Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mullet SJ"'
Persistent DNA damage rewires lipid metabolism and promotes histone hyperacetylation via MYS-1/Tip60
Autor:
Hannah L. Pepper, Shruthi Hamsanathan, Stacy G. Wendell, Aditi U. Gurkar, Mullet Sj, Payel Sen, SeungHye Han, Tamil S. Anthonymuthu, Nathaniel W. Snyder, Sims Aa, Valerian E. Kagan, Hülya Bayır, Shinglot H, Siefken E
Nuclear DNA damage is intricately linked to cellular metabolism. However, the underlying mechanisms and full range of metabolic alterations that occur in response to persistent DNA damage are not well understood. Here, we use a DNA repair-deficient m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61002edcdf6e59ebcc48eea1c17d3513
https://doi.org/10.1101/2021.06.24.449832
https://doi.org/10.1101/2021.06.24.449832
Autor:
Xie B; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Ramirez W; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Mills AM; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Huckestein BR; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Anderson M; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Pangburn MM; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Lang EY; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Mullet SJ; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA, USA., Chuan BW; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Guo L; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Sipula I; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., O'Donnell CP; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Wendell SG; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA.; Health Sciences Metabolomics and Lipidomics Core, University of Pittsburgh, Pittsburgh, PA, USA., Scott I; Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Metabolism and Mitochondrial Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Jurczak MJ; Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Center for Metabolism and Mitochondrial Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Publikováno v:
Current research in physiology [Curr Res Physiol] 2022 May 28; Vol. 5, pp. 232-239. Date of Electronic Publication: 2022 May 28 (Print Publication: 2022).
Autor:
Li DD; Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Jawale CV; Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Zhou C; Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Lin L; Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Trevejo-Nunez GJ; Division of Infectious Diseases, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Rahman SA; Center for Systems Immunology, Departments of Immunology and Computational & Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA., Mullet SJ; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Das J; Center for Systems Immunology, Departments of Immunology and Computational & Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA., Wendell SG; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA., Delgoffe GM; Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA., Lionakis MS; Fungal Pathogenesis Section, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Gaffen SL; Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Biswas PS; Division of Rheumatology & Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: psb13@pitt.edu.
Publikováno v:
Cell host & microbe [Cell Host Microbe] 2022 Apr 13; Vol. 30 (4), pp. 530-544.e6. Date of Electronic Publication: 2022 Mar 21.
Autor:
Li T; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Kidney Transplantation and., Zhang Z; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Organ Transplantation and General Surgery, Second Xiangya Hospital of Central South University, Changsha, China., Bartolacci JG; Department of Surgery and.; McGowan Institute for Regenerative Medicine and., Dwyer GK; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Liu Q; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Southern University of Science and Technology, Shenzhen, China., Mathews LR; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Velayutham M; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Pittsburgh Heart, Lung, and Blood, Vascular Medicine Institute and.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Roessing AS; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Lee YC; McGowan Institute for Regenerative Medicine and.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Dai H; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Kidney Transplantation and., Shiva S; Pittsburgh Heart, Lung, and Blood, Vascular Medicine Institute and.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Oberbarnscheidt MH; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Dziki JL; Department of Surgery and.; McGowan Institute for Regenerative Medicine and., Mullet SJ; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Health Sciences Metabolomics and Lipidomics Core and.; Clinical Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Wendell SG; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Health Sciences Metabolomics and Lipidomics Core and.; Clinical Translational Science Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Wilkinson JD; Department of Pediatrics, Vanderbilt School of Medicine, Nashville, Tennessee, USA., Webber SA; Department of Pediatrics, Vanderbilt School of Medicine, Nashville, Tennessee, USA., Wood-Trageser M; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Pathology and., Watkins SC; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Demetris AJ; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; McGowan Institute for Regenerative Medicine and.; Department of Pathology and., Hussey GS; Department of Surgery and.; McGowan Institute for Regenerative Medicine and., Badylak SF; Department of Surgery and.; McGowan Institute for Regenerative Medicine and.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Turnquist HR; Department of Surgery and.; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; McGowan Institute for Regenerative Medicine and.; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Publikováno v:
The Journal of clinical investigation [J Clin Invest] 2020 Oct 01; Vol. 130 (10), pp. 5397-5412.