Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Muhannad Shweash"'
Autor:
Thikryat Neamatallah, Shilan Jabbar, Rothwelle Tate, Juliane Schroeder, Muhannad Shweash, James Alexander, Robin Plevin
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3434 (2019)
Background: Mitogen-activated protein kinase phosphatase-2 (MKP-2) is a type 1 nuclear dual specific phosphatase (DUSP-4). It plays an important role in macrophage inflammatory responses through the negative regulation of Mitogen activated protein ki
Externí odkaz:
https://doaj.org/article/6d4cd45451e64d6fa0783547800d1c9b
Autor:
Mashael S Al-Mutairi, Laurence C Cadalbert, H Adrienne McGachy, Muhannad Shweash, Juliane Schroeder, Magdalena Kurnik, Callum M Sloss, Clare E Bryant, James Alexander, Robin Plevin
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001192 (2010)
In this study we generated a novel dual specific phosphatase 4 (DUSP4) deletion mouse using a targeted deletion strategy in order to examine the role of MAP kinase phosphatase-2 (MKP-2) in immune responses. Lipopolysaccharide (LPS) induced a rapid, t
Externí odkaz:
https://doaj.org/article/8b370344e4b845929912de640584ece4
Publikováno v:
International Journal of Life Science and Pharma Research.
Metformin is considered as an oral anti-diabetes agent. It is regularly used as a first-drug for the controlling of type-2 Diabetes Mellitus (T2DM). However, we aimed to evaluate whether the inflammatory biomarkers C - reactive protein (CRP), Complem
Publikováno v:
International Journal of Drug Delivery Technology. 10:114-118
This study was carried out at Baghdad hospital in, for the period from November 2018 to July 2019. The study included (151) aborted obese women whose ages ranged between (18–41) years with positive Toxoplasma gondii infection. They were divided int
Autor:
Mohanad Adel Mohammed, Ashwaq Talib Duraij, Muntaha Qasim Hendi, Muhannad Shweash, Ghuran Mahdi Salih, Hayder Adnan Fawzi, Mushtaq Talib Abed
Publikováno v:
International Journal of Research in Pharmaceutical Sciences. 10:2095-2098
Vitamin D is an essential vitamin that regulates many biological processes and involved in the activity of many organs like the skin, bone, kidney, etc. ferritin is an essential marker for assessment of anemic status. The current study aimed to
Publikováno v:
Annals of Tropical Medicine and Public Health. 23
Autor:
Emma Torrance, Muhannad Shweash, Ahmed Lawan, Juliane Schroeder, Sulaiman Alnasser, Sameer Al-Harthi, Thikryat Neamatallah, Robin Plevin
Publikováno v:
Biochemical Society Transactions. 40:235-239
The MKPs (mitogen-activated protein kinase phosphatases) are a family of at least ten DUSPs (dual-specificity phosphatases) which function to terminate the activity of the MAPKs (mitogen-activated protein kinases). Several members have already been d
Autor:
James Alexander, Jeremy C. Mottram, H. Adrienne McGachy, Muhannad Shweash, Owain R. Millington, Robin Plevin, Clare E. Bryant, Juliane Schroeder, Thikryat Neamatallah
Publikováno v:
Molecular Immunology
Highlights ► TLR-4 activation by Leishmania mexicana promastigotes and CPB-deficient amastigotes. ► Prolonged, TLR-4 dependent iNOS and COX-2 expression by L. mexicana promastigotes. ► Enhanced TLR-4 dependent-arginase-1 expression. ► Regulat
Publikováno v:
The Journal of Immunology. 185:4525-4534
The role of progesterone in modulating dendritic cell (DC) function following stimulation of different TLRs is relatively unknown. We compared the ability of progesterone to modulate murine bone marrow-derived DC cytokine production (IL-6 and IL-12)
Publikováno v:
Asian Journal of Pharmaceutical and Clinical Research. 11:199
Objective: Cancer ovary is one of the fatal gynecologic malignancies worldwide. Since breast cancer (BRCA) genes are considered tumor suppressor genes and play important roles in cancer by repairing of chromosomal damage with the error repair of DNA