Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Munir, Akkaya"'
Autor:
Munir Akkaya, Jafar Al Souz, Daniel Williams, Rahul Kamdar, Olena Kamenyeva, Juraj Kabat, Ethan Shevach, Billur Akkaya
Publikováno v:
eLife, Vol 12 (2024)
Delineating the complex network of interactions between antigen-specific T cells and antigen presenting cells (APCs) is crucial for effective precision therapies against cancer, chronic infections, and autoimmunity. However, the existing arsenal for
Externí odkaz:
https://doaj.org/article/fa37a84c2daa401bbccbb746c12a3d89
Autor:
Clare K. Cimperman, Mirna Pena, Sohret M. Gokcek, Brandon P. Theall, Meha V. Patel, Anisha Sharma, ChenFeng Qi, Daniel Sturdevant, Louis H. Miller, Patrick L. Collins, Susan K. Pierce, Munir Akkaya
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Cerebral malaria (CM), the deadliest complication of Plasmodium infection, is a complex and unpredictable disease. However, our understanding of the host and parasite factors that cause CM is limited. Using a mouse model of CM, experimental
Externí odkaz:
https://doaj.org/article/3261caae55db47f9969e701fac6f0d4d
Autor:
Alfonso S Gozalo, Patricia M Zerfas, Jing Qin, Derron A Alves, Munir Akkaya, Mirna Y Peña, William R Elkins
Publikováno v:
Comparative Medicine. 73:109-119
C57BL/6J (B6) mice are commonly affected by ulcerative dermatitis (UD), a disease of unknown etiology with poor response to treatment. To study the possible role of diet in UD, we compared skin changes in B6 female mice fed a high-fat diet with those
Autor:
Clare K. Cimperman, Mirna Pena, Sohret M. Gokcek, Brandon P. Theall, Meha V. Patel, Anisha Sharma, ChenFeng Qi, Daniel Sturdevant, Louis H. Miller, Patrick L Collins, Susan K. Pierce, Munir Akkaya
Cerebral Malaria (CM), the deadliest complication ofPlasmodiuminfection, is a complex and unpredictable disease. However, our understanding of the host and parasite factors that cause CM is limited. Using a mouse model of CM, experimental CM (ECM), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48bc41d815ba2f783e94cf8e4f98409
https://doi.org/10.1101/2022.11.23.517617
https://doi.org/10.1101/2022.11.23.517617
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2497
During lymphocyte maturation and differentiation, cells undergo a series of proliferative stages interrupted with stages of low activity. The rapid proliferation stages are marked by changes in metabolic outputs-adapting to energy demands by either h
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623084
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff5dbf494dd146f1424b3dd2aedcbc1
https://doi.org/10.1007/978-1-0716-2309-1_17
https://doi.org/10.1007/978-1-0716-2309-1_17
Publikováno v:
Nature Reviews. Immunology
Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such protection is mediated, in large part, by two main B cell memory ‘walls’ — namely, long-lived plasma cells and memory B cells. The cellular and mole
Inhibiting the Mammalian Target of Rapamycin Blocks the Development of Experimental Cerebral Malaria
Autor:
Emile B. Gordon, Geoffrey T. Hart, Tuan M. Tran, Michael Waisberg, Munir Akkaya, Jeff Skinner, Severin Zinöcker, Mirna Pena, Takele Yazew, Chen-Feng Qi, Louis H. Miller, Susan K. Pierce
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT Malaria is an infectious disease caused by parasites of several Plasmodium spp. Cerebral malaria (CM) is a common form of severe malaria resulting in nearly 700,000 deaths each year in Africa alone. At present, there is no adjunctive therapy
Externí odkaz:
https://doaj.org/article/d9d29f731e7d438284e52153462fb045
Autor:
Munir Akkaya
Publikováno v:
Immunometabolism
Recent advancements in the field of B cell immunometabolism have provided mechanistic insights to B cell activation and fate determination. Here, in this short article, I will explain the main principles of our novel metabolic clock model and how it
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2304
The identification of cellular changes that accompany immune activation has been a long-standing interest for immunologists. Among these, alterations in the metabolic states of these cells have gained particular attention in the last decade due to th