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Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias.

Autor: Selvakumar D; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia.; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Clayton ZE; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Prowse A; Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, St Lucia, Queensland, Australia., Dingwall S; Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, St Lucia, Queensland, Australia., Kim SK; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia.; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Reyes L; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., George J; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Shah H; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Chen S; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Leung HHL; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Hume RD; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Tjahjadi L; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Igoor S; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Skelton RJP; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Hing A; Department of Cardiothoracic Surgery, Westmead Hospital, Westmead, New South Wales, Australia., Paterson H; Sydney Imaging, Core Research Facility, the University of Sydney, Sydney, New South Wales, Australia., Foster SL; Department of Radiology, Westmead Hospital, Westmead, New South Wales, Australia.; Sydney School of Health Sciences, Faculty of Medicine and Health, the University of Sydney, Sydney, New South Wales, Australia., Pearson L; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Wilkie E; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Marcus AD; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia., Jeyaprakash P; Department of Cardiology, Nepean Hospital, Kingswood, New South Wales, Australia., Wu Z; Institute for Molecular Bioscience, the University of Queensland, St Lucia, Queensland, Australia., Chiu HS; Institute for Molecular Bioscience, the University of Queensland, St Lucia, Queensland, Australia., Ongtengco CFJ; Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, St Lucia, Queensland, Australia., Mulay O; Genomics and Machine Learning Lab, Division of Genetics and Genomics, Institute for Molecular Bioscience, the University of Queensland, St Lucia, Queensland, Australia., McArthur JR; Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.; St. Vincent's Clinical School, UNSW, Darlinghurst, New South Wales, Australia., Barry T; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Lu J; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Tran V; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Bennett R; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Kotake Y; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Campbell T; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Turnbull S; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Gupta A; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Nguyen Q; Genomics and Machine Learning Lab, Division of Genetics and Genomics, Institute for Molecular Bioscience, the University of Queensland, St Lucia, Queensland, Australia., Ni G; Genomics and Machine Learning Lab, Division of Genetics and Genomics, Institute for Molecular Bioscience, the University of Queensland, St Lucia, Queensland, Australia., Grieve SM; Imaging and Phenotyping Laboratory, Faculty of Medicine and Health, Charles Perkins Centre, the University of Sydney, Sydney, New South Wales, Australia., Palpant NJ; Institute for Molecular Bioscience, the University of Queensland, St Lucia, Queensland, Australia., Pathan F; Department of Cardiology, Nepean Hospital, Kingswood, New South Wales, Australia.; Sydney Medical School, Charles Perkins Centre Nepean, Faculty of Medicine and Health, the University of Sydney, Sydney, New South Wales, Australia., Kizana E; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia.; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Kumar S; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia., Gray PP; Australian Institute for Bioengineering and Nanotechnology, the University of Queensland, St Lucia, Queensland, Australia., Chong JJH; Centre for Heart Research, the Westmead Institute for Medical Research, the University of Sydney, Westmead, New South Wales, Australia. james.chong@sydney.edu.au.; Department of Cardiology, Westmead Hospital, Westmead, New South Wales, Australia. james.chong@sydney.edu.au.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2024 Feb; Vol. 3 (2), pp. 145-165. Date of Electronic Publication: 2024 Feb 06.