Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mukesh K. Jaiswal"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nuc
Externí odkaz:
https://doaj.org/article/80c1e35c8d404cf1bc2c92f509ad31c5
Publikováno v:
Biology of Reproduction. 99:546-555
Preterm birth accounts for the majority of neonatal morbidity and mortality in the developed world. A significant proportion of cases of spontaneous preterm labor are attributable to infections within gestational tissues. Surfactant protein A (SP-A),
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nuc
Autor:
Ramayee Periakaruppan, Jordyn Ginter, Safaa A. Ibrahim, Corina Sandulescu, James Dolan, Sahithi Pamarthy, Kenneth D. Beaman, Gajendra K. Katara, Arpita Kulshrestha, Alice Gilman-Sachs, Mukesh K. Jaiswal
Publikováno v:
Molecular Oncology. 10:789-805
Development of resistance to platinum compounds significantly hinders successful ovarian cancer (OVCA) treatment. In tumor cells, dysregulated pH gradient across cell membranes is a key physiological mechanism of metastasis/chemo‐resistance. These
Autor:
Kenneth D. Beaman, Varkha Agrawal, Sylvia Schneiderman, Mukesh K. Jaiswal, Alice Gilman-Sachs, Svetlana Dambaeva, Emmet Hirsch, Gajendra K. Katara
Preterm birth is widespread and causes 35% of all neonatal deaths. Infants who survive face potential long-term complications. A major contributing factor of preterm birth is infection. We investigated the role of interleukin 22 (IL22) as a potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ffb8211459bc9cc8a92a19b2f20f71
https://europepmc.org/articles/PMC6669419/
https://europepmc.org/articles/PMC6669419/
Autor:
Mukesh K. Jaiswal, Varkha Agrawal, Alice Gilman-Sachs, Gérard Chaouat, Kenneth D. Beaman, Sahithi Pamarthy, Gajendra K. Katara, Arpita Kulshrestha
Publikováno v:
Journal of Reproductive Immunology. 112:38-45
The a2 isoform of vacuolar-ATPase (ATP6V0A2, referred to as a2V) is required for normal spermatogenesis and maturation of sperm. Treatment of male mice with anti-a2V disturbs the testicular cytokine/chemokine balance and leads to severe deficiencies
Autor:
Gajendra K. Katara, Mukesh K. Jaiswal, Safaa A. Ibrahim, Kenneth D. Beaman, Magdy A. Amin, Arpita Kulshrestha
Publikováno v:
Oncotarget
In invasive breast cancer, tumor associated neutrophils (TAN) represent a significant portion of the tumor mass and are associated with increased angiogenesis and metastasis. Identifying the regulatory factors that control TAN behavior will help in d
Autor:
Alice Gilman-Sachs, Kenneth D. Beaman, Gajendra K. Katara, Sahithi Pamarthy, Arpita Kulshreshtha, Mukesh K. Jaiswal
Publikováno v:
Oncotarget
Triple Negative Breast Cancer (TNBC) is a subtype of breast cancer with poor prognosis for which no targeted therapies are currently available. Notch signaling has been implicated in breast cancer but the factors that control Notch in TNBC are unknow
Autor:
Mukesh K. Jaiswal, Alice Gilman-Sachs, Kenneth D. Beaman, Arpita Kulshrestha, Gajendra K. Katara, Sahithi Pamarthy
Publikováno v:
Oncogene. 35:1058-1065
In cancer cells, vacuolar ATPase (V-ATPase), a multi-subunit enzyme, is expressed on the plasma as well as vesicular membranes and critically influences metastatic behavior. The soluble, cleaved N-terminal domain of V-ATPase a2 isoform is associated
Autor:
Mukesh K. Jaiswal, Alice Gilman-Sachs, Evangelos Ntrivalas, Kenneth D. Beaman, Leyla Akman-Anderson, Anjali Tikoo
Publikováno v:
Journal of Leukocyte Biology. 97:1121-1131
Neutrophils kill microorganisms by inducing exocytosis of granules with antibacterial properties. Four isoforms of the “a” subunit of V-ATPase—a1V, a2V, a3V, and a4V—have been identified. a2V is expressed in white blood cells, that is, on the