Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mullican, Michael D."'
Autor:
Stuart Donald Jones, Murdoch Robert, Mullican Michael D, Golec Julian M C, Yu-Ping Luong, David J. Livingston, Scott A. Raybuck, Guy W. Bemis, Murcko Mark A, David Kay, Wilson Keith P
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2181-2186
Pyridone derivatives, especially with 6-aryl substituents, have been shown to be useful P2-P3 peptidomimetic scaffolds for the design of potent inhibitors of ICE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::414dc5a161182b8e487d4a6ff846f727
https://doi.org/10.1016/s0960-894x(97)00394-6
https://doi.org/10.1016/s0960-894x(97)00394-6
Autor:
Phillip L. Evans, Saroop S. Matharu, Scott A. Raybuck, David Kay, Yu-Ping Luong, Lauffer David J, Murcko Mark A, David J. Livingston, Mullican Michael D, Golec Julian M C, Roger John Gillespie, Geoffrey M. Porritt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:2359-2364
The tetrapeptide aldehyde Ac-Tyr-Val-Ala-AspH ( 1 , L-709,049) has been reported to be a potent reversible inhibitor of Interleukin-1β Converting Enzyme (ICE). We have prepared a series of analogs of 1 , in order to explore the active sige of ICE. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab93ad698808a5cf3b6d4bee3e5c5c3d
https://doi.org/10.1016/0960-894x(94)85040-2
https://doi.org/10.1016/0960-894x(94)85040-2
Autor:
Lauffer David J, Mullican Michael D
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:1225-1227
A simple and versatile method for the synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2,3,4,5-tetrahydro-1,5-benzodiazepine-1-acetic acid methyl ester (4), a dipeptide mimetic, has been developed. The regioselective functionalization of the N1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fa29b58c7de4bfe9df5681543765c8
https://doi.org/10.1016/s0960-894x(02)00107-5
https://doi.org/10.1016/s0960-894x(02)00107-5
Autor:
Lauffer David J, Mullican Michael D
Publikováno v:
ChemInform. 33
A simple and versatile method for the synthesis of (S) 3-tert-butoxycarbonylamino-2-oxo-2,3,4,5-tetrahydro-1,5-benzodiazepine-1-acetic acid methyl ester (4), a dipeptide mimetic, has been developed. The regioselective functionalization of the N1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a23cf62dd6acb5bd86e0c1f3ec4c4ac9
https://doi.org/10.1002/chin.200233179
https://doi.org/10.1002/chin.200233179
Autor:
Mullican Michael D, Mashall Robert, Wilson Keith P, Michael S. Su, Murcko Mark A, Paul R. Caron
Publikováno v:
Current opinion in chemical biology. 5(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e385310c2c4acbe801257f129b23fb50
https://pubmed.ncbi.nlm.nih.gov/11470611
https://pubmed.ncbi.nlm.nih.gov/11470611
Autor:
Caron, Paul R, Mullican, Michael D, Mashal, Robert D, Wilson, Keith P, Su, Michael S, Murcko, Mark A
Publikováno v:
In Current Opinion in Chemical Biology 2001 5(4):464-470
Akademický článek
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Publikováno v:
ChemInform; Aug2002, Vol. 33 Issue 33, pno-no, 1p
Autor:
Mullican, Michael D., Lauffer, David J., Gillespie, Roger J., Matharu, Saroop S., Kay, David, Porritt, Geoffrey M., Evans, Phillip L., Golec, Julian M.C., Murcko, Mark A., Luong, Yu-Ping, Raybuck, Scott A., Livingston, David J.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1994 4(19):2359-2364
Autor:
Golec, Julian M.C., Mullican, Michael D., Murcko, Mark A., Wilson, Keith P., Kay, David P., Jones, Stuart D., Murdoch, Robert, Bemis, Guy W., Raybuck, Scott A., Luong, Yu-Ping, Livingston, David J.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1997 7(17):2181-2186