Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Muneki Miura"'
Autor:
Kumiyo Oba, Ri Ichiro Kohno, Yasuaki Hata, Tatsuro Ishibashi, Shintaro Nakao, Yukio Sassa, Alexander Schering, Muneki Miura, Takeshi Kita
Publikováno v:
British Journal of Ophthalmology. 95:261-265
Background/aim Tumour necrosis factor-a (TNFa )i s an inflammatory cytokine that is upregulated in various vitreoretinal diseases including uveitis and diabetic retinopathy. Recently, our studies have indicated that hyalocytes contribute to the patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e787ed8166f9866d25041c2866f6afe5
https://doi.org/10.1136/bjo.2010.190322
https://doi.org/10.1136/bjo.2010.190322
Autor:
Shintaro Nakao, Souska Zandi, Yasuaki Hata, Tatsuro Ishibashi, Shuhei Kawahara, Muneki Miura, Ryoichi Arita, L. Almulki, Hiroaki Shimokawa, Ali Hafezi-Moghadam, Faryan Tayyari, Takeshi Kita
Publikováno v:
Diabetes
OBJECTIVE—Leukocyte adhesion in retinal microvasuculature substantially contributes to diabetic retinopathy. Involvement of the Rho/Rho kinase (ROCK) pathway in diabetic microvasculopathy and therapeutic potential of fasudil, a selective ROCK inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77e709d0b03fac291e164d76b4ab8de
http://europepmc.org/articles/PMC2606876
http://europepmc.org/articles/PMC2606876
Autor:
Hiroshi Enaida, Muneki Miura, Tadahisa Kagimoto, Ryoichi Arita, Yoshinobu Goto, Takeshi Kita, Tatsuro Ishibashi, Yasuaki Hata, Ali Hafezi-Moghadam, Shuhei Kawahara, Shintaro Nakao, Yasutaka Mochizuki
Publikováno v:
Diabetes
OBJECTIVE—Despite tremendous progress in vitreoretinal surgery, certain postsurgical complications limit the success in the treatment of proliferative vitreoretinal diseases (PVDs), such as proliferative diabetic retinopathy (PDR) and proliferative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8dba30e97021237f056bd986433683
https://doi.org/10.2337/db08-0302
https://doi.org/10.2337/db08-0302
Autor:
Yusuke N. Kimura, Shintaro Nakao, Ali Hafezi-Moghadam, Kousuke Noda, Tatsuro Ishibashi, Muneki Miura, Shuhei Kawahara, Toshio Hisatomi, Yiping Jin, Toru Nakazawa, Reza Dana, Takeshi Kita, Mayumi Ono, Yasuaki Hata, Michihiko Kuwano
Publikováno v:
The American Journal of Pathology. 171:1058-1065
Dexamethasone, a synthetic corticosteroid, is widely used as a potent anti-inflammatory drug in various diseases including corneal angiogenesis. However, dexamethasone's impact on interleukin (IL)-1β-dependent inflammatory angiogenesis is unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70215280de83b55e75fa174a8e3027bc
https://doi.org/10.2353/ajpath.2007.070172
https://doi.org/10.2353/ajpath.2007.070172
Publikováno v:
Diabetes. 56:1421-1428
Connective tissue growth factor (CTGF) level is elevated in eyes with proliferative vitreoretinal diseases, such as proliferative diabetic retinopathy and proliferative vitreoretinopathy (PVR), as we previously reported, but its functional characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81800b79a391143412ff9e9b67e03fcf
https://doi.org/10.2337/db06-1644
https://doi.org/10.2337/db06-1644
Autor:
Shintaro Nakao, Yoshihiro Noda, Yasuaki Hata, Hiroaki Shimokawa, Tatsuro Ishibashi, Takeshi Kita, Muneki Miura, Kumiko Kano
Publikováno v:
Diabetes. 56:231-238
The critical association of connective tissue growth factor (CTGF), which is thought to be one of the downstream mediators of transforming growth factor-β (TGF-β), with vitreoretinal diseases remains to be clarified. In the current study, we first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecdc7f5aa70e04dcfcb9e90221244618
https://doi.org/10.2337/db06-0581
https://doi.org/10.2337/db06-0581
Autor:
Hiroshi Enaida, Yoshinobu Goto, Tatsuro Ishibashi, Yukio Sassa, Yasuaki Hata, Toshio Hisatomi, Muneki Miura, Akifumi Ueno
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 245:1019-1025
To examine the effects of intravitreal fluorometholone acetate (FMT) on the morphology and function of the retina and to investigate its possible use for vitreous surgery.Brown Norway rat eyes (n = 6, 12 groups) were injected with 0.05 ml of SF6 gas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca9f4925ddb68e06dd8533da7269c17
https://doi.org/10.1007/s00417-006-0499-8
https://doi.org/10.1007/s00417-006-0499-8
Autor:
Kimihiko Fujisawa, Takeshi Kita, Yasuaki Hata, Muneki Miura, Tatsuro Ishibashi, Kumiko Hirayama, Yoshihiro Noda, Hiroaki Shimokawa
Publikováno v:
Experimental Eye Research. 82:849-859
Retinal pigment epithelial cells (RPEs) are thought to be one of the main components of fibrous membrane observed in eyes with proliferative vitreo-retinopathy. We investigated the signalling mechanisms of TGF-beta2-dependent collagen gel contraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ed964e92a92c7d128482fbd7ec5054
https://doi.org/10.1016/j.exer.2005.09.024
https://doi.org/10.1016/j.exer.2005.09.024
Autor:
Ri Ichiro Kohno, Yasuaki Hata, Muneki Miura, Ryo Asato, Shintaro Nakao, Ryoichi Arita, Tatsuro Ishibashi, Shuhei Kawahara, Takeshi Kita, Kumiyo Oba
Publikováno v:
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. 248(5)
While statins have an anti-angiogenic property, their underlying mechanisms are not fully understood. We investigated intracellular mechanisms of simvastatin-mediated reduction in VEGF-induced signalings.The effects of simvastatin on cell proliferati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5bc3b629fefc4c7d0e4277366a7dc0
https://pubmed.ncbi.nlm.nih.gov/20155363
https://pubmed.ncbi.nlm.nih.gov/20155363
Autor:
Takeshi Kita, Kumiko Kano, Shintaro Nakao, Yukio Sassa, J L Shih, Ryoichi Arita, Muneki Miura, Tatsuro Ishibashi, Yasuaki Hata, Shuhei Kawahara
Publikováno v:
The British journal of ophthalmology. 92(11)
Tumour necrosis factor-alpha (TNF-alpha) is one of the major inflammatory cytokines involved in the pathogenesis of various vitreoretinal diseases. The authors investigated the effect of hypoxia, TNF-alpha and dexamethasone on vascular endothelial gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18eb0f7cd3cecc4f64a2661b66b1987
https://pubmed.ncbi.nlm.nih.gov/18952656
https://pubmed.ncbi.nlm.nih.gov/18952656