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Autor:
James B. McMahon, Sam Thompson, Kristina M. Cook, Peter T. Seden, Rok Sekirnik, Kelie M. Reece, Adam P. Hardy, Tawnya C. McKee, Christopher J. Schofield, William D. Figg, Madura K P Jayatunga, Mun C hiang Chan, Andrew D. Hamilton
Publikováno v:
European Journal of Medicinal Chemistry. 94:509-516
Protein-protein interactions between the hypoxia inducible transcription factor (HIF) and the transcriptional coactivators p300/CBP are potential cancer targets due to their role in the hypoxic response. A natural product based screen led to the iden