The novel quinoline derivative SKA-346 as a K Ca 3.1 channel selective activator.

Autor: Wong BHS; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore nkverma@ntu.edu.sg.; Interdisciplinary Graduate Programme, NTU Institute for Health Technologies (HealthTech NTU), Nanyang Technological University Singapore Singapore., Shim H; Physical and Life Sciences, Lawrence Livermore National Laboratory Livermore CA USA., Goay SSM; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore nkverma@ntu.edu.sg.; LKCMedicine-ICE Collaborative Platform, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore., Ong ST; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore nkverma@ntu.edu.sg.; LKCMedicine-ICE Collaborative Platform, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore., Muhammad Taib NAB; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore., Chai KXY; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore., Lim K; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore., Huang D; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore.; Duke-NUS Medical School Singapore., Ong CK; Lymphoma Translational Research Laboratory, Division of Cellular and Molecular Research, National Cancer Centre Singapore.; Duke-NUS Medical School Singapore., Vaiyapuri TS; MMD Lab, Institute of Molecular and Cell Biology, A*STAR Singapore., Cheah YC; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore., Wang Y; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore., Wulff H; Department of Pharmacology, University of California Davis CA USA., Webster RD; School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University Singapore Singapore., Shelat VG; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore nkverma@ntu.edu.sg.; Department of General Surgery, Tan Tock Seng Hospital Singapore., Verma NK; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore Singapore nkverma@ntu.edu.sg.

Publikováno v: RSC advances [RSC Adv] 2024 Dec 04; Vol. 14 (52), pp. 38364-38377. Date of Electronic Publication: 2024 Dec 04 (Print Publication: 2024).