Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Multiple Sclerosis/metabolism"'
Publikováno v:
Seminars in immunopathology, vol. 41, no. 6, pp. 711-726
Multiple sclerosis (MS) is a frequent autoimmune demyelinating disease of the central nervous system (CNS). There are three clinical forms described: relapsing-remitting multiple sclerosis (RRMS), the most common initial presentation (85%) among whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::21538342bf631e9837fa1cc7649579b2
https://serval.unil.ch/notice/serval:BIB_76A58CE69860
https://serval.unil.ch/notice/serval:BIB_76A58CE69860
Autor:
Mahdia Benkhoucha, Mashal Claude Ahmed, Dominique Baeten, Romain Marignier, Jose Boucraut, Olivier Casez, Michael Hahne, Jean Boutonnat, Corinne Sonrier, Benoit Manfroi, Laurie Baert, Patrice N. Marche, Nathalie Sturm, Marine Tessier, Patrice H. Lalive, Romain R. Vivès, Bertrand Huard, Cyril Rivat, Catherine Ghezzi, Hans Lassmann, Pascal Schneider, Natalia Popa, Gilda Raguenez, Alexis Broisat, Hugues Lortat-Jacob, Mitra Ahmadi
Publikováno v:
Annals of Neurology
Annals of Neurology, Wiley, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩
Annals of neurology, vol. 85, no. 3, pp. 406-420
Annals of neurology, 85(3), 406-420. John Wiley and Sons Inc.
Annals of Neurology, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩
Annals of Neurology, Wiley, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩
Annals of neurology, vol. 85, no. 3, pp. 406-420
Annals of neurology, 85(3), 406-420. John Wiley and Sons Inc.
Annals of Neurology, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩
International audience; OBJECTIVE:The two related tumor necrosis factor members a proliferation-inducing ligand (APRIL) and B-cell activation factor (BAFF) are currently targeted in autoimmune diseases as B-cell regulators. In multiple sclerosis (MS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64212102082e58fcca9193ce04f096a3
https://www.hal.inserm.fr/inserm-02332844
https://www.hal.inserm.fr/inserm-02332844
Autor:
Amandine Mathias, Andreas W. Sailer, Renaud Du Pasquier, Caroline Pot, Aurélie Sarah Clottu, Jorg Dieter Seebach, Myriam Schluep
Publikováno v:
Cell Reports, Vol. 18, No 1 (2017) pp. 213-224
Cell reports, vol. 18, no. 1, pp. 213-224
Cell reports, vol. 18, no. 1, pp. 213-224
The interaction between oxysterols and the G protein-coupled receptor Epstein-Barr virus-induced gene 2 (EBI2) fine-tunes immune cell migration, a mechanism efficiently targeted by several disease-modifying treatments developed to treat multiple scle
Autor:
Volodymyr Tkachenko, Serhiy Souchelnytskyi, Tetyana Nehrych, Yuriy Kit, Severyn Myronovkij, Nazar Negrych, Rostyslav Stoika
Publikováno v:
Protein & Peptide Letters. 23:808-811
Monitoring of multiple sclerosis (MS) requires additional molecular markers. Recently, we used original TCA-precipitation/extraction approach in combination with MALDI TOF/TOF mass-spectrometry and identified earlier unknown 48 kDa form of the unconv
Autor:
Greg J. Duncan, Peggy Assinck, Michael Wegner, G. R. Wayne Moore, Ryan Hirata, Ben Emery, Sohrab B. Manesh, Fraser G. W. Muir, Jason R. Plemel, Jie Liu, Wolfram Tetzlaff, Matan Berson
Publikováno v:
Duncan, G J, Plemel, J R, Assinck, P, Manesh, S B, Muir, F G W, Hirata, R, Berson, M, Liu, J, Wegner, M, Emery, B, Moore, G R W & Tetzlaff, W 2017, ' Myelin regulatory factor drives remyelination in multiple sclerosis ', Acta Neuropathologica, vol. 134, no. 3, pp. 403-422 . https://doi.org/10.1007/s00401-017-1741-7
Remyelination is limited in the majority of multiple sclerosis (MS) lesions despite the presence of oligodendrocyte precursor cells (OPCs) in most lesions. This observation has led to the view that a failure of OPCs to fully differentiate underlies r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6e172c82fad569f762acf354e0de3a
https://hdl.handle.net/20.500.11820/9e58597c-2ff0-4ee6-958b-e7f240406b72
https://hdl.handle.net/20.500.11820/9e58597c-2ff0-4ee6-958b-e7f240406b72
Autor:
Guillaume Perriard, Mathieu Canales, Melanie Gentner, Lukas Enz, Myriam Schluep, Nicole Schaeren-Wiemers, Renaud Du Pasquier, Amandine Mathias
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, vol. 12, pp. 119
Journal of Neuroinflammation, vol. 12, pp. 119
Background Increasing evidences link T helper 17 (Th17) cells with multiple sclerosis (MS). In this context, interleukin-22 (IL-22), a Th17-linked cytokine, has been implicated in blood brain barrier breakdown and lymphocyte infiltration. Furthermore
Publikováno v:
European Journal of Neuroscience, 24(6), 1645-1652. Blackwell Publishing
Studies in experimental allergic encephalomyelitis, an animal model of multiple sclerosis (MS), suggest that astrocyte-secreted insulin-like growth factor binding protein-2 (IGFBP-2) helps target IGF-1 to IGF-1 receptor-expressing oligodendrocytes an
Autor:
Rocío Ramos-Medina, Bárbara Alonso, Armanda Casrouge, Janet Vega, Matthew L. Albert, Marta Tejera-Alhambra, Silvia Sánchez-Ramón, Clara de Andrés
Publikováno v:
Clinical Immunology
Clinical Immunology, Elsevier, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, Elsevier, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
International audience; Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. W
Autor:
Edda Thies, Aurélie Menigoz, Benjamin Schattling, Veit Flockerzi, Karin Steinbach, Olaf Pongs, Martin Kruse, Manuel A. Friese, Matthias Kneussel, Doron Merkler, Rudi Vennekens, Marc Freichel, Friederike Ufer, Wolfgang Brück
Publikováno v:
Nature Medicine, Vol. 18, No 12 (2012) pp. 1805-11
In multiple sclerosis, an inflammatory disease of the central nervous system (CNS), axonal and neuronal loss are major causes for irreversible neurological disability. However, which molecules contribute to axonal and neuronal injury under inflammato
Publikováno v:
Neuroscience Letters. 289:75-77
By using immunocytochemistry we previously reported the absence of beta(2) adrenergic receptors on astrocytes in multiple sclerosis (MS) white matter. Here, we measured beta(1) and beta(2) adrenergic receptor concentrations in postmortem brain sectio