Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Munefumi Tokugawa"'
Publikováno v:
SYNLETT. 28(No. 15):2014-2017
The Mitsunobu reaction has emerged as an important alternative for the preparation of synthetic 2′-deoxynucleosides, which have various biological and biotechnological applications. In this work, the Mitsunobu-based synthesis of 2′-deoxynucleosid
Autor:
Mitsuo Sekine, Jan Christian Canggadibrata, L. Marcus Wilhelmsson, Takashi Kanamori, Morten Grøtli, Yoshiaki Masaki, Kazuhei Kaneko, Munefumi Tokugawa, Kohji Seio, Takashi Shiozawa
Publikováno v:
Chemical Communications. 52:3809-3812
7-(Benzofuran-2-yl)-7-deazadeoxyguanosine ((BF)dG) was synthesized and incorporated into an oligodeoxynucleotide (ODN). The single-stranded ODN containing (BF)dG shows 91-fold fluorescence enhancement upon binding of single-strand DNA binding protein
Autor:
Akihiro Ohkubo, Mitsuo Sekine, Masanori Saito, Takashi Kanamori, Kazuhei Kaneko, Yoshiaki Masaki, Munefumi Tokugawa, Kohji Seio
Publikováno v:
CHEM. LETT.. 44:64-66
In order to develop fluorescent guanine analogs having substitutions at the 7-positions, 7-(benzofuran-2-yl)-7-deazahypoxanthine (1a) and 7-(benzofuran-2-yl)-7-deazaguanine (1b), were synthesized f...
Autor:
Eric Gloaguen, Munefumi Tokugawa, Kohji Seio, Mitsuo Sekine, Yoshiaki Masaki, Hiroyuki Saigusa, Shun-ichi Ishiuchi, Hiroya Asami, Michel Mons, Masaaki Fujii
Publikováno v:
Journal of Physical Chemistry A
Journal of Physical Chemistry A, American Chemical Society, 2016, 120, pp.2179−2184. ⟨10.1021/acs.jpca.6b01194⟩
Journal of Physical Chemistry A, 2016, 120, pp.2179−2184. ⟨10.1021/acs.jpca.6b01194⟩
Journal of Physical Chemistry A, American Chemical Society, 2016, 120, pp.2179−2184. ⟨10.1021/acs.jpca.6b01194⟩
Journal of Physical Chemistry A, 2016, 120, pp.2179−2184. ⟨10.1021/acs.jpca.6b01194⟩
International audience; The ultrafast deactivation processes in the excited state of biomolecules, such as the most stable tautomers of guanine, forbid any state-of-the-art gas phase spectroscopic studies on these species with nanosecond lasers. This
Publikováno v:
ChemInform. 45
Autor:
Munefumi Tokugawa, Kohji Seio, Hirosuke Tsunoda, Akihiro Ohkubo, Hiroki Ohzeki, Yoshiaki Masaki, Takashi Kanamori, Mitsuo Sekine
Publikováno v:
Bioorganicmedicinal chemistry. 21(11)
Single- and double-stranded oligodeoxynucleotides (ODNs) incorporating both 2-aminopurine (2AP) and an indole-fused cytosine analog (PPI) were prepared and studied for their fluorescence properties. PPI and 2AP can be excited simultaneously by irradi
Autor:
Hirosuke Tsunoda, Mitsuo Sekine, Akihiro Ohkubo, Munefumi Tokugawa, Kohji Seio, Fumio Arisaka
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(24)
The structural properties of a DNA/RNA duplex having a pyrene residue at the 5′ end of DNA and a G-rich single strand region at the 3′ end of RNA were studied in detail. Fluorescence and ultracentrifugation analyses indicated the formation of a c
Autor:
Akihiro Ohkubo, Hirosuke Tsunoda, Takashi Kanamori, Mitsuo Sekine, Munefumi Tokugawa, Kohji Seio
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(7)
2′- O -[ N -(4-Aminobutylcarbamoyl)]uridine (U abcm ) was synthesized and incorporated into oligonucleotides. The oligonucleotides incorporating U abcm formed more stable duplexes with their complementary and mismatched RNAs than those containing 2
Publikováno v:
Synlett; 2017, Vol. 28 Issue 15, p2014-2017, 4p
Autor:
Hiroya Asami, Munefumi Tokugawa, Yoshiaki Masaki, Shun-ichi Ishiuchi, Gloaguen, Eric, Kohji Seio, Hiroyuki Saigusa, Masaaki Fujii, Mitsuo Sekine, Mons, Michel
Publikováno v:
Journal of Physical Chemistry A; Apr2016, Vol. 120 Issue 14, p2179-2184, 6p