Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron.

Autor: Benlarbi M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Laroche G; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Fink C; Department of Microbiology & Immunology, Schulich School of Medicine & Dentistry Western University, London, ON N6A 5C1, Canada.; Molecular Medicine Research Laboratories, Robarts Research Institute, University of Western Ontario, London, ON N6A 5C1, Canada., Fu K; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Mulloy RP; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Phan A; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Ariana A; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Stewart CM; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Prévost J; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3C 3J7, Canada., Beaudoin-Bussières G; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3C 3J7, Canada., Daniel R; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Bo Y; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., El Ferri O; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Yockell-Lelièvre J; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; The Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Stanford WL; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; The Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Giguère PM; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Mubareka S; Sunnybrook Research Institute, Toronto, ON M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada., Finzi A; Centre de Recherche du CHUM, Montréal, QC H2X 0A9, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, QC H3C 3J7, Canada., Dekaban GA; Department of Microbiology & Immunology, Schulich School of Medicine & Dentistry Western University, London, ON N6A 5C1, Canada.; Molecular Medicine Research Laboratories, Robarts Research Institute, University of Western Ontario, London, ON N6A 5C1, Canada., Dikeakos JD; Department of Microbiology & Immunology, Schulich School of Medicine & Dentistry Western University, London, ON N6A 5C1, Canada.; Molecular Medicine Research Laboratories, Robarts Research Institute, University of Western Ontario, London, ON N6A 5C1, Canada., Côté M; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 8M5, Canada.; Centre for Infection, Immunity and Inflammation, University of Ottawa, Ottawa, ON K1H 8M5, Canada.

Publikováno v: IScience [iScience] 2022 Nov 18; Vol. 25 (11), pp. 105316. Date of Electronic Publication: 2022 Oct 10.

Human coronaviruses disassemble processing bodies.

Autor: Kleer M; Microbiology, Immunology and Infectious Diseases Department, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Research Institute, University of Calgary, Calgary, Alberta, Canada.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada., Mulloy RP; Microbiology, Immunology and Infectious Diseases Department, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Research Institute, University of Calgary, Calgary, Alberta, Canada.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada., Robinson CA; Microbiology, Immunology and Infectious Diseases Department, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Research Institute, University of Calgary, Calgary, Alberta, Canada.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada., Evseev D; Microbiology, Immunology and Infectious Diseases Department, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Research Institute, University of Calgary, Calgary, Alberta, Canada.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada., Bui-Marinos MP; Microbiology, Immunology and Infectious Diseases Department, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Research Institute, University of Calgary, Calgary, Alberta, Canada.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada., Castle EL; School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada., Banerjee A; Vaccine and Infectious Disease Organization, University of Saskatchewan; Saskatoon, Saskatchewan, Canada.; Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan; Saskatoon, Saskatchewan, Canada.; Department of Biology, University of Waterloo; Waterloo, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Mubareka S; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Research Institute, Toronto, Ontario, Canada., Mossman K; Department of Medicine, Master University, Hamilton, Ontario, Canada.; Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada., Corcoran JA; Microbiology, Immunology and Infectious Diseases Department, University of Calgary, Calgary, Alberta, Canada.; Charbonneau Cancer Research Institute, University of Calgary, Calgary, Alberta, Canada.; Snyder Institute for Chronic Diseases, University of Calgary, Calgary, Alberta, Canada.

Publikováno v: PLoS pathogens [PLoS Pathog] 2022 Aug 23; Vol. 18 (8), pp. e1010724. Date of Electronic Publication: 2022 Aug 23 (Print Publication: 2022).