Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mukesh L. Patel"'
Autor:
Nigel Greene, Lilia Fisk, Russell T. Naven, Reine R. Note, Mukesh L. Patel, Dennis J. Pelletier
Publikováno v:
Chemical research in toxicology. 23(7)
Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd76c6e90ffddf6cf46affcd7099bbf
https://pubmed.ncbi.nlm.nih.gov/20553011
https://pubmed.ncbi.nlm.nih.gov/20553011
Publikováno v:
ChemInform. 41
Hepatotoxicity is a major cause of pharmaceutical drug attrition and is also a concern within other chemical industries. In silico approaches to the prediction of hepatotoxicity are an important tool in the early identification of adverse effects in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5591f150211d07f91aaeb7f5e9507c20
https://doi.org/10.1002/chin.201009263
https://doi.org/10.1002/chin.201009263
Publikováno v:
Drug Metabolism Reviews. Feb2007 Supplement 1, Vol. 39, p1-388. 388p.
Publikováno v:
Chemistry & Biodiversity; Nov2009, Vol. 6 Issue 11, p2107-2114, 8p
Publikováno v:
Toxicology Letters. 205:S95
Receptor (PR) from the steroid hormone receptors superfamily. AR binding has been associated with i) the transient stimulation of cell proliferation and consequent tumour formation in the prostate of rats and humans [3], and also in organs such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62f3d1e93e9fb9c8241ec083ea407326
https://doi.org/10.1016/j.toxlet.2011.05.347
https://doi.org/10.1016/j.toxlet.2011.05.347