Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Muhammed Iraqi"'
Autor:
Walid Shalata, Daniel Levin, Janna Fridman, Victoria Makarov, Muhammed Iraqi, Mitchell Golosky, Keren Rouvinov, Waleed Kian, Alexander Yakobson
Publikováno v:
Current Oncology, Vol 29, Iss 2, Pp 989-1000 (2022)
In the following report, we describe 11 patients with various diagnoses and different treatment statuses (newly diagnosed, receiving treatment, or follow-up) of oncological diseases (breast, lymphoma, melanoma, and head and neck cancers). The patient
Externí odkaz:
https://doaj.org/article/09d8358226f54fed8e17a94cea92c445
Autor:
Aner Ottolenghi, Priyanka Bolel, Rhitajit Sarkar, Yariv Greenshpan, Muhammed Iraqi, Susmita Ghosh, Baisali Bhattacharya, Zoe V. Taylor, Kiran Kundu, Olga Radinsky, Roi Gazit, David Stepensky, Ron N. Apte, Elena Voronov, Angel Porgador
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract IL-2 is the master-regulator cytokine for T cell dependent responses and is crucial for proliferation and survival of T cells. However, IL-2-based treatments remained marginal, in part due to short half-life. Thus, we aimed to extend IL-2 ha
Externí odkaz:
https://doaj.org/article/ad6cc7eb08a2453fb99bf074bf0f2812
Autor:
Muhammed Iraqi, Priyanka Bolel, Rhitajit Sarkar, Baisali Bhattacharya, Muhammad Abu Ahmad, Avishay Edri, Laila C. Roisman, Moshe Elkabets, Walid Shalata, Nir Peled, Angel Porgador
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14054 (2022)
Lung cancer cells in the tumor microenvironment facilitate immune evasion that leads to failure of conventional chemotherapies, despite provisionally decided on the genetic diagnosis of patients in a clinical setup. The current study follows three lu
Externí odkaz:
https://doaj.org/article/249f0a43fe804b55809a5a0dfe4339ae
Autor:
Muhammed Iraqi, Avishay Edri, Yariv Greenshpan, Oron Goldstein, Noa Ofir, Priyanka Bolel, Muhammad Abu Ahmad, Miri Zektser, Kerry S. Campbell, Ory Rouvio, Roi Gazit, Angel Porgador
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4717 (2022)
Multiple Myeloma (MM) is a devastating malignancy that evades immune destruction using multiple mechanisms. The NKp44 receptor interacts with PCNA (Proliferating Cell Nuclear Antigen) and may inhibit NK cells’ functions. Here we studied in vitro th
Externí odkaz:
https://doaj.org/article/f163f63997ee48638e6fe3a7bfd223c8
Autor:
Muhammed Iraqi, Avishay Edri, Yariv Greenshpan, Kiran Kundu, Priyanka Bolel, Avishag Cahana, Aner Ottolenghi, Roi Gazit, Leslie Lobel, Alex Braiman, Angel Porgador
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The Ebola Virus (EBOV) glycoprotein (GP) sterically shields cell-membrane ligands to immune receptors such as human leukocyte antigen class-1 (HLA-I) and MHC class I polypeptide-related sequence A (MICA), thus mediating immunity evasion. It was sugge
Externí odkaz:
https://doaj.org/article/f3f8de4b72e44b37a2d8c0c465056e59
Autor:
Avishay Edri, Avishai Shemesh, Muhammed Iraqi, Omri Matalon, Michael Brusilovsky, Uzi Hadad, Olga Radinsky, Orly Gershoni-Yahalom, John M. Dye, Ofer Mandelboim, Mira Barda-Saad, Leslie Lobel, Angel Porgador
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The Ebola virus (EBOV) uses evasion mechanisms that directly interfere with host T-cell antiviral responses. By steric shielding of human leukocyte antigen class-1, the Ebola glycoprotein (GP) blocks interaction with T-cell receptors (TCRs), thus ren
Externí odkaz:
https://doaj.org/article/eb7ada3b6b394490ba43790efa5efe92
Autor:
Walid Shalata, Alexander Yakobson, Sarah Weissmann, Elron Oscar, Muhammed Iraqi, Waleed Kian, Nir Peled, Abed Agbarya
Publikováno v:
Oncology. 100:467-474
Introduction: Non-small cell lung cancer (NSCLC) accounts for most lung cancers and is a leading cause of cancer-related deaths in the USA. Alterations in c-MET, a tyrosine kinase receptor, have been involved in many cases of NSCLC progression and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19204d4dca66638a00bc4ee0507ea25
https://doi.org/10.1159/000525188
https://doi.org/10.1159/000525188
Autor:
Mark Schvartzman, Guillaume Le Saux, Anna Kossover, Angel Porgador, Bishnu Khand, Muhammed Iraqi, Viraj Bhingardive
Publikováno v:
Nano Letters. 21:4241-4248
T cells sense both chemical cues delivered by antigen molecules and physical cues delivered by the environmental elasticity and topography; yet, it is still largely unclear how these cues cumulatively regulate the immune activity of T cells. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f11cd4cd2a428784032c100bc5f589a
https://doi.org/10.1021/acs.nanolett.1c00245
https://doi.org/10.1021/acs.nanolett.1c00245
Autor:
Angel Porgador, David Stepensky, Roi Gazit, Susmita Ghosh, Aner Ottolenghi, Olga Radinsky, Priyanka Bolel, Kiran Kundu, Zoe V. Taylor, Muhammed Iraqi, Baisali Bhattacharya, Rhitajit Sarkar, Ron N. Apte, Elena Voronov, Yariv Greenshpan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
IL-2 is the master-regulator cytokine for T cell dependent responses and is crucial for proliferation and survival of T cells. However, IL-2-based treatments remained marginal, in part due to short half-life. Thus, we aimed to extend IL-2 half-life b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00cd5110926781cfc4ab874761a9084
https://doi.org/10.1038/s41598-021-87102-4
https://doi.org/10.1038/s41598-021-87102-4
Autor:
Hadas Landesman, Ayelet Erez, Omer Goldman, Sergey Malitsky, Sivan Galai, Alexander Brandis, Tevi Mehlman, Keyur Talsania, S. Eleonore Koehler, Yael Kuperman, Eytan Ruppin, Lisha Qiu Jin Lim, Igor Ulitsky, Angel Porgador, Yongmei Zhao, Roni Oren, Shaul Lerner, Joo Sang Lee, Maxim Itkin, Hila Weiss Tishler, Rotem Katzir, Shiran Rabinovich, Nir Peled, Noa Stettner, Lital Adler, Yuri Kuznetsov, Rom Keshet, Muhammed Iraqi, Tsai-wei Shen, Yarden Ariav
Publikováno v:
Nature Cancer
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Argininosuccinate synthase (ASS1) downregulation in different tumors has been shown to support cell proliferation and yet, in several common cancer subsets ASS1 expression associates with poor patient prognosis. Here we demonstrate that ASS1 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193f750c2610f8dd4d6709f2a1e2b1be