Zobrazeno 1 - 10
of 921
pro vyhledávání: '"Multi-arm"'
Autor:
Jonathan Beall, Jordan Elm, Matthew W. Semler, Li Wang, Todd Rice, Hooman Kamel, William Mack, Akshitkumar M. Mistry
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background Multi-Arm, Multi-Stage (MAMS) clinical trial designs allow for multiple therapies to be compared across a spectrum of clinical trial phases. MAMS designs fall under several overarching design groups, including adaptive designs (AD
Externí odkaz:
https://doaj.org/article/28db3457ec2c49f5b8a9d42f1c6f8021
Autor:
Melissa Pyle, Lucy Loftus, Richard Emsley, Daniel Freeman, Steven Gillard, Andrew Gumley, Justyna Sierpatowska, Lisa Wood, Rory C. O’Connor, Paul Pfeiffer, Sharon Anne Simpson, Nicole Cockayne, Gemma Shields, Ariane Beckley, Helen Beckwith, Maria Filippidou, Callum Glen, Stephanie Allan, Raj Hazzard, Eleanor Longden, Heather Peel, Mark Larsen, Sandra Bucci, Anthony P. Morrison
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background People with serious mental health problems (SMHP) are more likely to be admitted to psychiatric hospital following contact with crisis services. Admissions can have significant personal costs, be traumatic and are the most expensi
Externí odkaz:
https://doaj.org/article/d8f8a6b657044f61bf7c2cdd511ad029
Autor:
Babak Choodari-Oskooei, Alexandra Blenkinsop, Kelly Handley, Thomas Pinkney, Mahesh K. B. Parmar
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Multi-arm multi-stage (MAMS) randomised trial designs have been proposed to evaluate multiple research questions in the confirmatory setting. In designs with several interventions, such as the 8-arm 3-stage ROSSINI-2 trial for pre
Externí odkaz:
https://doaj.org/article/f169275c95354f73bdb833b5346d695c
Autor:
Yue Zhang, Dongtian Miao, Mingli Su, Yinxiang Tang, Minghong Zhou, Yang Yu, Xuefeng Guo, Dingcai Wu
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Easy injection, long‐lasting barrier, and drug loading are the critical properties of submucosal injection materials for endoscopic surgery. However, conventional injectable polymers face challenges in simultaneously attaining these proper
Externí odkaz:
https://doaj.org/article/21b3ef1b84ea4d1ca1fa63ae3f43e90c
Autor:
Hisham Mehanna, Piers Gaunt, Anthony Kong, Andrew Hartley, Paul Sanghera, Martin Forster, Mehmet Sen, Vinidh Paleri, Charles Fong, Dinos Geropantas, Devraj Srinivasan, Satya Garikipati, Rafael Moleron, Georgina Casswell, Eleanor Aynsley, Amy Ward, Lorcan O’Toole, Arafat Mirza, Charlotte Firth, Isla Humphreys, Tessa Fulton-Lieuw, Tom Roques, Paul Nankivell
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Patients with intermediate and high-risk oropharyngeal cancer (OPC) have poorer response to standard treatment and poorer overall survival compared to low-risk OPC. CompARE is designed to test alternative approaches to intensified
Externí odkaz:
https://doaj.org/article/330dec8870f14404b747cb77cc116ff3
Publikováno v:
Digital Communications and Networks, Vol 9, Iss 5, Pp 1200-1211 (2023)
In order to solve the high latency of traditional cloud computing and the processing capacity limitation of Internet of Things (IoT) users, Multi-access Edge Computing (MEC) migrates computing and storage capabilities from the remote data center to t
Externí odkaz:
https://doaj.org/article/acac3c0b27184790b251a72dbbd7b1a8
Autor:
Richard A. Parker, Christopher J. Weir, Tra My Pham, Ian R. White, Nigel Stallard, Mahesh K. B. Parmar, Robert J. Swingler, Rachel S. Dakin, Suvankar Pal, Siddharthan Chandran
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background MND-SMART is a platform, multi-arm, multi-stage, multi-centre, randomised controlled trial recruiting people with motor neuron disease. Initially, the treatments memantine and trazodone will each be compared against placebo, but o
Externí odkaz:
https://doaj.org/article/79ee44339d2044749471abb674bbc6f1
Autor:
Sharon B. Love, Fay Cafferty, Claire Snowdon, Karen Carty, Joshua Savage, Philip Pallmann, Lucy McParland, Louise Brown, Lindsey Masters, Francesca Schiavone, Dominic Hague, Stephen Townsend, Claire Amos, Annabelle South, Kate Sturgeon, Ruth Langley, Timothy Maughan, Nicholas James, Emma Hall, Sarah Kernaghan, Judith Bliss, Nick Turner, Andrew Tutt, Christina Yap, Charlotte Firth, Anthony Kong, Hisham Mehanna, Colin Watts, Robert Hills, Ian Thomas, Mhairi Copland, Sue Bell, David Sebag-Montefiore, Robert Jones, Mahesh K. B. Parmar, Matthew R. Sydes
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Late-phase platform protocols (including basket, umbrella, multi-arm multi-stage (MAMS), and master protocols) are generally agreed to be more efficient than traditional two-arm clinical trial designs but are not extensively used.
Externí odkaz:
https://doaj.org/article/f16f51eff76c45b9b2545597e35df8a3
Publikováno v:
Drones, Vol 7, Iss 11, p 656 (2023)
With multi-sensors embedded, flexible unmanned aerial vehicles (UAVs) can collect sensory data and provide various services for all walks of life. However, limited computing capability and battery energy put a great burden on UAVs to handle emerging
Externí odkaz:
https://doaj.org/article/fe3bccc2b75045898c87163b7d512acf
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