Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Mumtaz Virji"'
Autor:
Matthew L. Brewer, David Dymock, R. Leo Brady, Bernhard B. Singer, Mumtaz Virji, Darryl J. Hill
Publikováno v:
Journal of Oral Microbiology, Vol 11, Iss 1 (2019)
Neisseria meningitidis, Haemophilus influenzae, and Moraxella catarrhalis are pathogenic bacteria adapted to reside on human respiratory mucosal epithelia. One common feature of these species is their ability to target members of the carcinoembryonic
Externí odkaz:
https://doaj.org/article/7f49ede41c7144dab76ae536caa2eb74
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193940 (2018)
Neisseria meningitidis is an antigenically and genetically variable Gram-negative bacterium and a causative agent of meningococcal meningitis and septicaemia. Meningococci encode many outer membrane proteins, including Opa, Opc, Msf, fHbp and NadA, i
Externí odkaz:
https://doaj.org/article/e2e38475996d471d9f2fdace200e31bf
Autor:
Darryl J Hill, Natalie J Griffiths, Elena Borodina, Clio A Andreae, Richard B Sessions, Mumtaz Virji
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0124133 (2015)
The human pathogen Neisseria meningitides (Nm) attains serum resistance via a number of mechanisms, one of which involves binding to the host complement regulator protein vitronectin. We have shown previously that the Meningococcal surface fibril (Ms
Externí odkaz:
https://doaj.org/article/b5a49fde3607460a878b1c17b8cfc3dd
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90999 (2014)
Circulating monocytes in the bloodstream typically migrate to other tissues and differentiate into tissue resident macrophages, the process being determined by the constituents of the microenvironments encountered. These may include microbes and thei
Externí odkaz:
https://doaj.org/article/f2ddf10c760144d0bb2e177f0da7d172
Autor:
Natalie J. Griffiths, Claudia Sa E Cunha, Isabel Murillo, Abdel-Rahman Youssef, Elena Borodina, Darryl J. Hill, Mumtaz Virji
Publikováno v:
VacciMonitor, Vol 18, Iss 2, Pp 88-90 (2009)
Neisseria meningitidis outer membrane (OM) adhesins, Opa and Opc are known to exert significant influence on bacterial adhesion and invasion properties. They are also likely to affect the dynamics of cellular barrier penetration as they target human
Externí odkaz:
https://doaj.org/article/5f9922fba47045a3b3a9698a25f5f3aa
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45452 (2012)
Moraxella catarrhalis (Mx) is a common cause of otitis media and exacerbation of chronic obstructive pulmonary disease, an increasing worldwide problem. Surface proteins UspA1 and UspA2 of Mx bind to a number of human receptors and may function in pa
Externí odkaz:
https://doaj.org/article/d14069ae37f04886ad883d4d7d6e8fe8
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000911 (2010)
The host vasculature is believed to constitute the principal route of dissemination of Neisseria meningitidis (Nm) throughout the body, resulting in septicaemia and meningitis in susceptible humans. In vitro, the Nm outer membrane protein Opc can enh
Externí odkaz:
https://doaj.org/article/59d45b8ca4a842baa60117b4dcab7523
Autor:
Henry K. Wong, Anna Sintsova, Mumtaz Virji, Kelly S. MacDonald, Scott D. Gray-Owen, Rupert Kaul
Publikováno v:
Infection and Immunity. 83:1372-1383
Infections by Neisseria gonorrhoeae are increasingly common, are often caused by antibiotic-resistant strains, and can result in serious and lasting sequelae, prompting the reemergence of gonococcal disease as a leading global health concern. N. gono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff44497b96701ab6949b8e41e83e2b7c
https://doi.org/10.1128/iai.03123-14
https://doi.org/10.1128/iai.03123-14
Autor:
Mumtaz Virji, Russell K. Karls, Kari L. Fine, Maureen G. Metcalfe, Frederick D. Quinn, Elizabeth White
Publikováno v:
Cellular Microbiology. 14:1402-1414
Summary Interactions between Mycobacterium tuberculosis bacilli and alveolar macrophages have been extensively characterized, while similar analyses in epithelial cells have not been performed. In this study, we microscopically examined endosomal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62962087cb3d7ac8da867a6dc2a2bc52
https://doi.org/10.1111/j.1462-5822.2012.01804.x
https://doi.org/10.1111/j.1462-5822.2012.01804.x
Autor:
Darryl J. Hill, Mumtaz Virji, Nathalie Devos, Natalie J. Griffiths, Jan Poolman, Elena Borodina, Christiane Feron, Richard B. Sessions
Publikováno v:
Molecular Microbiology. 82:1129-1149
Complement evasion is an important survival strategy of Neisseria meningitidis (Nm) during colonization and infection. Previously, we have shown that Nm Opc binds to serum vitronectin to inhibit complement-mediated killing. In this study, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd182048982df12a0cd38753ee9d9f6c
https://doi.org/10.1111/j.1365-2958.2011.07876.x
https://doi.org/10.1111/j.1365-2958.2011.07876.x