Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Multi-gene panel"'
Autor:
Emanuel Krebs, Deirdre Weymann, Cheryl Ho, Ian Bosdet, Janessa Laskin, Howard J. Lim, Stephen Yip, Aly Karsan, Timothy P. Hanna, Samantha Pollard, Dean A. Regier
Publikováno v:
The Lancet Regional Health. Americas, Vol 40, Iss , Pp 100936- (2024)
Summary: Background: Multi-gene panel sequencing streamlines treatment selection for advanced non-small cell lung cancer (NSCLC). Implementation continues to be uneven across jurisdictions, partly due to uncertain clinical and economic impacts. In Br
Externí odkaz:
https://doaj.org/article/111b1112bb8d497ea909af7e27f31682
Autor:
Krebs, Emanuel a, Weymann, Deirdre a, Ho, Cheryl b, c, Bosdet, Ian d, e, Laskin, Janessa b, c, Lim, Howard J. b, c, Yip, Stephen d, e, Karsan, Aly d, f, Hanna, Timothy P. g, h, Pollard, Samantha a, Regier, Dean A. a, i, ∗
Publikováno v:
In The Lancet Regional Health - Americas December 2024 40
Autor:
Teruhiko Yoshida, Yasushi Yatabe, Ken Kato, Genichiro Ishii, Akinobu Hamada, Hiroyuki Mano, Kuniko Sunami, Noboru Yamamoto, Takashi Kohno
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 1, Pp 29-44 (2024)
The journey to implement cancer genomic medicine (CGM) in oncology practice began in the 1980s, which is considered the dawn of genetic and genomic cancer research. At the time, a variety of activating oncogenic alterations and their functional signi
Externí odkaz:
https://doaj.org/article/098513c931e64fbb831a95e5cc3e139e
Autor:
Satoyo Oda, Mineko Ushiama, Wataru Nakamura, Masahiro Gotoh, Noriko Tanabe, Tomoko Watanabe, Yoko Odaka, Kazuhiko Aoyagi, Hiromi Sakamoto, Takeshi Nakajima, Kokichi Sugano, Teruhiko Yoshida, Yuichi Shiraishi, Makoto Hirata
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Genetic testing of the APC gene by sequencing analysis and MLPA is available across commercial laboratories for the definitive genetic diagnosis of familial adenomatous polyposis (FAP). However, some genetic alterations are difficult to detect using
Externí odkaz:
https://doaj.org/article/16a379c2dd3e48d5a80a14093eefaf68
Autor:
Federico Anaclerio, Lucrezia Pilenzi, Anastasia Dell’Elice, Rossella Ferrante, Simona Grossi, Luca Maria Ferlito, Camilla Marinelli, Simona Gildetti, Giuseppe Calabrese, Liborio Stuppia, Ivana Antonucci
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: A considerable number of families with pedigrees suggestive of a Mendelian form of Breast Cancer (BC), Ovarian Cancer (OC), or Pancreatic Cancer (PC) do not show detectable BRCA1/2 mutations after genetic testing. The use of multi-gene
Externí odkaz:
https://doaj.org/article/83e7c56e9d0a4a19bf5d770283c0d7ab
Akademický článek
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Akademický článek
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Autor:
Alicia Scocchia, Tiia Kangas-Kontio, Melita Irving, Matti Hero, Inka Saarinen, Liisa Pelttari, Kimberly Gall, Satu Valo, Johanna M. Huusko, Jonna Tallila, Johanna Sistonen, Juha Koskenvuo, Tero-Pekka Alastalo
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Skeletal dysplasia is typically diagnosed using a combination of radiographic imaging, clinical examinations, and molecular testing. Identifying a molecular diagnosis for an individual with a skeletal dysplasia can lead to improve
Externí odkaz:
https://doaj.org/article/1b5eb1816ae944fb88155d0665c41bec
Publikováno v:
GE: Portuguese Journal of Gastroenterology, Pp 1-7 (2021)
Genetic testing aims to identify patients at risk for inherited cancer susceptibility. In the last decade, there was a significant increase in the request of broader panels of genes as multi-gene panel testing became widely available. However, physic
Externí odkaz:
https://doaj.org/article/bd6f13bfa3b9479f9879d2639757894c
Autor:
Simone da Costa e Silva Carvalho, Nathalia Moreno Cury, Danielle Barbosa Brotto, Luiza Ferreira de Araujo, Reginaldo Cruz Alves Rosa, Lorena Alves Texeira, Jessica Rodrigues Plaça, Adriana Aparecida Marques, Kamila Chagas Peronni, Patricia de Cássia Ruy, Greice Andreotti Molfetta, Julio Cesar Moriguti, Dirce Maria Carraro, Edenir Inêz Palmero, Patricia Ashton-Prolla, Victor Evangelista de Faria Ferraz, Wilson Araujo Silva Jr
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-24 (2020)
Abstract Background The Hereditary Breast and Ovarian Cancer Syndrome (HBOC) occurs in families with a history of breast/ovarian cancer, presenting an autosomal dominant inheritance pattern. BRCA1 and BRCA2 are high penetrance genes associated with a
Externí odkaz:
https://doaj.org/article/7017c847d5db4a25b8ac154488e75410