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Akademický článek

Frequent Inactivation of Secreted Frizzled-Related Protein 2 during the Development of Cervical Carcinoma: Identification of Susceptible Alleles and Clinical Implications

Autor: Sudip Samadder, Debolina Pal, Anirban Roychowdhury, Arindam Dutta, Mukta Basu, Sankhadeep Dutta, Anup Roy, Ranajit Kumar Mandal, Susanta Roychoudhury, Chinmay Kumar Panda

Publikováno v: Journal of Radiation and Cancer Research, Vol 15, Iss 2, Pp 55-63 (2024)

Background: In this study, importance of SFRP2, wnt stem cell renewal pathway antagonist, in the development of cervical cancer (CACX) was evaluated. Aims and Objectives: Alterations (expression/ methylation/ deletion) of SFRP2 were analysed in prima

Externí odkaz: https://doaj.org/article/575d82d5c6cf4e7c8a1b83b5849f9594

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Akademický článek

Association of Augmented Immune-Staining of G-Quadruplex Tertiary DNA Structure in Chemo-Tolerant TNBC with Downregulation of WNT/Epidermal Growth Factor Receptor Pathway receptor Genes: A Pilot Clinicopathological Study

Autor: Saimul Islam, Mukta Basu, Anup Roy, Neyaz Alam, Chinmay Kumar Panda

Publikováno v: Journal of Radiation and Cancer Research, Vol 14, Iss 1, Pp 14-20 (2023)

Purpose: The aim of the study is to understand the involvement of G-Quadruplex (G-Q) structures in altering the expression profile of WNT/epidermal growth factor receptor (EGFR) pathway receptor genes in chemo-tolerant Triple Negative Breast Cancer (

Externí odkaz: https://doaj.org/article/37b41a5f81c442d38913b637bcd59cf2

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PTPRJ is downregulated in cervical squamous cell carcinoma

Autor: Anirban Roychowdhury, Mukta Basu, Debolina Pal, Priyanka Dutta, Sudip Samadder, Ranajit Mondal, Anup Kumar Roy, Susanta Roychoudhury, Chinmay Kumar Panda

Publikováno v: Journal of genetics. 101

Squamous cell carcinoma of the uterine cervix (CSCC) is one of the leading causes of death in Indian women. Protein tyrosine phosphatase receptor (PTPR) type J (also known as DEP1) is a recently reported tumour suppressor receptor phosphatase. Critic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed2af55b3a1b4e6d4b9afd94da82651
https://pubmed.ncbi.nlm.nih.gov/35791609

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Differential Wnt-β- catenin pathway activation in HPV positive and negative oral epithelium is transmitted during head and neck tumorigenesis: clinical implications

Autor: Jayanta Chakrabarti, Debalina Mukhopadhyay, Anirban Roychowdhury, Kabita Chatterjee, Mukta Basu, Chinmay Kumar Panda, Balarko Chakraborty, Neyaz Alam

Publikováno v: Medical Microbiology and Immunology. 210:49-63

The aim of this study is to understand the association of HPV infection and wnt-β-catenin self-renewal pathway in development of head and neck squamous cell carcinoma (HNSCC). For this reason, the molecular profiles (methylation/deletion/expression)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5df99064170c134b049f2caab1ac29
https://doi.org/10.1007/s00430-020-00697-9

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Reduction of nuclear Y654‐p‐β‐catenin expression through SH3GL2‐meditated downregulation of EGFR in chemotolerance TNBC: Clinical and prognostic importance

Autor: Md. Saimul Islam, Susanta Roychoudhury, Mukta Basu, Chinmay Kumar Panda, Neyaz Alam, Anup Roy, Hemantika Dasgupta

Publikováno v: Journal of Cellular Physiology. 235:8114-8128

Triple negative breast cancer (TNBC) originates from a less differentiated ductal cell of breast, which is less sensitive to chemotherapy. The chemotolerance mechanism of TNBC has not yet been studied in detail. For this reason, molecular profiles (e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df149fde22ad92d10192f9c6fef90a1f
https://doi.org/10.1002/jcp.29466

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Differential operation of MLH1/MSH2 and FANCD2 crosstalk in chemotolerant bladder carcinoma: a clinical and therapeutic intervening study

Autor: Mukta Basu, Debalina Mukhopadhyay, Balarko Chakraborty, Sabnam Ghosh, Dilip Kumar Pal, Amlan Ghosh, Chinmay Kumar Panda

Publikováno v: Molecular and cellular biochemistry.

We aimed to understand the crosstalk between mismatch repair (MMR) and FA-BRCA pathway in primary bladder carcinoma (BlCa) samples as well as in chemotolerant cell line. We analysed the genetic alterations of MLH1 and MSH2 (MMR-related genes) and aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1eeeeb4325a0bdeb62cc88e663fd46c
https://pubmed.ncbi.nlm.nih.gov/36434146

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