Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres.

Autor: Mariana C Gadaleta, Mukund M Das, Hideki Tanizawa, Ya-Ting Chang, Ken-ichi Noma, Toru M Nakamura, Eishi Noguchi

Publikováno v: PLoS Genetics, Vol 12, Iss 3, p e1005943 (2016)

Genomic instability associated with DNA replication stress is linked to cancer and genetic pathologies in humans. If not properly regulated, replication stress, such as fork stalling and collapse, can be induced at natural replication impediments pre

Externí odkaz: https://doaj.org/article/c6127aa80e8249ceb911268fa59fb26b

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres

Autor: Seung Woo Lee, Eishi Noguchi, Paul M. Lieberman, Zhong Deng, Adam R. Leman, Jayaraju Dheekollu, Mukund M. Das

Publikováno v: Cell Cycle. 11:2337-2347

A variety of telomere protection programs are utilized to preserve telomere structure. However, the complex nature of telomere maintenance remains elusive. The Timeless protein associates with the replication fork and is thought to support efficient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b39f7409a2bb51b6a9219a967241de8
https://doi.org/10.4161/cc.20810

Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres

Autor: Eishi Noguchi, Ken-ichi Noma, Hideki Tanizawa, Mukund M. Das, Ya Ting Chang, Mariana C. Gadaleta, Toru Nakamura

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005943 (2016)

Genomic instability associated with DNA replication stress is linked to cancer and genetic pathologies in humans. If not properly regulated, replication stress, such as fork stalling and collapse, can be induced at natural replication impediments pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd70597fe81cc987c51bd14fe3bee94
https://doi.org/10.1371/journal.pgen.1005943

Left Atrial Strain Impairment Precedes Geometric Remodeling as a Marker of Post-Myocardial Infarction Diastolic Dysfunction.

Autor: Kim J; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York. Electronic address: jik9027@med.cornell.edu., Yum B; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., Palumbo MC; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., Sultana R; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., Wright N; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., Das M; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., You C; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., Moskowitz CS; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York., Levine RA; Department of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Devereux RB; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York., Weinsaft JW; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, New York; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

Publikováno v: JACC. Cardiovascular imaging [JACC Cardiovasc Imaging] 2020 Oct; Vol. 13 (10), pp. 2099-2113. Date of Electronic Publication: 2020 Aug 19.

Development of novel machine learning model for right ventricular quantification on echocardiography-A multimodality validation study.

Autor: Beecy AN; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Bratt A; Department of Radiology, Mayo Clinic (Minnesota), Rochester, MN, USA., Yum B; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Sultana R; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Das M; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Sherifi I; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Devereux RB; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Weinsaft JW; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Kim J; Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.

Publikováno v: Echocardiography (Mount Kisco, N.Y.) [Echocardiography] 2020 May; Vol. 37 (5), pp. 688-697. Date of Electronic Publication: 2020 May 12.