Discovery of new pyrazole-4-carboxamide analogues as potential anticancer agents targeting dual aurora kinase A and B.

Autor: Yevale D; Henan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, 450018, China; Department of Chemistry, Shri M.M Patel Institute of Sciences and Research, Kadi Sarva Vishwavidyalaya, Gandhinagar, Gujarat, 382016, India., Teraiya N; Department of Pharmaceutical Chemistry, K B Institute of Pharmaceutical Education and Research, Kadi Sarva Vishvavidhyalay, Gandhinagar, Gujarat, 382023, India., Lalwani T; Piramal Pharma Limited, Plot No. 18, Pharmaceutical Special Economic Zone, Village-Matoda, Taluka- Sanand, Ahmedabad, Gujarat, 382213, India., Dalasaniya M; Piramal Pharma Limited, Plot No. 18, Pharmaceutical Special Economic Zone, Village-Matoda, Taluka- Sanand, Ahmedabad, Gujarat, 382213, India., Patel SK; Department of Botany, Bioinformatics and Climate Change Impacts Management, School of Science, Gujarat University, Ahmedabad, Gujarat, 380009, India., Dixit N; Department of Botany, Bioinformatics and Climate Change Impacts Management, School of Science, Gujarat University, Ahmedabad, Gujarat, 380009, India., Sangani CB; Department of Chemistry, Government Science College, Sector-15, Gandhinagar, Gujarat University, Gujarat, 382016, India. Electronic address: chetansangani1986@yahoo.com., Kumar S; Department of Pharmaceutical Chemistry and Pharmacognosy, Nitte College of Pharmaceutical Sciences, Bangalore, Karnataka, 560064, India., Mulukuri NVLS; Department of Pharmaceutical Chemistry and Pharmacognosy, Nitte College of Pharmaceutical Sciences, Bangalore, Karnataka, 560064, India., Huang T; Medical School, Huanghe Science and Technology University, Zhengzhou, China., Duan YT; Henan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, 450018, China. Electronic address: duanyongtao860409@163.com., Zhang J; Henan Provincial Key Laboratory of Pediatric Hematology, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, 450018, China. Electronic address: stzhangj@263.net.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 Dec 15; Vol. 280, pp. 116917. Date of Electronic Publication: 2024 Oct 04.