Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Multivariable mendelian randomization"'
Autor:
Qiuyuan Wang, Shanjun Cai
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
PurposeAge-related macular degeneration (AMD) is the leading cause of low vision and even blindness in the elderly population worldwide. However, no studies have been conducted to analyze the causal relationship between the cathepsin family and AMD.
Externí odkaz:
https://doaj.org/article/ceebc4ed1c2f4d3aa045f9b38f944ef6
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundThe pervasive integration of digital devices into daily life has raised concerns about their potential health impacts. This study aimed to explore the causal relationships between digital device use and the risk of migraine using Mendelian
Externí odkaz:
https://doaj.org/article/4b73fe58dbb3439890de4cd17b616c1f
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
ObjectiveThe causal link between detrimental behaviors and cognitive performance remains unclear. This research seeks to investigate the causal impact of adjustable lifestyle factors on cognitive deterioration, including frequency of alcohol intake,
Externí odkaz:
https://doaj.org/article/2a5d83e7151a449381b465366b90a635
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundFew observational studies have investigated the effect of micronutrients on osteomyelitis, and these findings are limited by confounding and conflicting results. Therefore, we conducted Mendelian randomization (MR) analyses to evaluate the
Externí odkaz:
https://doaj.org/article/5c77d342da0d40c5a721277088d9a6d0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Although serum iron status and sarcopenia are closely linked, the presence of comprehensive evidence to establish a causal relationship between them remains insufficient. The objective of this study is to employ Mendelian randomization techn
Externí odkaz:
https://doaj.org/article/ed59b30efd0e44b1a02c82de65e68953
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundObservational studies have suggested an association between gut microbiota and Alzheimer’s disease (AD); however, the causal relationship remains unclear, and the role of blood metabolites in this association remains elusive.PurposeTo elu
Externí odkaz:
https://doaj.org/article/5fe78fadbd93456c8377858c4ebb635a
Autor:
Chao Tang, Rongcheng Ruan, Bingxiao Pan, Minghong Xu, Jing Huang, Zhaoying Xiong, Zhenxing Zhang
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundIt remains unclear about the pathogenesis of intracranial aneurysms (IAs) in the setting of autoimmune disorders (ADs). However, the underlying systemic inflammatory characteristics of ADs may affect IAs through shared inflammatory pathways
Externí odkaz:
https://doaj.org/article/70175de378ef4717ba77657d83890b66
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundThe observational studies investigated the impact of migraine on Alzheimer’s Disease (AD). However, these findings were limited by confounding factors and reverse causation, leading to contradictory results.MethodsWe utilized Univariable
Externí odkaz:
https://doaj.org/article/a83bb0b05be64f7aa0366028c9194b45
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32084- (2024)
Background: Cardiovascular disease (CVD) is the leading cause of death worldwide, and statin therapy is the cornerstone of atherosclerotic cardiovascular disease. However, clinical practice is unsatisfactory, and there is significant interest in the
Externí odkaz:
https://doaj.org/article/c14467607efe4f5992ccd315b3c92e87
Autor:
Chaofan Qin, Qingshuai Yu, Zhongliang Deng, You Zhang, Mingxin Chen, Xin Wang, Tao Hu, Bo Lei, Zhengjian Yan, Si Cheng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAnkylosing spondylitis (AS) is an autoimmune disease that affects millions of individuals. Immune cells have been recognized as having a crucial role in the pathogenesis of AS. However, their relationship has not been fully explored.Methods
Externí odkaz:
https://doaj.org/article/3efe2d9f0a404942a8ecd6f185e9c6b2