Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Muhammad M Hasan"'
Autor:
Muhammad M Hasan, Ethan B Mattice, José E Teixeira, Rajiv S Jumani, Erin E Stebbins, Connor E Klopfer, Sebastian E Franco, Melissa S Love, Case W McNamara, Christopher D Huston
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011906 (2024)
The apicomplexan parasite Cryptosporidium is a leading cause of childhood diarrhea in developing countries. Current treatment options are inadequate and multiple preclinical compounds are being actively pursued as potential drugs for cryptosporidiosi
Externí odkaz:
https://doaj.org/article/858bd4c9e6174385846885aacbdecc07
Autor:
Rajiv S. Jumani, Muhammad M. Hasan, Erin E. Stebbins, Liam Donnelly, Peter Miller, Connor Klopfer, Kovi Bessoff, Jose E. Teixeira, Melissa S. Love, Case W. McNamara, Christopher D. Huston
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Here, the authors provide a panel of medium-throughput assays to test potential drug candidates against different life cycle stages of Cryptosporidium with the goal to support a drug development pipeline that contains compounds with diverse molecular
Externí odkaz:
https://doaj.org/article/03437c7266734301bb9d6a058e5a30f9
Coactosin Phosphorylation Controls Entamoeba histolytica Cell Membrane Protrusions and Cell Motility
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Invasion of the colon wall by Entamoeba histolytica during amoebic dysentery entails migration of trophozoites through tissue layers that are rich in extracellular matrix. Transcriptional silencing of the E. histolytica surface metalloprotea
Externí odkaz:
https://doaj.org/article/cde7775a75114ada93f1cfd3282f8755
The intraerythrocytic malaria parasitePlasmodium falciparumexports hundreds of proteins into the host red blood cell (RBC). Most are targeted to the ER by a stretch of hydrophobic amino acids and cleaved further downstream at a conserved motif called
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50d5830eb275fc83afe75b81df51c5fa
https://doi.org/10.1101/2023.05.17.541120
https://doi.org/10.1101/2023.05.17.541120
Autor:
Alexander J. Polino, Muhammad M. Hasan, Katherine Floyd, Yolotzin Avila-Cruz, Yujuan Yang, Daniel E. Goldberg
Publikováno v:
Journal of Cell Science. 136
N-terminal acetylation is a common eukaryotic protein modification that involves the addition of an acetyl group to the N-terminus of a polypeptide. This modification is largely performed by cytosolic N-terminal acetyltransferases (NATs). Most associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::653d4cfa739ec5739791c852f1225a14
https://doi.org/10.1242/jcs.260551
https://doi.org/10.1242/jcs.260551
Publikováno v:
Minerva Psychiatry. 63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e096b0bcb1437f027e9276d6ffe222eb
https://doi.org/10.23736/s2724-6612.21.02167-9
https://doi.org/10.23736/s2724-6612.21.02167-9
Autor:
Erkang Fan, Jose E. Teixeira, Adam Sateriale, Christopher D. Huston, John R. Gillespie, Peter Jonathon Miller, Muhammad M. Hasan, Erin E. Stebbins, Frederick S. Buckner, Zhongsheng Zhang, Robert K. M. Choy, Christophe L. M. J. Verlinde, Ranae M. Ranade, Eugenio L. de Hostos, Aisha Mushtaq, Damon M. Osbourn, David W. Griggs
Publikováno v:
Antimicrob Agents Chemother
The intestinal protozoan Cryptosporidium is a leading cause of diarrheal disease and mortality in young children. There is currently no fully effective treatment for cryptosporidiosis, which has stimulated interest in anticryptosporidial development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9d4e0b2a43263d5bede9707a02798d
https://doi.org/10.1128/aac.00023-21
https://doi.org/10.1128/aac.00023-21
Autor:
Sumiti Vinayak, Amy K. Wernimont, Chris Walpole, Sean Eckley, Jose E. Teixeira, Rajiv S. Jumani, Amit Sharma, Manmohan Sharma, Xianshui Yu, Christina Scherer, Nobutaka Kato, Muhammad M. Hasan, Bruno Melillo, Arthur Gonse, Christopher D. Huston, Stuart L. Schreiber, Eamon Comer, Boris Striepen, Case W. McNamara, Erin E. Stebbins, Briana I. McLeod, Julien Borrel, Jayesh Tandel, Melissa S. Love, Peter J. Miller, Mingliang Zhang
Publikováno v:
Science Translational Medicine. 12
Cryptosporidium is a protozoan parasite and a leading cause of diarrheal disease and mortality in young children. Currently, there are no fully effective treatments available to cure infection with this diarrheal pathogen. In this study, we report a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d13029b67e787a6f32622aa1a3983584
https://doi.org/10.1126/scitranslmed.aba8412
https://doi.org/10.1126/scitranslmed.aba8412
Coactosin Phosphorylation Controls Entamoeba histolytica Cell Membrane Protrusions and Cell Motility
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
mBio
mBio
Invasive amoebiasis, caused by the intestinal parasite Entamoeba histolytica, causes life-threatening diarrhea and liver abscesses, but, for unknown reasons, only approximately 10% of E. histolytica infections become symptomatic. A key requirement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db13bc2b7b5f6a61efc6db6b49c370fe
https://journals.asm.org/doi/10.1128/mBio.00660-20
https://journals.asm.org/doi/10.1128/mBio.00660-20
Supply chain risk management is a crucial part of any strategy across all sorts of industries. The apparel industry in Bangladesh have a great contribution on its total GDP (gross domestic product). Due to the sophisticated nature of the industry, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bcb0b2e860bded18b3bbdec0f328f0