Modulation of intestinal epithelial permeability by chronic small intestinal helminth infections.

Autor: Mules TC; Malaghan Institute of Medical Research, Wellington, New Zealand.; University of Otago, Wellington, New Zealand., Tang JS; Malaghan Institute of Medical Research, Wellington, New Zealand.; High-Value Nutrition National Science Challenge, Auckland, New Zealand., Vacca F; Malaghan Institute of Medical Research, Wellington, New Zealand., Yumnam B; Malaghan Institute of Medical Research, Wellington, New Zealand., Schmidt A; Malaghan Institute of Medical Research, Wellington, New Zealand., Lavender B; Malaghan Institute of Medical Research, Wellington, New Zealand., Maclean K; Malaghan Institute of Medical Research, Wellington, New Zealand., Noble SL; Malaghan Institute of Medical Research, Wellington, New Zealand., Waugh C; Cawthron Institute, Nelson, New Zealand., van Ginkel R; Cawthron Institute, Nelson, New Zealand., Camberis M; Malaghan Institute of Medical Research, Wellington, New Zealand., Le Gros G; Malaghan Institute of Medical Research, Wellington, New Zealand., Inns S; Malaghan Institute of Medical Research, Wellington, New Zealand.; University of Otago, Wellington, New Zealand.

Publikováno v: Immunology and cell biology [Immunol Cell Biol] 2024 May-Jun; Vol. 102 (5), pp. 396-406. Date of Electronic Publication: 2024 Apr 22.

The Disease Severity Index for Inflammatory Bowel Disease Is a Valid Instrument that Predicts Complicated Disease.

Autor: Swaminathan A; Department of Medicine, University of Otago, Christchurch, New Zealand.; Department of Gastroenterology, Christchurch Hospital, New Zealand., Fulforth JM; Department of Gastroenterology, Waikato Hospital, Hamilton, New Zealand., Frampton CM; Department of Medicine, University of Otago, Christchurch, New Zealand., Borichevsky GM; Department of Medicine, University of Otago, Christchurch, New Zealand., Mules TC; Department of Medicine, University of Otago, Christchurch, New Zealand.; Department of Gastroenterology, Christchurch Hospital, New Zealand., Kilpatrick K; Department of Gastroenterology, Christchurch Hospital, New Zealand., Choukour M; Centre Hospitalier Régional Universitaire (CHRU) Nancy, Délégation à la Recherche Clinique et à l'Innovation, Plateforme Maladies Inflammatoires Chroniques de l'Intestin (MICI), Vandoeuvre-lès-Nancy, France., Fields P; Division of Gastroenterology and Hepatology, School of Medicine & Dentistry, University of Rochester, Rochester, NY, USA., Ramkissoon R; Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Helms E; Department of Gastroenterology, Concord Hospital, Sydney, Australia., Hanauer SB; Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Leong RW; Department of Gastroenterology, Concord Hospital, Sydney, Australia., Peyrin-Biroulet L; Deartment of Gastroenterology, Nancy University Hospital, F-54500 Vandoeuvre-les-Nancy, France.; INSERM, NGERE, University of Lorraine, F-54000 Nancy, France.; INFINY Institute, Nancy University Hospital, F-54500 Vandoeuvre-les-Nancy, France.; FHU-CURE, Nancy University Hospital, F-54500 Vandoeuvre-les-Nancy, France.; Groupe Hospitalier privé Ambroise Paré-Hartmann, Paris IBD Center, 92200 Neuilly sur Seine, France.; Division of Gastroenterology and Hepatology, McGill University Health Centre, Montreal, Quebec, Canada., Siegel CA; Section of Gastroenterology and Hepatology, Dartmouth Hitchcock Medical Center, LebanonNew Hampshire, USA., Gearry RB; Department of Medicine, University of Otago, Christchurch, New Zealand.; Department of Gastroenterology, Christchurch Hospital, New Zealand.

Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2024 Nov 04; Vol. 30 (11), pp. 2064-2075.

Controlled Hookworm Infection for Medication-free Maintenance in Patients with Ulcerative Colitis: A Pilot, Double-blind, Randomized Control Trial.

Autor: Mules TC; Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, Otago University, Wellington, New Zealand., Lavender B; Malaghan Institute of Medical Research, Wellington, New Zealand., Maclean K; Malaghan Institute of Medical Research, Wellington, New Zealand., Vacca F; Malaghan Institute of Medical Research, Wellington, New Zealand., Noble SL; Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, Otago University, Wellington, New Zealand., Yumnam B; Malaghan Institute of Medical Research, Wellington, New Zealand., Te Kawa T; Malaghan Institute of Medical Research, Wellington, New Zealand., Cait A; Malaghan Institute of Medical Research, Wellington, New Zealand., Tang J; Malaghan Institute of Medical Research, Wellington, New Zealand., O'Sullivan D; Malaghan Institute of Medical Research, Wellington, New Zealand., Gasser O; Malaghan Institute of Medical Research, Wellington, New Zealand., Stanley J; Biostatistics Group, Otago University, Wellington, New Zealand., Le Gros G; Malaghan Institute of Medical Research, Wellington, New Zealand., Camberis M; Malaghan Institute of Medical Research, Wellington, New Zealand., Inns S; Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, Otago University, Wellington, New Zealand.

Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2024 May 02; Vol. 30 (5), pp. 735-745.

Controlled infection with cryopreserved human hookworm induces CTLA-4 expression on Tregs and upregulates tryptophan metabolism.

Autor: Vacca F; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Mules TC; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, University of Otago, Wellington, New Zealand.; Gastroenterology, Te Whatu Ora, Capital Coast and Hutt Valley, Wellington, New Zealand., Camberis M; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Lavender B; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Noble SL; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand.; Department of Medicine, University of Otago, Wellington, New Zealand., Cait A; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Maclean K; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Mamum J; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Yumnam B; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Te Kawa T; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Ferrer-Font L; Hugh Green Technology Centre, Malaghan Institute of Medical Research, Wellington, New Zealand., Tang JS; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Gasser O; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Le Gros G; Le Gros Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand., Inns S; Department of Medicine, University of Otago, Wellington, New Zealand.; Gastroenterology, Te Whatu Ora, Capital Coast and Hutt Valley, Wellington, New Zealand.

Publikováno v: Gut microbes [Gut Microbes] 2024 Jan-Dec; Vol. 16 (1), pp. 2416517. Date of Electronic Publication: 2024 Oct 16.

The Impact of Disease Activity on Sexual and Erectile Dysfunction in Patients With Inflammatory Bowel Disease.

Autor: Mules TC; Department of Gastroenterology, Christchurch Hospital, Canterbury District Health Board, Canterbury, New Zealand., Swaminathan A; Department of Gastroenterology, Christchurch Hospital, Canterbury District Health Board, Canterbury, New Zealand.; Department of Medicine, University of Otago, Christchurch, Canterbury, New Zealand., Hirschfeld E; Department of Medicine, University of Otago, Christchurch, Canterbury, New Zealand., Borichevsky GM; Centre for Free Radical Research, University of Otago, Christchurch, Canterbury, New Zealand., Frampton CM; Department of Medicine, University of Otago, Christchurch, Canterbury, New Zealand., Day AS; Department of Paediatrics, University of Otago, Christchurch, Canterbury, New Zealand., Gearry RB; Department of Gastroenterology, Christchurch Hospital, Canterbury District Health Board, Canterbury, New Zealand.; Department of Medicine, University of Otago, Christchurch, Canterbury, New Zealand.

Publikováno v: Inflammatory bowel diseases [Inflamm Bowel Dis] 2023 Aug 01; Vol. 29 (8), pp. 1244-1254.