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Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes

Autor: Multhaup, Michael L., Seldin, Marcus M., Jaffe, Andrew E., Lei, Xia, Kirchner, Henriette, Mondal, Prosenjit, Li, Yuanyuan, Rodriguez, Varenka, Drong, Alexander, Hussain, Mehboob, Lindgren, Cecilia, McCarthy, Mark, Näslund, Erik, Zierath, Juleen R., Wong, G. William, Feinberg, Andrew P.

Publikováno v: In Cell Metabolism 6 January 2015 21(1):138-149

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DNA methylation age of blood predicts all-cause mortality in later life

Autor: Marioni, Riccardo E, Shah, Sonia, McRae, Allan F, Chen, Brian H, Colicino, Elena, Harris, Sarah E, Gibson, Jude, Henders, Anjali K, Redmond, Paul, Cox, Simon R, Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G, Montgomery, Grant W, Feinberg, Andrew P, Fallin, M, Multhaup, Michael L, Jaffe, Andrew E, Joehanes, Roby, Schwartz, Joel, Just, Allan C, Lunetta, Kathryn L, Murabito, Joanne M, Starr, John M, Horvath, Steve, Baccarelli, Andrea A, Levy, Daniel, Visscher, Peter M, Wray, Naomi R, Deary, Ian J

Publikováno v: Marioni, R E, Shah, S, McRae, A F, Chen, B H, Colicino, E, Harris, S E, Gibson, J, Henders, A K, Redmond, P, Cox, S R, Pattie, A, Corley, J, Murphy, L, Martin, N G, Montgomery, G W, Feinberg, A P, Fallin, M D, Multhaup, M L, Jaffe, A E, Joehanes, R, Schwartz, J, Just, A C, Lunetta, K L, Murabito, J M, Starr, J M, Horvath, S, Baccarelli, A A, Levy, D, Visscher, P M, Wray, N R & Deary, I J 2015, ' DNA methylation age of blood predicts all-cause mortality in later life ', Genome Biology, vol. 16, 25 . https://doi.org/10.1186/s13059-015-0584-6
Genome biology, vol 16, iss 1
Genome Biology

Background DNA methylation levels change with age. Recent studies have identified biomarkers of chronological age based on DNA methylation levels. It is not yet known whether DNA methylation age captures aspects of biological age. Results Here we tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::336fc32c8d12424be4b0441661831918
https://hdl.handle.net/20.500.11820/353bbf69-e386-4788-805d-9cb18b41baeb

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.

Autor: Mendelson, Michael M., Marioni, Riccardo E., Joehanes, Roby, Liu, Chunyu, Hedman, Åsa K., Aslibekyan, Stella, Demerath, Ellen W., Guan, Weihua, Zhi, Degui, Yao, Chen, Huan, Tianxiao, Willinger, Christine, Chen, Brian, Courchesne, Paul, Multhaup, Michael, Irvin, Marguerite R., Cohain, Ariella, Schadt, Eric E., Grove, Megan L., Bressler, Jan

Publikováno v: PLoS Medicine; 1/17/2017, Vol. 14 Issue 1, p1-30, 30p, 2 Diagrams, 5 Charts, 1 Graph