HIV-1 DIS stem loop forms an obligatory bent kissing intermediate in the dimerization pathway

Autor: Mundigala, Hansini, Michaux, Jonathan B., Feig, Andrew L., Ennifar, Eric, Rueda, David

Publikováno v: Nucleic Acids Research

The HIV-1 dimerization initiation sequence (DIS) is a conserved palindrome in the apical loop of a conserved hairpin motif in the 5'-untranslated region of its RNA genome. DIS hairpin plays an important role in genome dimerization by forming a 'kissi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d93b2a6ee44f33883989c98812a902e5
http://hdl.handle.net/10044/1/14747

HIV-1 DIS stem loop forms an obligatory bent kissing intermediate in the dimerization pathway.

Autor: Mundigala H; Department of Chemistry, Wayne State University, Detroit, MI 48236, USA., Michaux JB; Department of Chemistry, Wayne State University, Detroit, MI 48236, USA., Feig AL; Department of Chemistry, Wayne State University, Detroit, MI 48236, USA david.rueda@imperial.ac.uk., Ennifar E; Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire du CNRS, F-67084 Strasbourg, France david.rueda@imperial.ac.uk., Rueda D; Department of Chemistry, Wayne State University, Detroit, MI 48236, USA Department of Medicine, Section of Virology, Imperial College, London W12 0NN, UK Single Molecule Imaging Group, MRC Clinical Sciences Center, Imperial College, London W12 0NN, UK david.rueda@imperial.ac.uk.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2014 Jun; Vol. 42 (11), pp. 7281-9. Date of Electronic Publication: 2014 May 09.