Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Muhammed Murtaza"'
Autor:
Patricia Filippsen Favaro, Samuel D. Stewart, Bradon R. McDonald, Jacob Cawley, Tania Contente-Cuomo, Shukmei Wong, William P. D. Hendricks, Jeffrey M. Trent, Chand Khanna, Muhammed Murtaza
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Comparative studies of naturally occurring canine cancers have provided new insight into many areas of cancer research. Development and validation of circulating tumor DNA (ctDNA) analysis in pet dogs can help address diagnostic needs in vet
Externí odkaz:
https://doaj.org/article/cc29ebdfe079466b908868b23dd9fa40
Autor:
Shukmei Wong, E J Ehrhart, Samuel Stewart, Victoria Zismann, Jacob Cawley, Rebecca Halperin, Natalia Briones, Keith Richter, Karthigayini Sivaprakasam, Nieves Perdigones, Tania Contente-Cuomo, Salvatore Facista, Jeffrey M Trent, Muhammed Murtaza, Chand Khanna, William P D Hendricks
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0264986 (2022)
Cancer genomic heterogeneity presents significant challenges for understanding oncogenic processes and for cancer's clinical management. Variation in driver mutation frequency between patients with the same tumor type as well as within an individual
Externí odkaz:
https://doaj.org/article/62e231b6cdc64d4faee96910a1df5788
Autor:
Jason Chibuk, Andi Flory, Kristina M. Kruglyak, Nicole Leibman, Alexis Nahama, Nilesh Dharajiya, Dirk van den Boom, Taylor J. Jensen, Jeffrey S. Friedman, M. Richard Shen, Francisco Clemente-Vicario, Ilya Chorny, John A. Tynan, Katherine M. Lytle, Lauren E. Holtvoigt, Muhammed Murtaza, Luis A. Diaz, Dana W. Y. Tsui, Daniel S. Grosu
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Cancer is the leading cause of death in dogs, in part because many cases are identified at an advanced stage when clinical signs have developed, and prognosis is poor. Increased understanding of cancer as a disease of the genome has led to the introd
Externí odkaz:
https://doaj.org/article/1a670dcb55b249c9b2b7661f3b596c77
Autor:
Havell Markus, Tania Contente-Cuomo, Maria Farooq, Winnie S. Liang, Mitesh J. Borad, Shivan Sivakumar, Simon Gollins, Nhan L. Tran, Harshil D. Dhruv, Michael E. Berens, Alan Bryce, Aleksandar Sekulic, Antoni Ribas, Jeffrey M. Trent, Patricia M. LoRusso, Muhammed Murtaza
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Pre-analytical factors can significantly affect circulating cell-free DNA (cfDNA) analysis. However, there are few robust methods to rapidly assess sample quality and the impact of pre-analytical processing. To address this gap and to evalua
Externí odkaz:
https://doaj.org/article/754bebe0d60d4db2a753e90d4a1c1a88
Autor:
Leticia De Mattos-Arruda, Stephen-John Sammut, Edith M. Ross, Rachael Bashford-Rogers, Erez Greenstein, Havell Markus, Sandro Morganella, Yvonne Teng, Yosef Maruvka, Bernard Pereira, Oscar M. Rueda, Suet-Feung Chin, Tania Contente-Cuomo, Regina Mayor, Alexandra Arias, H. Raza Ali, Wei Cope, Daniel Tiezzi, Aliakbar Dariush, Tauanne Dias Amarante, Dan Reshef, Nikaoly Ciriaco, Elena Martinez-Saez, Vicente Peg, Santiago Ramon y Cajal, Javier Cortes, George Vassiliou, Gad Getz, Serena Nik-Zainal, Muhammed Murtaza, Nir Friedman, Florian Markowetz, Joan Seoane, Carlos Caldas
Publikováno v:
Cell Reports, Vol 27, Iss 9, Pp 2690-2708.e10 (2019)
Summary: The detailed molecular characterization of lethal cancers is a prerequisite to understanding resistance to therapy and escape from cancer immunoediting. We performed extensive multi-platform profiling of multi-regional metastases in autopsie
Externí odkaz:
https://doaj.org/article/caa33a84a1a642cdaf3f8314c1e4dd94
Autor:
Dana Wai Yi Tsui, Muhammed Murtaza, Alvin Seng Cheong Wong, Oscar M Rueda, Christopher G Smith, Dineika Chandrananda, Ross A Soo, Hong Liang Lim, Boon Cher Goh, Carlos Caldas, Tim Forshew, Davina Gale, Wei Liu, James Morris, Francesco Marass, Tim Eisen, Tan Min Chin, Nitzan Rosenfeld
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 6, Pp n/a-n/a (2018)
Abstract Tumour heterogeneity leads to the development of multiple resistance mechanisms during targeted therapies. Identifying the dominant driver(s) is critical for treatment decision. We studied the relative dynamics of multiple oncogenic drivers
Externí odkaz:
https://doaj.org/article/359abd7345a3480bbf157d3f3b813302
Autor:
Roland F Schwarz, Charlotte K Y Ng, Susanna L Cooke, Scott Newman, Jillian Temple, Anna M Piskorz, Davina Gale, Karen Sayal, Muhammed Murtaza, Peter J Baldwin, Nitzan Rosenfeld, Helena M Earl, Evis Sala, Mercedes Jimenez-Linan, Christine A Parkinson, Florian Markowetz, James D Brenton
Publikováno v:
PLoS Medicine, Vol 12, Iss 2, p e1001789 (2015)
BackgroundThe major clinical challenge in the treatment of high-grade serous ovarian cancer (HGSOC) is the development of progressive resistance to platinum-based chemotherapy. The objective of this study was to determine whether intra-tumour genetic
Externí odkaz:
https://doaj.org/article/0a04b45ee3a2448488392ea351cd23be
Autor:
Corine M Beaufort, Jean C A Helmijr, Anna M Piskorz, Marlous Hoogstraat, Kirsten Ruigrok-Ritstier, Nicolle Besselink, Muhammed Murtaza, Wilfred F J van IJcken, Anouk A J Heine, Marcel Smid, Marco J Koudijs, James D Brenton, Els M J J Berns, Jozien Helleman
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e103988 (2014)
Epithelial ovarian cancer is a highly heterogeneous disease and remains the most lethal gynaecological malignancy in the Western world. Therapeutic approaches need to account for inter-patient and intra-tumoural heterogeneity and detailed characteriz
Externí odkaz:
https://doaj.org/article/89fef8c147544e4ca580af119453cff1
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5827 (2009)
BACKGROUND:Morbidity associated with primary headache disorders is a major public health problem with an overall prevalence of 46%. Tension-type headache and migraine are the two most prevalent causes. However, headache has not been sufficiently stud
Externí odkaz:
https://doaj.org/article/a834c59ed9804eb5ad547811e5b24d91
Autor:
ÇAVUŞ, Muhammed Murtaza1 murtazacavus@hotmail.com
Publikováno v:
Islami Ilimler Dergisi. bahar2023, Vol. 18 Issue 1, p296-282. 15p.