Zobrazeno 1 - 3
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pro vyhledávání: '"Muhammad Nauman Jhandier"'
Autor:
Azuma Watanabe, Wajahat Z. Mehal, Ardeshir Z. Hashmi, Dawidson Assis Gomes, Fayyaz S. Sutterwala, Muhammad Nauman Jhandier, Jun Nagata, Richard A. Flavell, Muhammad A. Sohail, Yan Shi, Shamail Mahmood
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 296:G1248-G1257
The inflammasome is a cytoplasmic multiprotein complex that has recently been identified in immune cells as an important sensor of signals released by cellular injury and death. Analogous to immune cells, hepatic stellate cells (HSC) also respond to
Autor:
Wajahat Z. Mehal, Yuhshi Kuniyasu, Amir A. Qamar, Shehzad Z. Sheikh, Wyel Hakim, Muhammad Nauman Jhandier
Publikováno v:
Cellular immunology. 238(1)
Background Activated CD8 + T cells are retained by the healthy liver where the majority undergo apoptosis. The intrahepatic apoptosis of activated CD8 + T cells is enhanced by the presence of SIINFEKL peptide. It is of great interest to identify stra
Autor:
Wajahat Z. Mehal, Wyel Hakim, Ali Masud, Amir A. Qamar, Irteza Inayat, Shehzad Z. Sheikh, Muhammad Nauman Jhandier
Publikováno v:
Digestive diseases and sciences. 51(10)
Hepatic fibrogenesis is reduced in the absence of leptin. We hypothesized that leptin protects hepatic stellate cells (HSCs) from apoptosis and tested this in in vitro and in vivo systems. (i) Fas ligand (fas-L)-mediated apoptosis was induced in vitr