Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mui Ling Khoo"'
Autor:
David P. Sheela, Beáta Sperlágh, Tiong Wei Tan, Mui Ling Khoo, Yi Yuan Chua, Ruth Deme, Balázs Balogh, Kálmán Magyar, Flóra Gölöncsér, Christina L. L. Chai, Paul B. Huleatt, Péter Mátyus, Han Kiat Ho, Rou Shen Liew
Publikováno v:
Journal of Medicinal Chemistry. 58:1400-1419
To develop novel neuroprotective agents, a library of novel arylalkenylpropargylamines was synthesized and tested for inhibitory activities against monoamine oxidases. From this, a number of highly potent and selective monoamine oxidase B inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b2e214d527c4275d8ea0be05e54fd
https://doi.org/10.1021/jm501722s
https://doi.org/10.1021/jm501722s
Autor:
Dizhong Chen, Mui Ling Khoo, Joyce Wei Wei Chang, Kee Chuan Goh, Xin Liu, Anders Poulsen, Siok Kun Goh, Kay Lin Goh, Kanda Sangthongpitag, Niefang Yu, Lye Pek Ling, Zahid Bonday, Changyong Hu, Xukun Wang, Xiaofeng Wu, Brian Dymock, Hwee Hoon Khng, Eric T. Sun, Haishan Wang, Melvin Ng, Lijuan Fang, Ethirajulu Kantharaj, Weiping Deng, Jeanette Marjorie Wood, Ting Lu, Ken Chi Lik Lee, Pauline Yeo
Publikováno v:
Journal of Medicinal Chemistry. 54:4694-4720
A series of 3-(1,2-disubstituted-1H-benzimidazol-5-yl)-N-hydroxyacrylamides (1) were designed and synthesized as HDAC inhibitors. Extensive SARs have been established for in vitro potency (HDAC1 enzyme and COLO 205 cellular IC(50)), liver microsomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c07c03162bfd202810c8090e495663
https://doi.org/10.1021/jm2003552
https://doi.org/10.1021/jm2003552
Autor:
G. Paul Savage, Mariana El Sous, Peter J. Scammells, Timothy E. Adams, Georgina A. Holloway, Sebastian Hirner, Bill C. Hawkins, Mui Ling Khoo, David J. Owen, Mark A. Rizzacasa
Publikováno v:
Journal of the American Chemical Society. 131:1607-1616
Total synthesis of the anticancer 1,4-dioxane containing natural products silvestrol (1) and episilvestrol (2) is described by an approach based on the proposed biosynthesis of these novel compounds. The key steps included an oxidative rearrangement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88332edfcc593d7a82ea4f5f48045e2
https://doi.org/10.1021/ja808402e
https://doi.org/10.1021/ja808402e
Autor:
Mui Ling Khoo, Mark A. Rizzacasa, Peter J. Scammells, Mariana El Sous, David Owen, Georgina A. Holloway
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38ed1ea8c18b6dc1d61ffd7c3e6ccf13
https://doi.org/10.1002/chin.200805216
https://doi.org/10.1002/chin.200805216
Autor:
Baranyi, Mária, Porceddu, Pier Francesca, Gölöncsér, Flóra, Kulcsár, Szabina, Otrokocsi, Lilla, Kittel, Ágnes, Pinna, Annalisa, Frau, Lucia, Huleatt, Paul B., Mui-Ling Khoo, Chai, Christina L. L., Dunkel, Petra, Mátyus, Peter, Morelli, Micaela, Sperlágh, Beáta
Publikováno v:
Molecular Neurodegeneration; 1/13/2016, Vol. 11, p1-21, 21p, 1 Diagram, 2 Charts, 7 Graphs
Autor:
Baranyi, Mária, Porceddu, Pier, Gölöncsér, Flóra, Kulcsár, Szabina, Otrokocsi, Lilla, Kittel, Ágnes, Pinna, Annalisa, Frau, Lucia, Huleatt, Paul, Mui-Ling Khoo, Chai, Christina, Dunkel, Petra, Mátyus, Peter, Morelli, Micaela, Sperlágh, Beáta
The duration of action of SZV558 (10 mg/kg) i.p. and the effect of its metabolites on endogenous dopamine content in the striatum and on the survival of animals after in vivo MPTP treatment (DOC 31 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0011c2b3a7ae7e999e89a9670182703
Autor:
Beáta Sperlágh, Lilla Otrokocsi, Christina L. L. Chai, Petra Dunkel, Ágnes Kittel, Pier Francesca Porceddu, Micaela Morelli, Mária Baranyi, Paul B. Huleatt, Péter Mátyus, Lucia Frau, Szabina Kulcsár, Mui-Ling Khoo, Flóra Gölöncsér, Annalisa Pinna
Publikováno v:
Molecular Neurodegeneration
Background Mitochondrial dysfunction, oxidative stress and their interplay are core pathological features of Parkinson’s disease. In dopaminergic neurons, monoamines and their metabolites provide an additional source of reactive free radicals durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d315920ab4aeeec58578e4049e9277f8
Autor:
Mui Ling Khoo, Mariana El Sous, Mark A. Rizzacasa, David J. Owen, Peter J. Scammells, Georgina A. Holloway
Publikováno v:
Monash University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4055336d8642e5af731280b7bcfca186
https://research.monash.edu/en/publications/6c3f4719-d2f7-4f2d-91fb-977c4aed51bd
https://research.monash.edu/en/publications/6c3f4719-d2f7-4f2d-91fb-977c4aed51bd
Autor:
Baranyi, Mária, Porceddu, Pier, Gölöncsér, Flóra, Kulcsár, Szabina, Otrokocsi, Lilla, Kittel, Ágnes, Pinna, Annalisa, Frau, Lucia, Huleatt, Paul, Mui-Ling Khoo, Chai, Christina, Dunkel, Petra, Mátyus, Peter, Morelli, Micaela, Sperlágh, Beáta
The duration of action of SZV558 (10 mg/kg) i.p. and the effect of its metabolites on endogenous dopamine content in the striatum and on the survival of animals after in vivo MPTP treatment (DOC 31 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1760177738a14c4efa0e45bea475ef0c
Autor:
Adams, Tim E.1, El Sous, Mariana2, Hawkins, Bill C.2, Hirner, Sebastian2, Holloway, Georgina3, Mui Ling Khoo2, Owen, David J.4, Savage, G. Paul1, Scammells, Peter J.3, Rizzacasa, Mark A.2 masr@unimelb.edu.au
Publikováno v:
Journal of the American Chemical Society. 2/4/2009, Vol. 131 Issue 4, p1607-1616. 10p.