Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mujmmail Ahmed"'
Autor:
Ezequiel Dantas, Anirudh Murthy, Tanvir Ahmed, Mujmmail Ahmed, Shakti Ramsamooj, Maurice A. Hurd, Tiffany Lam, Murtaza Malbari, Christopher Agrusa, Olivier Elemento, Chen Zhang, Darryl J. Pappin, Timothy E. McGraw, Brendon M. Stiles, Nasser K. Altorki, Marcus D. Goncalves
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background Lung cancer remains the major cause of cancer‐related deaths worldwide. Early stages of lung cancer are characterized by long asymptomatic periods that are ineffectively identified with the current screening programs. This defic
Externí odkaz:
https://doaj.org/article/9f3f0facc0d04731a5086808193bc9a9
Autor:
Andre Lima Queiroz, Ezequiel Dantas, Shakti Ramsamooj, Anirudh Murthy, Mujmmail Ahmed, Elizabeth R. M. Zunica, Roger J. Liang, Jessica Murphy, Corey D. Holman, Curtis J. Bare, Gregory Ghahramani, Zhidan Wu, David E. Cohen, John P. Kirwan, Lewis C. Cantley, Christopher L. Axelrod, Marcus D. Goncalves
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Cancer-associated cachexia is characterized by loss of body weight, skeletal muscle and adipose tissue which relates to higher mortality in cancer patients. Here, the authors show in a lung cancer murine model that both ActRIIB signalling inhibition
Externí odkaz:
https://doaj.org/article/dc0384978f5f41459c1d29179df85639
Autor:
Andre Lima Queiroz, Ezequiel Dantas, Shakti Ramsamooj, Anirudh Murthy, Mujmmail Ahmed, Elizabeth R. M. Zunica, Roger J. Liang, Jessica Murphy, Corey D. Holman, Curtis J. Bare, Gregory Ghahramani, Zhidan Wu, David E. Cohen, John P. Kirwan, Lewis C. Cantley, Christopher L. Axelrod, Marcus D. Goncalves
Publikováno v:
Nature communications. 13(1)
Cancer cachexia is a common, debilitating condition with limited therapeutic options. Using an established mouse model of lung cancer, we find that cachexia is characterized by reduced food intake, spontaneous activity, and energy expenditure accompa