Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.

Autor: Makhaeva GF; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Kovaleva NV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Rudakova EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Boltneva NP; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Lushchekina SV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia., Astakhova TY; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia., Timokhina EN; Emanuel Institute of Biochemical Physics Russian Academy of Sciences, Moscow 119334, Russia., Serkov IV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Proshin AN; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Soldatova YV; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Poletaeva DA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Faingold II; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Mumyatova VA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Terentiev AA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Radchenko EV; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Department of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia., Palyulin VA; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia.; Department of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia., Bachurin SO; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka 142432, Russia., Richardson RJ; Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.; Center of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.; Michigan Institute for Computational Discovery and Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 09; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 09.

Novel Type of Tetranitrosyl Iron Salt: Synthesis, Structure and Antibacterial Activity of Complex [FeL' 2 (NO) 2 ][FeL'L"(NO) 2 ] with L'-thiobenzamide and L"-thiosulfate.

Autor: Sanina NA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia.; Faculty of Fundamental Physical-Chemical Engineering, M.V. Lomonosov Moscow State University, 1/51 Leninskie Gory, 119991 Moscow, Russia.; Scientific and Educational Center in Chernogolovka, Medical-Biological Institute, Moscow Regional State University, 24, Vera Voloshina Street, 141014 Mytischi, Russia., Starostina AA; Faculty of Fundamental Physical-Chemical Engineering, M.V. Lomonosov Moscow State University, 1/51 Leninskie Gory, 119991 Moscow, Russia., Utenyshev AN; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia., Dorovatovskii PV; National Research Centre 'Kurchatov Institute', 1 Acad. Kurchatov Square, 123182 Moscow, Russia., Emel'yanova NS; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia.; Faculty of Fundamental Physical-Chemical Engineering, M.V. Lomonosov Moscow State University, 1/51 Leninskie Gory, 119991 Moscow, Russia., Krapivin VB; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia., Luzhkov VB; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia.; Faculty of Fundamental Physical-Chemical Engineering, M.V. Lomonosov Moscow State University, 1/51 Leninskie Gory, 119991 Moscow, Russia., Mumyatova VA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia., Balakina AA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia., Terentiev AA; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia.; Faculty of Fundamental Physical-Chemical Engineering, M.V. Lomonosov Moscow State University, 1/51 Leninskie Gory, 119991 Moscow, Russia.; Scientific and Educational Center in Chernogolovka, Medical-Biological Institute, Moscow Regional State University, 24, Vera Voloshina Street, 141014 Mytischi, Russia., Aldoshin SM; Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, RAS, 1, Acad. Semenov Av., 142432 Chernogolovka, Russia.; Faculty of Fundamental Physical-Chemical Engineering, M.V. Lomonosov Moscow State University, 1/51 Leninskie Gory, 119991 Moscow, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 14; Vol. 27 (20). Date of Electronic Publication: 2022 Oct 14.

Iso-octenidine: Promising Octenidine Analogue with Improved Solubility.

Autor: Yakuschenko IK; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Pozdeeva NN; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Mumyatova VA; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Terentiev AA; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation., Gadomsky SY; Institute of Problems of Chemical Physics of the Russian Academy of Sciences, 142432 Chernogolovka, Moscow Region, Russian Federation.

Publikováno v: Current organic synthesis [Curr Org Synth] 2021; Vol. 18 (5), pp. 443-445.

Influence of Tumor Suppressor p53 Functioning on the Expression of Antioxidant System Genes under the Action of Cytotoxic Compounds.

Autor: Mumyatova VA; Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia. vmumyatova@bk.ru.; Scientific and Educational Center in Chernogolovka of Moscow Region State University, Mytishchi, Moscow region, Russia. vmumyatova@bk.ru., Balakina AA; Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.; Scientific and Educational Center in Chernogolovka of Moscow Region State University, Mytishchi, Moscow region, Russia., Lapshina MA; Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.; Scientific and Educational Center in Chernogolovka of Moscow Region State University, Mytishchi, Moscow region, Russia., Sen' VD; Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia., Kornev AB; Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia., Terent'ev AA; Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.; M. V. Lomonosov Moscow State University, Moscow, Russia.; Scientific and Educational Center in Chernogolovka of Moscow Region State University, Mytishchi, Moscow region, Russia.

Publikováno v: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2020 May; Vol. 169 (1), pp. 169-175. Date of Electronic Publication: 2020 Jun 05.

Effect of Chitosan-(Poly)Nitroxides on Normal and Tumor Cells under Conditions of Induced Oxidative Stress.

Autor: Mumyatova VA; Institute of Problems Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia. vmumyatova@bk.ru.; P. G. Demidov Yaroslavl State University, Yaroslavl, Russia. vmumyatova@bk.ru.; Medical Chemistry Research and Education Center, Moscow Regional State University, Mytishchi, Moscow region, Russia. vmumyatova@bk.ru., Balakina AA; Institute of Problems Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.; P. G. Demidov Yaroslavl State University, Yaroslavl, Russia.; Medical Chemistry Research and Education Center, Moscow Regional State University, Mytishchi, Moscow region, Russia., Sen' VD; Institute of Problems Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.; P. G. Demidov Yaroslavl State University, Yaroslavl, Russia., Pliss EM; P. G. Demidov Yaroslavl State University, Yaroslavl, Russia., Terent'ev AA; Institute of Problems Chemical Physics, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.; P. G. Demidov Yaroslavl State University, Yaroslavl, Russia.; Medical Chemistry Research and Education Center, Moscow Regional State University, Mytishchi, Moscow region, Russia.; Faculty of Fundamental Physical and Chemical Engineering, M. V. Lomonosov Moscow State University, Moscow, Russia.

Publikováno v: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2019 Apr; Vol. 166 (6), pp. 779-784. Date of Electronic Publication: 2019 Apr 26.