Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mulu Y. Lubula"'
Autor:
Juliet O. Obi, Mulu Y. Lubula, Gabriel Cornilescu, Amy Henrickson, Kara McGuire, Chiara M. Evans, Margaret Phillips, Samuel P. Boyson, Borries Demeler, John L. Markley, Karen C. Glass
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 104-115 (2020)
Bromodomain-containing proteins are often part of chromatin-modifying complexes, and their activity can lead to altered expression of genes that drive cancer, inflammation and neurological disorders in humans. Bromodomain-PHD finger protein 1 (BRPF1)
Externí odkaz:
https://doaj.org/article/373be060f02e4b3cb3c3da481b1aace9
Autor:
Jonathan T. Lloyd, Kyle McLaughlin, Mulu Y. Lubula, Jamie C. Gay, Andrea Dest, Cong Gao, Margaret Phillips, Marco Tonelli, Gabriel Cornilescu, Matthew R. Marunde, Chiara M. Evans, Samuel P. Boyson, Samuel Carlson, Michael-Christopher Keogh, John L. Markley, Seth Frietze, Karen C. Glass
Publikováno v:
J Med Chem
Bromodomains are chromatin reader modules that recognize acetylated lysine. Different bromodomains exhibit a preference for specific patterns of lysine acetylation marks on core and variant histone proteins, however, the functional relationships that
Autor:
Mulu Y. Lubula, Margaret Phillips, Gabriel Cornilescu, Juliet O. Obi, Karen C. Glass, Samuel P. Boyson, John L. Markley, Amy Henrickson, Chiara M. Evans, Kara McGuire, Borries Demeler
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss, Pp 104-115 (2020)
Curr Res Struct Biol
Curr Res Struct Biol
Bromodomain-containing proteins are often part of chromatin-modifying complexes, and their activity can lead to altered expression of genes that drive cancer, inflammation and neurological disorders in humans. Bromodomain-PHD finger protein 1 (BRPF1)
Autor:
Karen C. Glass, Mulu Y. Lubula, Amanda Poplawski, Maksymilian Chruszcz, Samuel Carlson, Brian E. Eckenroth
Publikováno v:
FEBS Letters. 588:3844-3854
Bromodomain-PHD finger protein 1 (BRPF1) is part of the MOZ HAT complex and contains a unique combination of domains typically found in chromatin-associated factors, which include plant homeodomain (PHD) fingers, a bromodomain and a proline-tryptopha
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 70:1389-1393
The bromodomain-PHD finger protein 1 (BRPF1) is an essential subunit of the monocytic leukemia zinc (MOZ) histone acetyltransferase (HAT) complex and is required for complex formation and enzymatic activation. BRPF1 contains a structurally conserved
Autor:
Mulu Y. Lubula
Publikováno v:
The FASEB Journal. 28
Covalent modifications on histone tails play a key role in determining the outcome of many nuclear processes including transcription, DNA repair, recombination, and replication. In humans, translocation of the monocytic leukemia zinc finger (MOZ) his