Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Multifocal Glioblastomas"'
Autor:
Daniel M. Treisman, Wei Li, Bo Li, Benjamin A. Hoff, Alnawaz Rehemtulla, Siyuan Zheng, Brianna R. Pierce, Yinghua Li, Yuan Zhu, Yuan Wang, Seckin Akgul, Brian D. Ross, David O. Ferguson, Jun Li, Kevin A. Heist, Cheng-Ying Ho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications
Recent characterization of spatiotemporal genomic architecture of IDH-wild-type multifocal glioblastomas (M-GBMs) suggests a clinically unobserved common-ancestor (CA) with a less aggressive phenotype, generating highly genetically divergent malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1c99206120994c90914c519e533b50
https://doaj.org/article/4bdb60bfd8b842efb554542d31c8e854
https://doaj.org/article/4bdb60bfd8b842efb554542d31c8e854
Autor:
Sofia Asioli, Filippo Friso, Vittoria Rosetti, Giorgio Palandri, Vania Ramponi, Matteo Martinoni, Maria Pia Foschini, Paola Rucci, Arianna Rustici, Filippo Badaloni, Carmelo Lucio Sturiale, Carlo Bortolotti, Enrico Franceschi, Alessandro Carretta, Viscardo Paolo Fabbri, Matteo Zoli, Diego Mazzatenta, Alfredo Conti, Alba A. Brandes
BACKGROUND: Glioblastoma with multiple localizations (mGBMs) can be defined as multifocal, where enhancing lesions present a connection visible on magnetic resonance imaging fluid-attenuated inversion recovery imaging, or multicentric, in the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b52273a675622b77c768c6835aa6c01
http://hdl.handle.net/11585/849793
http://hdl.handle.net/11585/849793
Publikováno v:
SSRN Electronic Journal.
Background: Multifocal glioblastoma is an uncommon and refractory subtype of high grade glioma with poor prognosis. The epithelial-mesenchymal transition (EMT) is an important cause of enhanced glioblastoma invasiveness and tumor recurrence. Our prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac75d330e4f02fb588ae77d2170ff46
https://doi.org/10.2139/ssrn.3714633
https://doi.org/10.2139/ssrn.3714633
Autor:
Joseph R. Pecoraro, Robyn A. Wong, Stephen J. Forman, Christine E. Brown, Darya Alizadeh, Xin Yang
Publikováno v:
Neuro Oncol
Malignant gliomas (MG) are one of the deadliest cancers with very limited therapeutic options. Chimeric antigen receptor (CAR)-T cell therapy has emerged as a powerful strategy for B-cell malignancies and may offer new opportunities to improve outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721c628bd6e3e5a0cf136a3380cd1f1f
https://europepmc.org/articles/PMC6847902/
https://europepmc.org/articles/PMC6847902/
Autor:
J. A. Barcia, M.J. Rodríguez, David Molina-García, Julián Pérez-Beteta, Juan Martino, Víctor M. Pérez-García, David Albillo, Juan Manuel Sepúlveda, Á. Rodríguez De Lope, Antonio Revert, M. Villena, Ana Ramos, R. Morcillo, Pedro C. Lara, Estanislao Arana, Aurelio Hernández-Laín, Carlos Velasquez, Bárbara Meléndez-Asensio
Publikováno v:
American Journal of Neuroradiology.
BACKGROUND AND PURPOSE: Multifocal glioblastomas (ie, glioblastomas with multiple foci, unconnected in postcontrast pretreatment T1-weighted images) represent a challenge in clinical practice due to their poor prognosis. We wished to obtain imaging b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129024f2446da92886c90bfb3258dae0
https://doi.org/10.3174/ajnr.a6019
https://doi.org/10.3174/ajnr.a6019
Autor:
Joachim P. Steinbach, Stella Breuer, Patrick N. Harter, Michael C. Burger, Oliver Bähr, Hans Cieplik, Kea Franz
Publikováno v:
International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2469
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2469 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2469 (2017)
In patients with glioblastoma, antiangiogenic therapy with bevacizumab (BEV) has been shown to improve progression-free survival (PFS), but not overall survival (OS). Especially in patients with an unusual infiltrative phenotype as seen in multifocal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3616dd31a679a73a64588eea7424838
Autor:
Karl Hackmann, Barbara Klink, Beatriz Carvalho, Dietmar Krex, Matthias Lehmann, Michael Seifert, Evelin Schröck, Kerstin Becker, Achim Temme, Gabriele Schackert, Sophie Eisenreich, Andreas Rump, Khalil Abou-El-Ardat, Gerrit A. Meijer
Publikováno v:
Neuro-oncology. 19(4)
Background The evolution of primary glioblastoma (GBM) is poorly understood. Multifocal GBM (ie, multiple synchronous lesions in one patient) could elucidate GBM development. Methods We present the first comprehensive study of 12 GBM foci from 6 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d70c24bcc64e9ae71b85a79f6aff30
https://pubmed.ncbi.nlm.nih.gov/29868765
https://pubmed.ncbi.nlm.nih.gov/29868765
Autor:
Kristen Bradley, Bermans J. Iskandar, Kristen Casey, Mariah Bashir, Diane Puccetti, Tyce Kearl, M. Shariar Salamat, Neha Patel
INTRODUCTION: Multifocal glioblastoma is a rare entity in adults and children with an extremely poor prognosis. Multifocal GBM is thought to arise from the spread of the tumor via a connecting pathway. Because of this spread, complete resection is ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1757b3094450544355f1a3596b85e4b0
https://europepmc.org/articles/PMC4639224/
https://europepmc.org/articles/PMC4639224/
Publikováno v:
Neurosurgery. 48:940-944
Objective and importance We describe two cases of distant wounded glioma syndrome complicating surgical resection of multifocal glioblastoma multiforme. This clinical entity was previously described as a local phenomenon resulting in postoperative he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2f98e65f70f8dbe040f4da99840c2d
https://doi.org/10.1227/00006123-200104000-00053
https://doi.org/10.1227/00006123-200104000-00053
Publikováno v:
Neurosurgery. 53(6)
OBJECTIVE Multifocal glioblastomas constitute an increasingly diagnosed subgroup of glioblastoma multiforme, the most malignant primary brain tumor in adults. The molecular background of these lesions is unknown. However, the ability to study multipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7ede8cd04be808f0fe01f7b5436aa5
https://pubmed.ncbi.nlm.nih.gov/14633303
https://pubmed.ncbi.nlm.nih.gov/14633303