Broad-spectrum kinome profiling identifies CDK6 upregulation as a driver of lenvatinib resistance in hepatocellular carcinoma.

Autor: Leung CON; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Yang Y; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Leung RWH; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., So KKH; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China., Guo HJ; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Lei MML; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Muliawan GK; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China., Gao Y; State Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, Fourth Military Medical University, Xi'An, China., Yu QQ; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Yun JP; Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China., Ma S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Zhao Q; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China. q.zhao@polyu.edu.hk.; Research Institute for Future Food, The Hong Kong Polytechnic University, Hong Kong, China. q.zhao@polyu.edu.hk.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, China. q.zhao@polyu.edu.hk., Lee TKW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China. terence.kw.lee@polyu.edu.hk.; Research Institute for Future Food, The Hong Kong Polytechnic University, Hong Kong, China. terence.kw.lee@polyu.edu.hk.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, China. terence.kw.lee@polyu.edu.hk.

Publikováno v: Nature communications [Nat Commun] 2023 Oct 23; Vol. 14 (1), pp. 6699. Date of Electronic Publication: 2023 Oct 23.

Interplay between Wnt signaling molecules and exosomal miRNAs in breast cancer (Review).

Autor: Li, Hailong, Li, Xia, Du, Wei

Publikováno v: Oncology Reports; Aug2024, Vol. 52 Issue 2, pN.PAG-N.PAG, 1p