Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Munehiro Nakata"'
Autor:
Hirota Yokoyama, Koichiro Tateishi, Yurie Baba, Akina Kobayashi, Manami Hashimoto, Shion Fukuda, Hinano Yamao, Taiga Maruyama, Munehiro Nakata, Misao Matsushita
Publikováno v:
Bioscience trends.
Thrombomodulin (TM) is a transmembrane protein that plays an important role in regulating the coagulation system by acting as a cofactor for thrombin in protein C activation. Additionally, TM is involved in inflammation. Previous studies have shown t
Publikováno v:
BioScience Trends. 13:86-90
The current study determined the structure of a hemolytic compound found in an extract from the fruiting bodies of the edible mushroom Hypsizygus marmoreus when its pH was lowered. The hemolytic compound was purified using the modified Bligh and Dyer
Publikováno v:
BioScience Trends. 12:325-329
The current study found that an extract from the fruiting bodies of the edible mushroom Hypsizygus marmoreus exhibited hemolytic activity against sheep red blood cells when its pH was lowered. Although hemolytic activity was not detected when an extr
Autor:
Munehiro Nakata1, Wei Tang2, Yoko Fujita-Yamaguchi1,3, Shuya Mori1, Yo Kamoshida1, Bo Gao3, Shota Kawaguchi1
Publikováno v:
BioScience Trends. Aug2015, Vol. 9 Issue 4, p266-269. 4p.
Publikováno v:
Bioscience trends. 12(3)
The current study found that an extract from the fruiting bodies of the edible mushroom Hypsizygus marmoreus exhibited hemolytic activity against sheep red blood cells when its pH was lowered. Although hemolytic activity was not detected when an extr
Autor:
Kenzui Taniue, Hiroshi Nakada, Kazuo Yamamoto, Yukiko Yajima, Tetsu Akiyama, Yoko Fujita-Yamaguchi, Munehiro Nakata, Fumie Oura
Publikováno v:
BioScience Trends. 9:49-55
Anti-Tn antigen MLS128 monoclonal antibody was produced two decades ago by immunizing mice with "cancerous antigens" derived from LS180 colon cancer cells. Previous studies demonstrated that MLS128 bound to 110 kDa glycoprotein (GP) in colon cancer c
Autor:
Mioto Yoshida, Yoko Fujita-Yamaguchi, Yo Kamoshida, Munehiro Nakata, Kyohei Fukuda, Taisuke Kurokawa
Publikováno v:
BioScience Trends. 8:212-216
This study sought to devise a way to assess the infiltration of cancer cells in model stromal tissues. Human breast carcinoma MDA-MB-231 cells were loaded on the surface of a type I collagen gel in the well of 8-well chamber slide and allowed to migr
Autor:
Munehiro Nakata, Saeko Ichimi, Hirokazu Miyai, Yoko Fujita-Yamaguchi, Chuan Luo, Shota Kawaguchi, Tomomi Nonaka, Akito Inamura, Shunki Nomoto, Wei Tang, Ayami Oikawa, Bo Gao
Publikováno v:
Drug discoveriestherapeutics. 9(6)
An aqueous extract from toad skin, cinobufacini, has been known to possess anticancer ability. The present study examined effect of toad skin extract on activity of gelatinases including matrix metalloproteinases-2 and -9 which play an important role
Autor:
Norihiro Kokudo, Wei Tang, Sumihito Tamura, Fanghua Qi, Anyuan Li, Munehiro Nakata, Yoshinori Inagaki
Publikováno v:
International Immunopharmacology. 11:342-349
The skin of the toad Bufo bufo gargarizans Cantor is known to be rich in bufadienolides, peptides and alkaloids. It has been found to be a source of some extracts and biologically active compounds with antitumor activity. Cinobufacini (Huachansu), a
Autor:
Tomoyuki Koizumi, Miyo Kimura, Kazuo Yamamoto, Tomohiro Goto, Wei Zhang, Hiroya Ohshima, Hiroyuki Sakaue, Yoko Fujita-Yamaguchi, Yasunobu Tsuchida, Takumi Kojima, Munehiro Nakata, Noriyuki Yuasa, Keiko Sakai, Ayano Matsumoto-Takasaki
Publikováno v:
Journal of Biological Chemistry. 285:30587-30597
Anti-mannotriose (Man3) antibodies were previously isolated from a Keio phage library displaying human single chain variable fragments (scFvs) using a neoglycolipid, Man3- dipalmitoylphosphatidylethanolamine. Of three genes constructed, the 5A3 clone