Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Munehiro Kitada"'
Autor:
Keiji Shimada, Keizo Kanasaki, Makoto Kato, Yoshio Ogura, Yuta Takagaki, Itaru Monno, Taro Hirai, Munehiro Kitada, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 6, Pp 955-964 (2022)
Abstract Aims/Introduction Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have been shown to display excellent renoprotective effects in diabetic kidney disease with macroalbuminuria/proteinuria. Regarding the renoprotective mechanism of SGLT2i
Externí odkaz:
https://doaj.org/article/0b184aa20b184b93b6ab0ac42f9c8f01
Autor:
Taro Hirai, Munehiro Kitada, Itaru Monno, Erina Oda, Yoshihiro Hayashi, Keiji Shimada, Yuta Takagaki, Yoshio Ogura, Mizue Fujii, Kazunori Konishi, Masaru Sakurai, Atsushi Nakagawa, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 12, Iss 9, Pp 1577-1585 (2021)
Abstract Aims/Introduction The aim of this study was to elucidate whether sodium–glucose cotransporter 2 inhibitors (SGLT2is) treatment has any renoprotective effect for type 2 diabetes mellitus patients with an estimated glomerular filtration rate
Externí odkaz:
https://doaj.org/article/b15014c99b144c01b71d312f5adb526f
Autor:
Yuiko Mizunuma, Keizo Kanasaki, Kyoko Nitta, Yuka Nakamura, Yasuhito Ishigaki, Yuta Takagaki, Munehiro Kitada, Shaolan Li, Haijie Liu, Jinpeng Li, Isao Usui, Yoshimasa Aso, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 6, Pp 1470-1481 (2020)
Abstract Aims/Introduction To establish novel therapies to combat diabetic kidney disease, a human disease‐relevant animal model is essential. However, a type 2 diabetic mouse model presenting progressive kidney fibrosis has not yet been establishe
Externí odkaz:
https://doaj.org/article/d22e85eb36dd4f09a088a6c5e1641441
Autor:
Taro Hirai, Munehiro Kitada, Yoshihiro Hayashi, Itaru Monno, Yuta Takagaki, Keiji Shimada, Yoshio Ogura, Mizue Fujii, Kazunori Konishi, Atsushi Nakagawa, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 5, Pp 1359-1362 (2020)
Abstract A 58‐year‐old women who was diagnosed with type 2 diabetes 20 years earlier had been treated with antidiabetic medicines since she was aged 40 years. After sodium–glucose cotransporter 2 inhibitors administration, her bodyweight rapidl
Externí odkaz:
https://doaj.org/article/7b3332833085472ea452eefe24ff0be1
Publikováno v:
Cells, Vol 12, Iss 4, p 595 (2023)
Aging is a major risk factor for the leading causes of mortality, and the incidence of age-related diseases including cardiovascular disease, kidney disease and metabolic disease increases with age. NAD+ is a classic coenzyme that exists in all speci
Externí odkaz:
https://doaj.org/article/f8443d41f3ad4ac8bc99d85a30f653f6
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
The redox reaction and energy metabolism status in mitochondria is involved in the pathogenesis of metabolic related disorder in kidney including diabetic kidney disease (DKD). Nicotinamide adenine dinucleotide (NAD+) is a cofactor for redox reaction
Externí odkaz:
https://doaj.org/article/289b215ad6384c3096c903463668a5ba
Publikováno v:
FEBS Open Bio, Vol 9, Iss 5, Pp 1029-1038 (2019)
Endothelial–mesenchymal transition (EndMT) has emerged as an essential bioprocess responsible for the development of organ fibrosis. We have previously reported that fibroblast growth factor receptor 1 (FGFR1) is involved in the anti‐EndMT effect
Externí odkaz:
https://doaj.org/article/96c5663bd3ec4ce28383f6cdf224dc12
Autor:
Munehiro Kitada, Yoshio Ogura, Kyoko Nitta, Mizue Fujii, Keizo Kanasaki, Kazunori Konishi, Yasuo Iida, Atsushi Nakagawa, Daisuke Koya
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 3, Pp 706-713 (2019)
Abstract Aims/Introduction The objective of the present study was to elucidate the effect of switching to teneligliptin from other dipeptidyl peptidase‐4 (DPP‐4) inhibitors on glucose control and renoprotection in type 2 diabetes mellitus patient
Externí odkaz:
https://doaj.org/article/4ed6ef7c1b2545df8e9b706fff5a7172
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 632-640 (2019)
Lifespan and metabolic health are influenced by dietary nutrients. Recent studies show that a reduced protein intake or low-protein/high-carbohydrate diet plays a critical role in longevity/metabolic health. Additionally, specific amino acids (AAs),
Externí odkaz:
https://doaj.org/article/191377d28ec040dbb99375c5ac14b7f0
Autor:
Swayam Prakash Srivastava, Jinpeng Li, Yuta Takagaki, Munehiro Kitada, Julie E. Goodwin, Keizo Kanasaki, Daisuke Koya
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102390- (2021)
Summary: Defects in endothelial cells cause deterioration in kidney function and structure. Here, we found that endothelial SIRT3 regulates metabolic reprogramming and fibrogenesis in the kidneys of diabetic mice. By analyzing, gain of function of th
Externí odkaz:
https://doaj.org/article/57d3ce316e674bdaba44f3e524675baa