Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Muneyuki Sakata"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Background 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) is commonly used for diagnosis of dementia because brain glucose metabolism reflects neuronal activity. However, as [18F]FDG is an analogue of glucose, accumulation of tracer in the brain
Externí odkaz:
https://doaj.org/article/ca3f76060dd741318ea6606d85db2474
Autor:
Kei Wagatsuma, Muneyuki Sakata, Kenta Miwa, Yumi Hamano, Hirofumi Kawakami, Yuto Kamitaka, Tensho Yamao, Noriaki Miyaji, Kenji Ishibashi, Tetsuro Tago, Jun Toyohara, Kenji Ishii
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-16 (2024)
Abstract Purpose Bayesian penalised likelihood (BPL) reconstruction, which incorporates point-spread-function (PSF) correction, provides higher signal-to-noise ratios and more accurate quantitation than conventional ordered subset expectation maximiz
Externí odkaz:
https://doaj.org/article/a7bcf83c9f3d45dc93081246bd589657
Autor:
Etsuko Imabayashi, Kenji Ishii, Jun Toyohara, Kei Wagatsuma, Muneyuki Sakata, Tetsuro Tago, Kenji Ishibashi, Narumi Kojima, Noriyuki Kohda, Aya M. Tokumaru, Hunkyung Kim
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Neurodegenerative changes in the preclinical stage of Alzheimer’s disease (AD) have recently been the focus of attention because they may present a range of treatment opportunities. A total of 134 elderly volunteers who lived in a local community w
Externí odkaz:
https://doaj.org/article/8107d187fdba4e08845109a1a883a7a2
Autor:
Jun Toyohara, Norihiro Harada, Takeharu Kakiuchi, Hiroyuki Ohba, Masakatsu Kanazawa, Tetsuro Tago, Muneyuki Sakata, Kiichi Ishiwata
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Introduction Increases in fasting plasma glucose (PG) levels lead to a decrease in 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) uptake in the normal brain, especially in the precuneus, resulting in an Alzheimer’s disease (AD)-like uptake pat
Externí odkaz:
https://doaj.org/article/671d05d5fcbf4c1580a1773191a3374d
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Introduction [18F]MC225 is a selective substrate for P-glycoprotein (P-gp) that has good metabolic stability and shows higher baseline uptake compared with other P-gp substrates such as (R)-[11C]Verapamil. Prior to clinical translation, it i
Externí odkaz:
https://doaj.org/article/85bc3dc1359b416aadde97599108780b
Autor:
Masahiro Mishina, Yuichi Kimura, Muneyuki Sakata, Kenji Ishii, Keiichi Oda, Jun Toyohara, Kazumi Kimura, Kiichi Ishiwata
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Adenosine A1 receptors (A1Rs) are widely distributed throughout the entire human brain, while adenosine A2A receptors (A2ARs) are present in dopamine-rich areas of the brain, such as the basal ganglia. A past study using autoradiography reported a re
Externí odkaz:
https://doaj.org/article/baaa4f876fca488898c5b13fd4940aba
Publikováno v:
Entropy, Vol 19, Iss 11, p 629 (2017)
It is known that the process of reconstruction of a Positron Emission Tomography (PET) image from sinogram data is very sensitive to measurement noises; it is still an important research topic to reconstruct PET images with high signal-to-noise ratio
Externí odkaz:
https://doaj.org/article/895f6197a7a642f6958ea30722ecd459
Autor:
Masahiro Mishina, Kiichi Ishiwata, Mika Naganawa, Yuichi Kimura, Shin Kitamura, Masahiko Suzuki, Masaya Hashimoto, Kenji Ishibashi, Keiichi Oda, Muneyuki Sakata, Makoto Hamamoto, Shiro Kobayashi, Yasuo Katayama, Kenji Ishii
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17338 (2011)
Adenosine A(2A) receptors (A2ARs) are thought to interact negatively with the dopamine D(2) receptor (D2R), so selective A2AR antagonists have attracted attention as novel treatments for Parkinson's disease (PD). However, no information about the rec
Externí odkaz:
https://doaj.org/article/069888551e134aa2826f234b749d242c
Autor:
Jun Toyohara, Kiichi Ishiwata, Muneyuki Sakata, Jin Wu, Shingo Nishiyama, Hideo Tsukada, Kenji Hashimoto
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e8961 (2010)
BackgroundThe alpha7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. The goal of this study was to evaluate the two carbon-11-labeled
Externí odkaz:
https://doaj.org/article/0de442a6025d4bf680719d77708c3e22
Autor:
Kei Wagatsuma, Kenji Ishibashi, Masashi Kameyama, Muneyuki Sakata, Kenta Miwa, Yuto Kamitaka, Kenji Ishii
Publikováno v:
Radiological Physics and Technology. 15:116-124