Evaluation of the Xpert MTB Host Response assay for the triage of patients with presumed pulmonary tuberculosis: a prospective diagnostic accuracy study in Viet Nam, India, the Philippines, Uganda, and South Africa

Autor: Thangakunam, Balamugesh, Shankar, Deepa, Ernest, Vinita, John, Flavita, Karthikeyan, Bharath, Sekar, Reena, Mangal, Divya, Vijayasree, Sai, Sankar, Swetha, Shibiya, Mary, Gajendran, Priyadarshini, Elango, Shanmugasundaram, Sekar, Rajasekar, Almonte, Jared, Basilio, Ramon, Cariaga, Asella Ruvijean, Destura, Raul, Dalay, Victoria, Dayawon, Karlo, Gelina, Darecil, Goleña, Joseph Aldwin, Golla, Maria Marissa, Ilagan, Gidalthi Jonathan, Lim, Dodge, Pabruada, Angelita, Reyes, Annalyn, Reyes, Roeus Vincent Arjay G., Tonquin, Maricef, Derendinger, Brigitta, Hendrikse, Megan, Okunola, Anna, Palmer, Zaida, Andama, Alfred, Kisakye, Esther, Mukwatamundu, Job, Mwebe, Sandra, Nakaye, Martha, Worodria, William, Nyawere, Justine, Bukirwa, Alice, Mangeni, Wilson, Ssonko, John Baptist, Nakaweesa, Annet, Nassuna, Irene, Nekesa, Irene, Katumba, David, Asege, Lucy, Nalugwa, Talemwa, Dang, Hai, Dinh, Luong, Doan, Thien, Do, Hang, Do, Tam, Le, Hien, Le, Nguyet, Nguyen, Anh, Nguyen, Dong, Nguyen, Hanh, Nguyen, Hoang, Nguyen, Thanh, Pham, Nam, Pham, Thuong, Phan, Ha, Trinh, Trang, Castro, Robert, Cook, Catherine, Mochizuki, Tessa, Kato-Maeda, Midori, Nathavitharana, Ruvandhi, Nolan, Kevin, Olaru, Ioana-Diana, Castro Noriega, Maria del Mar, Yerlikaya, Seda, Gupta-Wright, Ankur ^{*, *}, Ha, Huy ^*, Abdulgadar, Shima, Crowder, Rebecca, Emmanuel, Jerusha, Marcelo, Danaida, Phillips, Patrick P J, Christopher, Devasahayam Jesudas, Nhung, Nguyen Viet, Theron, Grant, Yu, Charles, Nahid, Payam, Cattamanchi, Adithya, Denkinger, Claudia M ^*

Publikováno v: In The Lancet Global Health February 2024 12(2):e226-e234

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Characterization of oral swab samples for diagnosis of pulmonary tuberculosis

Autor: William Worodria, Adithya Cattamanchi, Akos Somoskovi, David Katumba, Kyle J. Minch, Christine Bachman, Burkot Stephen Thomas Graves, Derek Bell, Anne-Laure M. Le Ny, Rachel C. Wood, Damian Madan, Fred C. Semitala, Kris M. Weigel, Corrie Ortega, Gleda Hermansky, Lucy Asege, Sandra Mwebe, Gerard A. Cangelosi, Rita N. Olson, Alfred Andama, Alaina M. Olson, Kevin Paul Flood Nichols, Jerry Mulondo, Martha Nakaye, Mukwatamundu Job

Publikováno v: PloS one, vol 16, iss 5
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0251422 (2021)

Oral swab analysis (OSA) has been shown to detectMycobacterium tuberculosis(MTB) DNA in patients with pulmonary tuberculosis (TB). In previous analyses, qPCR testing of swab samples collected from tongue dorsa was up to 93% sensitive relative to sput

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b564745a2f7c95d1d0d56da7cf70901e
https://escholarship.org/uc/item/4fd8f713

New manual qPCR assay validated on tongue swabs collected and processed in Uganda shows sensitivity that rivals sputum-based molecular TB diagnostics.

Autor: Steadman A, Andama A, Ball A, Mukwatamundu J, Khimani K, Mochizuki T, Asege L, Bukirwa A, Kato JB, Katumba D, Kisakye E, Mangeni W, Mwebe S, Nakaye M, Nasuna I, Nyawere J, Visente D, Cook C, Nalugwa T, Bachman CM, Semitalia F, Weigl BH, Connelly J, Worodria W, Cattamanchi A

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Aug 15. Date of Electronic Publication: 2023 Aug 15.