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Afriplex GRTTM extract attenuates hepatic steatosis in an in vitro model of NAFLD.

Autor: Gabuza K; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa.; Department of Biotechnology, University of the Western Cape, Bellville, Cape Town, South Africa., Mabuda TI; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa.; Department of Biotechnology, University of the Western Cape, Bellville, Cape Town, South Africa., Patel O; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa., Khuboni N; Department of Biochemistry and Microbiology, University of Zululand, eMpangeni, South Africa., van Aarde R; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa., Riedel S; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa.; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, South Africa., Sangweni NF; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa., Windvogel S; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, South Africa., Johnson R; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa.; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, South Africa., Muller CJF; Biomedical Research and Innovation Platform, South African Medical Research Council, Parow Valley, Cape Town, South Africa.; Department of Biochemistry and Microbiology, University of Zululand, eMpangeni, South Africa.; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town, South Africa.

Publikováno v: PloS one [PLoS One] 2024 Apr 17; Vol. 19 (4), pp. e0297572. Date of Electronic Publication: 2024 Apr 17 (Print Publication: 2024).

Pancreatic beta cell regenerative potential of Zanthoxylum chalybeum Engl. Aqueous stem bark extract.

Autor: Kimani CN; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg, 7505, South Africa; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa; Department of Non-communicable Diseases, Institute of Primate Research, PO Box 24481, Karen, Nairobi, Kenya. Electronic address: njokikimani@primateresearch.org., Reuter H; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa., Kotzé SH; Division of Clinical Anatomy, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa; Division of Anatomy, Department of Biomedical Sciences, School of Veterinary Medicine, Ross University, PO Box 334, Basseterre, Saint Kitts and Nevis., Venter P; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg, 7505, South Africa., Ramharack P; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg, 7505, South Africa; Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa., Muller CJF; Biomedical Research and Innovation Platform (BRIP), South African Medical Research Council (SAMRC), Tygerberg, 7505, South Africa; Centre for Cardio-Metabolic Research in Africa, Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, 7600, South Africa; Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, 3886, South Africa.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Feb 10; Vol. 320, pp. 117374. Date of Electronic Publication: 2023 Nov 07.

A high fat, high sugar diet induces hepatic Peroxisome proliferator-activated receptor gamma coactivator 1-alpha promoter hypermethylation in male Wistar rats.

Autor: Abrahams Y; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Willmer T; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa; Division of Cell Biology, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Patel O; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa; Division of Clinical Pharmacology, Department of Medicine, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa., Samodien E; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa., Muller CJF; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa; Department of Biochemistry and Microbiology, University of Zululand, Kwadlangezwa, South Africa., Windvogel S; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Johnson R; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Pheiffer C; Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg, South Africa; Centre for Cardio-Metabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa; Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa. Electronic address: carmen.pheiffer@mrc.ac.za.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Nov 05; Vol. 680, pp. 25-33. Date of Electronic Publication: 2023 Sep 07.