Zhou, Wan-Chun Chang, Patrice Becker, Teresa Bellon, Kemberlee Bonnet, Gianpiero Cavalleri, James Chodosh, Anna K. Dewan, Arturo Dominguez, Xinzhong Dong, Elena Ezhkova, Esther Fuchs, Jennifer Goldman, Sonia Himed, Simon Mallal, Alina Markova, Kerry McCawley, Allison E. Norton, David Ostrov, Michael Phan, Arthur Sanford, David Schlundt, Daniel Schneider, Neil Shear, Kanade Shinkai, Eric Tkaczyk, Jason A. Trubiano, Simona Volpi, Charles S. Bouchard, Sherrie J. Divito, Elizabeth J. Phillips
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) is a predominantly drug-induced disease, with a mortality rate of 15–20%, that engages the expertise of multiple disciplines: dermatology, allergy, immunology, clinical pharmacology, bur
Externí odkaz:
https://doaj.org/article/83a942713faf4a3ab1f40a9ad2a0e4a0
Autor:
Laurence McEvoy, Joanne Cliff, Daniel F Carr, Andrea Jorgensen, Rosemary Lord, Munir Pirmohamed
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a3c8e82000e0421da1091e42cd43e71c
Autor:
Andrea L Jorgensen, Catherine Orrell, Catriona Waitt, Cheng-Hock Toh, Christine Sekaggya-Wiltshire, Dyfrig A Hughes, Elizabeth Allen, Emmy Okello, Gayle Tatz, Giovanna Culeddu, Innocent G Asiimwe, Jerome Roy Semakula, Johannes P Mouton, Karen Cohen, Marc Blockman, Mohammed Lamorde, Munir Pirmohamed
Publikováno v:
JMIR Research Protocols, Vol 12, p e46710 (2023)
BackgroundThe quality of warfarin anticoagulation among Sub-Saharan African patients is suboptimal. This is due to several factors, including a lack of standardized dosing algorithms, difficulty in providing timely international normalized ratio (INR
Externí odkaz:
https://doaj.org/article/8aa9d5caf1144261bbc13fcb1b01ef6e
Autor:
Laurence McEvoy, Joanne Cliff, Daniel F Carr, Andrea Jorgensen, Rosemary Lord, Munir Pirmohamed
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Taxane-induced peripheral neuropathy (TIPN) is an important cause of premature treatment cessation and dose-limitation in cancer therapy. It also reduces quality of life and survivorship in affected patients. Genetic polymorphisms in the
Externí odkaz:
https://doaj.org/article/450ffb5622de4e6999b1cea3b924fac5
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Diagnostics require precision and predictive ability to be clinically useful. Integration of multi-omic with clinical data is crucial to our understanding of disease pathogenesis and diagnosis. However, interpretation of overwhelming amounts of infor
Externí odkaz:
https://doaj.org/article/45274395e84c47f5ad78ae3db2604bf1