Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Munikumar Reddy Doddareddy"'
Autor:
Namfon Pantarat, Danuta S. Kalinowski, David E. Hibbs, Des R. Richardson, Munikumar Reddy Doddareddy, Jennifer Ong, Darius J.R. Lane, Vera Richardson, Michael L.-H. Huang, Angelica M. Merlot, Ashleigh M. Fordham, Sumit Sahni
Publikováno v:
Oncotarget
// Angelica M. Merlot 1 , Sumit Sahni 1 , Darius J.R. Lane 1 , Ashleigh M. Fordham 1 , Namfon Pantarat 1 , David E. Hibbs 2 , Vera Richardson 1 , Munikumar R. Doddareddy 2 , Jennifer A. Ong 2 , Michael L.H. Huang 1 , Des R. Richardson 1,* and Danuta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afc1732400dd9803a1a53260d1ad50b
https://doi.org/10.18632/oncotarget.3606
https://doi.org/10.18632/oncotarget.3606
Autor:
Shalini Srivastava, Pratik M. Oza, Rajeshwar Narlawar, Ramesh R. Mamidi, Dulal Panda, David E. Hibbs, Anusri Bhattacharya, Emma C. L. Marrs, Kishore Kunal, Paul W. Groundwater, Vivian Wan Yu Liao, John D. Perry, Munikumar Reddy Doddareddy
Publikováno v:
IndraStra Global.
Inhibition of FtsZ assembly has been found to stall bacterial cell division. Here, we report the identification of a potent carbocyclic curcumin analogue (2d) that inhibits Bacillus subtilis 168 cell proliferation by targeting the assembly of FtsZ. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ccf2ddac9cbce65234d379ccdfc7d5
https://igi.indrastra.com/items/show/54965
https://igi.indrastra.com/items/show/54965
Autor:
David E. Hibbs, Munikumar Reddy Doddareddy, Paul W. Groundwater, Azadeh Matin, Rebecca H. Roubin, Navnath Gavande, Srinivas Nammi
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:766-778
Twenty three dual PPARα and γ molecules of natural product origin, previously reported by our group, were further investigated for pan PPAR transactivation against PPARδ. The in vitro cell toxicity profile, as well as, in silico study of the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4bbdbd4b229da93be00a27febf5fa9
https://doi.org/10.1016/j.bmc.2012.11.040
https://doi.org/10.1016/j.bmc.2012.11.040
Autor:
David E. Hibbs, Veronika Bender, Eve Diefenbach, Nicholas Manolios, Munikumar Reddy Doddareddy, Marina Ali, Laura Raguine
Publikováno v:
Chemical Biology & Drug Design. 81:167-174
Core peptide is a hydrophobic peptide, the sequence of which is derived from the T-cell antigen receptor alpha-chain transmembrane region. Previous studies have shown that core peptide can inhibit T-cell-mediated immune responses both in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff398e8a1f18d1bfc0fefe9ebfc7f14
https://doi.org/10.1111/cbdd.12080
https://doi.org/10.1111/cbdd.12080
Autor:
Samuel D. Banister, Robert H. Mach, Jinquan Cui, Miral Manoli, Iman A. Moussa, Munikumar Reddy Doddareddy, Michael Kassiou
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5493-5497
Imidazolidine and 1,4-diazepane analogs of N-(2-benzofuranyl)methyl-N′-(4-alkoxybenzyl)piperazines were prepared to explore the effect of ring contraction and expansion on σ receptor affinity and subtype selectivity within a series of cyclic diami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea3b3dd4cc14552ddee23ca265367956
https://doi.org/10.1016/j.bmcl.2012.07.026
https://doi.org/10.1016/j.bmcl.2012.07.026
Publikováno v:
Bulletin of the Korean Chemical Society. 32:2008-2014
Serotonin or 5-hydroxytryptamine subtype 2C (5-HT2C) receptor belongs to class A amine subfamily of Gprotein-coupled receptor (GPCR) super family and its ligands has therapeutic promise as anti-depressant and -obesity agents. So far, bovine rhodopsin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9086b03dddb463e3c5e07966f804d3c
https://doi.org/10.5012/bkcs.2011.32.6.2008
https://doi.org/10.5012/bkcs.2011.32.6.2008
Autor:
Dhanaji Achyutrao Thorat, Tae-Joon Hong, Ji-Sook Hahn, Yong Seo Cho, Munikumar Reddy Doddareddy, Ae Nim Pae, Seon Hee Seo
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:1714-1720
Structure based drug design (SBDD) was used to discover heat shock protein 90 (HSP90) inhibitors useful in the treatment of cancer. By using the crystal structure of HSP90-ligand complex (1uyi), a docking model was prepared and was validated by exter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56c18ae312831ab2ce3075f7fe7be8f
https://doi.org/10.1016/j.bmc.2011.01.023
https://doi.org/10.1016/j.bmc.2011.01.023
Publikováno v:
ChemMedChem. 5:716-729
Ligand-based in silico hERG models were generated for 2 644 compounds using linear discriminant analysis (LDA) and support vector machines (SVM). As a result, the dataset used for the model generation is the largest publicly available (see Supporting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636e8c83e372f5d90c891d670ab20bb7
https://doi.org/10.1002/cmdc.201000024
https://doi.org/10.1002/cmdc.201000024
Autor:
Judy Lin, Rajeshwar Narlawar, Johannes Brussee, Munikumar Reddy Doddareddy, Adriaan P. IJzerman, J. Robert Lane
Publikováno v:
Journal of Medicinal Chemistry. 53:3028-3037
Many G protein-coupled receptors (GPCRs), including the adenosine A(1) receptor (A(1)AR), have been shown to be allosterically modulated by small molecule ligands. So far, in the absence of structural information, the exact location of the allosteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72ca46c41a20a50a7a64c222ac34840
https://doi.org/10.1021/jm901252a
https://doi.org/10.1021/jm901252a
Autor:
Yong Seo Cho, Ae Nim Pae, Byung Ho Lee, Munikumar Reddy Doddareddy, Kwang-Seok Oh, Shanthi Nagarajan, Hyunah Choo
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:2759-2766
Control of NF-kappaB release through the inhibition of IKKbeta has been identified as a potential target for the treatment of inflammatory and autoimmune diseases. We have employed structure based virtual screening scheme to identify lead like molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed16cddec54baa74f91927b8b98e616
https://doi.org/10.1016/j.bmc.2009.02.041
https://doi.org/10.1016/j.bmc.2009.02.041