Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Munaum H. Qureshi"'
Autor:
Jason S. Fell, Jianhua Bao, Kendall N. Houk, Pradipta Das, Munaum H. Qureshi, Jon T. Njardarson, Michael D. Delost
Publikováno v:
Journal of the American Chemical Society. 143:5793-5804
We report a dramatic effect on product outcomes of the lithium ion enabled amino-Cope-like anionic asymmetric cascade when different γ-dienolate heteroatom substituents are employed. For dienolates with azide, thiomethyl, and trifluoromethylthiol su
Autor:
Kevin A. Scott, Jeffrey R. Groch, Jianhua Bao, Christopher M. Marshall, Rachel A. Allen, Steven J. Nick, Nicholas R. Lauta, Ryan E. Williams, Munaum H. Qureshi, Michael D. Delost, Jon T. Njardarson
Publikováno v:
Tetrahedron. 126:133062
Publikováno v:
Journal of medicinal chemistry. 62(9)
Combination drugs are an important class of US FDA approved pharmaceuticals. These drugs have been on a continuous growth trajectory since the first combination drugs were approved in the 1940s. In this Perspective, we report the first comprehensive
Autor:
Shanzhong Gong, Sylvester M. Greer, Meredith K Purchal, Radhika Mehta, Emily L. Que, Chinh Q. Ngo, Munaum H Qureshi
Publikováno v:
Chemical communications (Cambridge, England). 54(43)
We report the synthesis and application of a small molecule probe for carbonic anhydrase (CA) to track holo-CA in cell lysates and live-cell models of zinc dyshomeostasis. The probe displays a 12-fold increase in fluorescence upon binding to bovine C