Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Munekiyo Kaneko"'
Publikováno v:
Thrombosis Research. 101:119-126
The potential benefits of SM-20302, (2 S )-3-(3-(4-amidinobenzoylamino)propanoylamino)-2-(4-ethyl)benzensulfonylaminopropionic acid hydrochloride, a nonpeptide GPIIb/IIIa receptor antagonist, were compared with those of aspirin and ticlopidine in a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e64d0fd89c9ef335407bacfb46c887
https://doi.org/10.1016/s0049-3848(00)00378-9
https://doi.org/10.1016/s0049-3848(00)00378-9
Autor:
Jinbao Huang, Benedict R. Lucchesi, Munekiyo Kaneko, Yoshikazu Saitoh, Wayne J. Shiu, Kumi Saito, Sam S. Rebello
Publikováno v:
Journal of Cardiovascular Pharmacology. 32:485-494
We examined the pharmacokinetic and pharmacodynamic properties of SM-20302, a GPIIb/IIIa receptor antagonist, in anesthetized dogs. SM-20302 was administered intravenously in doses of 30 (n = 2), 100 (n = 4), 300 (n = 4), and 1,000 μg/kg (n = 4). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700019c075d4700692463f4457fec336
https://doi.org/10.1097/00005344-199809000-00021
https://doi.org/10.1097/00005344-199809000-00021
Autor:
Munekiyo Kaneko, Akito Yatani, Mitsuhiro Yokoyama, Yasunori Ichikawa, Hajime Nakahara, Osamu Matsuo, Kazuki Matsui, Teruo Sakurama, Shigeru Ueshima
Publikováno v:
Journal of Cardiovascular Pharmacology. 28:571-575
Tissue-type plasminogen activator (t-PA) can occur in two different forms, single- and two-chain t-PA. Such a difference in structure of the t-PA molecule may induce different biological functions. We compared the thrombolytic efficacy of single-chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e38553fd7345edf0dcb60c0aee24370
https://doi.org/10.1097/00005344-199610000-00015
https://doi.org/10.1097/00005344-199610000-00015
Publikováno v:
Thrombosis and Haemostasis. 76:569-576
SummaryWe have studied the expression of plasminogen activator inhibitor 2 (PAI-2) in the adult mouse and during embryonic development using immunohistochemistry and the polymerase-chain reaction. Mouse PAI-2 mRNA was mainly expressed in the skin, bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1a2ea51ab22b20fc67636299914688
https://doi.org/10.1055/s-0038-1650624
https://doi.org/10.1055/s-0038-1650624
Publikováno v:
The Journal of Biochemistry. 111:244-248
We have shown that plasminogen activator inhibitor-1 (PAI-1) inhibits the fibrin binding of both the single chain and two chain forms of tissue-type plasminogen activator (tPA) through two different mechanisms. PAI-1 inhibits the finger domain-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f69561e872458ada6da6a4e7681b58c
https://doi.org/10.1093/oxfordjournals.jbchem.a123744
https://doi.org/10.1093/oxfordjournals.jbchem.a123744
Publikováno v:
Thrombosis and haemostasis. 82(6)
SummaryWe have developed a gastrointestinal hemorrhage model in mice and thereby assessed the potential risk of bleeding following administration of SM-20302, a nonpeptide GPIIb/IIIa receptor antagonist. First, SM-20302 selectively inhibited the inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9eb6173b5478e0510ac693e17b3a46
https://pubmed.ncbi.nlm.nih.gov/10613664
https://pubmed.ncbi.nlm.nih.gov/10613664
Publikováno v:
Prostaglandins. 51(2)
The antithrombotic effect of topical application of the 3-oxamethano-prostaglandin (PG) I 1 analog, SM-10902 in the microcirculation and in vitro antiplatelet functions of its active form SM-10906 were estimated in comparison with PGI 2 and PGE 1 . I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f5e9d9ca2a90449841c53a2899faa9
https://pubmed.ncbi.nlm.nih.gov/8711136
https://pubmed.ncbi.nlm.nih.gov/8711136
Publikováno v:
Biochemical and biophysical research communications. 178(3)
We have shown that synthetic peptides containing the amino acid sequence Asn-Arg-Arg-Leu, derived from the amino acid sequence of the inner loop of the kringle-2 domain of tissue-type plasminogen activator (tPA), inhibited complex formation between t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ca21b5b17727eeff5df1a30d1dc9ba
https://pubmed.ncbi.nlm.nih.gov/1908232
https://pubmed.ncbi.nlm.nih.gov/1908232
Publikováno v:
Blood & Vessel. 20:70-73
To study the susceptability of fibrin plate method for determination of t-PA activity, the activity of melanoma t-PA (mt-PA) was compared with that of recombinant t-PA (rt-PA) using the International Reference Preparation for urokinase as a standard.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a12c521fa9040f87b4a5dab238c5da7
https://doi.org/10.2491/jjsth1970.20.70
https://doi.org/10.2491/jjsth1970.20.70
Autor:
Munekiyo Kaneko, Sadahiko Ishibashi
Publikováno v:
Development, Growth and Differentiation. 27:745-749
The changes in activities and intracellular locations of glycerol kinase in rat brain and liver during development were compared. Glycerol kinase activity was consistently much higher in the liver than in the brain from just before the birth to the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8668733cc4ecf994b6eef2dc2124e962
https://doi.org/10.1111/j.1440-169x.1985.00745.x
https://doi.org/10.1111/j.1440-169x.1985.00745.x