Zobrazeno 1 - 10
of 7 559
pro vyhledávání: '"Multicomponent Reaction"'
Autor:
Cesia M. Aguilar-Morales, América A. Frías-López, Nadia V. Emilio-Velázquez, Alejandro Islas-Jácome, Angelica Judith Granados-López, Jorge Gustavo Araujo-Huitrado, Yamilé López-Hernández, Hiram Hernández-López, Luis Chacón-García, Jesús Adrián López, Carlos J. Cortés-García
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 3077-3084 (2024)
A series of 1,5-disubstituted tetrazole-indole hybrids were synthesized via a high-order multicomponent reaction consisting of an Ugi-azide/Pd/Cu-catalyzed hetero-annulation cascade sequence. This operationally simple one-pot protocol allowed high bo
Externí odkaz:
https://doaj.org/article/005fa626141148e0962b0b132ff09bad
Autor:
Baptiste Leroux, Alexis Beaufils, Federico Banchini, Olivier Jackowski, Alejandro Perez-Luna, Fabrice Chemla, Marc Presset, Erwan Le Gall
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2834-2839 (2024)
The use of alkylzinc bromides in the multicomponent Mannich reaction is described. Heteroleptic organozinc compounds were obtained in THF or 2-MeTHF by direct insertion of zinc dust into the C–Br bond of alkyl bromides. It was found that the presen
Externí odkaz:
https://doaj.org/article/4b7b21f253ac485da4a8fbcb65eacfa9
Autor:
Jie Gao, Yonghua Zhai, Weihong Lu, Xianghe Jiang, Jingsheng Zhou, Lili Wu, Longhai Du, Chunqing Ou, Xinyi Zhang, Hanliang He, Jian Zhu, Zhengbiao Zhang, Meiyun Li, Yan Wu, Xiangqiang Pan
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 597-610 (2024)
In the field of cancer therapy, inhibiting autophagy has emerged as a promising strategy. However, pharmacological disruption of autophagy can lead to the upregulation of programmed death-ligand 1 (PD-L1), enabling tumor immune evasion. To address th
Externí odkaz:
https://doaj.org/article/0132123d6b9148a8a2f00a01aa7fa5b6
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2024-2077 (2024)
Pyrazoles are rarely found in nature but are traditionally used in the agrochemical and pharmaceutical industries, while other areas of use are also actively developing. However, they have also found numerous other applications. The search for new an
Externí odkaz:
https://doaj.org/article/c4c8dfdcb1e64ce09a7f54cae8329d37
Autor:
Kateryna V. Dil, Vitalii A. Palchykov
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2143-2151 (2024)
A one-pot three-component Biginelli synthesis of dihydropyrimidinones/thiones/selenones via acetic acid or solvent-free Yb(OTf)3-catalyzed tandem reaction of β-ketosulfone (dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide), an appropriate urea, and arylal
Externí odkaz:
https://doaj.org/article/8bba997055ed4d9e9dc7bb4818b34758
Autor:
Alexander V. Tsygankov, Vladyslav O. Vereshchak, Tetiana O. Savluk, Serhiy M. Desenko, Valeriia V. Ananieva, Oleksandr V. Buravov, Yana I. Sakhno, Svitlana V. Shishkina, Valentyn A. Chebanov
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1773-1784 (2024)
By one-pot four- and three-component Ugi reactions involving convertible isocyanides and unexplored pyrrole-containing β-chlorovinylaldehyde, a small library of 20 bisamides with unusual behavior in post-Ugi transformations was prepared and characte
Externí odkaz:
https://doaj.org/article/c87805b4505340978329371bae41d434
Autor:
Nuzhat Rehman, Ayaz Mahmood Dar, Raja Feroz Ahmad Haji, Sharief-ud-din Khan, Deepak Pareek, Saleem Farooq, Bashir Ahmad Dar
Publikováno v:
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, Vol 19, Iss 1, Pp 76-83 (2024)
This study introduces an environmentally sustainable approach for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs), via the Biginelli reaction. A heterogeneous catalyst, Heteropolyacid-Clay (HPA-Clay), is developed by immobilizing H5PV2W10O40
Externí odkaz:
https://doaj.org/article/bb7a639bfc2f4f6fa1bbec6a85d11f42
Autor:
Verma, Asha a, Kumar, Sandeep b, Khatri, Vineeta a, Pathak, Gargi a, Verma, Suresh Kumar c, Arya, Dinesh Kumar d, ⁎
Publikováno v:
In Journal of the Indian Chemical Society January 2025 102(1)
Autor:
Julio C. Flores-Reyes, Annia Galano, Sandra M. Rojas-Montoya, Luis Blancarte-Carrazco, Elba Xochitiotzi-Flores, Héctor García-Ortega, Norberto Farfán, Alejandro Islas-Jácome, Eduardo González-Zamora
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
A series of seven new meso-phenyl BODIPY-pyrrolo[3,4-b]pyridin-5-one conjugates were synthesized in one experimental step by using a Sc(III)-catalyzed Ugi-Zhu three-component reaction coupled to a cascade sequence (aza Diels-Alder/N-acylation/aromati
Externí odkaz:
https://doaj.org/article/c1637e0cde724991b378fa0e769f5517
Autor:
Naween M. Youns
Publikováno v:
Baghdad Science Journal, Vol 21, Iss 9 (2024)
A straightforward, one-pot, three-component reaction between substituted aromatic aldehydes, 2-naphthol and 4- aminoantipyrine have been used to synthesis a series of new 4-(((2-hydroxynaphthalen-1-yl) (phenyl) methylene) amino)-1,5-dimethyl-2-phenyl
Externí odkaz:
https://doaj.org/article/640dc9d27c8e445195a8f7b96ba70e0e